FR2259588A1 - O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects - Google Patents

O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects

Info

Publication number
FR2259588A1
FR2259588A1 FR7403288A FR7403288A FR2259588A1 FR 2259588 A1 FR2259588 A1 FR 2259588A1 FR 7403288 A FR7403288 A FR 7403288A FR 7403288 A FR7403288 A FR 7403288A FR 2259588 A1 FR2259588 A1 FR 2259588A1
Authority
FR
France
Prior art keywords
acid
antiinflammatory
esters
salts
analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7403288A
Other languages
French (fr)
Other versions
FR2259588B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GRIGNARD ROBERT FR
Original Assignee
GRIGNARD ROBERT FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GRIGNARD ROBERT FR filed Critical GRIGNARD ROBERT FR
Priority to FR7403288A priority Critical patent/FR2259588A1/en
Publication of FR2259588A1 publication Critical patent/FR2259588A1/en
Application granted granted Critical
Publication of FR2259588B1 publication Critical patent/FR2259588B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom

Abstract

O-Malylsalicylic acid, its salts and esters are of formula (I) (where R' and R2 are H, alkali or alkaline eath metal cations, Al, opt. substd. aliphatic or aromatic amines, quat. ammonium ions, residues of amino acids or opt. substd. aminoalcohols, or R2 may be the group The cpds. have antipyretic and analgesic action of salicylic acid and are free of toxic actions, e.g. induction of tinnitus. The antiinflammatory and decongestant action of alicylic acid is improved by the presence in the molecule of a constituent of the Krebs cycle.
FR7403288A 1974-01-31 1974-01-31 O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects Granted FR2259588A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7403288A FR2259588A1 (en) 1974-01-31 1974-01-31 O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7403288A FR2259588A1 (en) 1974-01-31 1974-01-31 O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects

Publications (2)

Publication Number Publication Date
FR2259588A1 true FR2259588A1 (en) 1975-08-29
FR2259588B1 FR2259588B1 (en) 1977-09-09

Family

ID=9134303

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7403288A Granted FR2259588A1 (en) 1974-01-31 1974-01-31 O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects

Country Status (1)

Country Link
FR (1) FR2259588A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374039A1 (en) * 1976-12-15 1978-07-13 Procter & Gamble COMPOSITIONS CONTAINING A DERIVATIVE OF SALICYLIC ACID AND MEDICINAL APPLICATIONS
WO2015043688A1 (en) * 2013-09-27 2015-04-02 Ratiopharm Gmbh Prodrugs of monomethyl fumarate (mmf)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374039A1 (en) * 1976-12-15 1978-07-13 Procter & Gamble COMPOSITIONS CONTAINING A DERIVATIVE OF SALICYLIC ACID AND MEDICINAL APPLICATIONS
WO2015043688A1 (en) * 2013-09-27 2015-04-02 Ratiopharm Gmbh Prodrugs of monomethyl fumarate (mmf)

Also Published As

Publication number Publication date
FR2259588B1 (en) 1977-09-09

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