FR2244499A1 - Indol-3-ylformaldoxime carbamates - for treating anxiety epilepsy, cardiac arrhythmias, asthma, intestinal spasm, peptic ulcer, cardiac insufficiency - Google Patents

Indol-3-ylformaldoxime carbamates - for treating anxiety epilepsy, cardiac arrhythmias, asthma, intestinal spasm, peptic ulcer, cardiac insufficiency

Info

Publication number
FR2244499A1
FR2244499A1 FR7320690A FR7320690A FR2244499A1 FR 2244499 A1 FR2244499 A1 FR 2244499A1 FR 7320690 A FR7320690 A FR 7320690A FR 7320690 A FR7320690 A FR 7320690A FR 2244499 A1 FR2244499 A1 FR 2244499A1
Authority
FR
France
Prior art keywords
cardiac
carbamates
indol
ylformaldoxime
epilepsy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7320690A
Other languages
French (fr)
Other versions
FR2244499B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7320690A priority Critical patent/FR2244499A1/en
Publication of FR2244499A1 publication Critical patent/FR2244499A1/en
Application granted granted Critical
Publication of FR2244499B1 publication Critical patent/FR2244499B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Abstract

Indol-3-yl-formaldoxime carbamates of formula: (where R is opt. unsaturated 1-4C alkyl, phenyl opt. substd. by one or more halogen or 1-4C alkoxy) have antiarrhythmic, cardiac analeptic, antiinflammatory, sedative, analgesic, anticonvulsant, anxiolytic, diuretic bronchodilator and anticholinergic activity.
FR7320690A 1973-06-07 1973-06-07 Indol-3-ylformaldoxime carbamates - for treating anxiety epilepsy, cardiac arrhythmias, asthma, intestinal spasm, peptic ulcer, cardiac insufficiency Granted FR2244499A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7320690A FR2244499A1 (en) 1973-06-07 1973-06-07 Indol-3-ylformaldoxime carbamates - for treating anxiety epilepsy, cardiac arrhythmias, asthma, intestinal spasm, peptic ulcer, cardiac insufficiency

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7320690A FR2244499A1 (en) 1973-06-07 1973-06-07 Indol-3-ylformaldoxime carbamates - for treating anxiety epilepsy, cardiac arrhythmias, asthma, intestinal spasm, peptic ulcer, cardiac insufficiency

Publications (2)

Publication Number Publication Date
FR2244499A1 true FR2244499A1 (en) 1975-04-18
FR2244499B1 FR2244499B1 (en) 1976-12-31

Family

ID=9120632

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7320690A Granted FR2244499A1 (en) 1973-06-07 1973-06-07 Indol-3-ylformaldoxime carbamates - for treating anxiety epilepsy, cardiac arrhythmias, asthma, intestinal spasm, peptic ulcer, cardiac insufficiency

Country Status (1)

Country Link
FR (1) FR2244499A1 (en)

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0470805A1 (en) * 1990-08-08 1992-02-12 American Home Products Corporation Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents
WO2000066096A2 (en) * 1999-04-30 2000-11-09 Merab Lomia Use of antiepileptics for treating respiratory disorders, in particular asthmatic disorders
WO2005030192A1 (en) * 2003-09-25 2005-04-07 Wyeth 4- (1h-indol-3-yl-methylideneaminoxy-propoxy) -benzioc acid derivatives and related compounds as pai-1 inhibitors for the treatment of impairment of the fibrinolytic system and of thrombisis
US7074817B2 (en) 2001-06-20 2006-07-11 Wyeth Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7078429B2 (en) 2002-12-10 2006-07-18 Wyeth Substituted 3-carbonyl-1H-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7101903B2 (en) 2002-12-10 2006-09-05 Wyeth Substituted dihydropyrano indole-3,4-dione derivatives as inhibitiors of plasminogen activator inhibitor-1 (PAI-1)
US7141592B2 (en) 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7163954B2 (en) 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7259182B2 (en) 2002-12-10 2007-08-21 Wyeth Aryl, aryloxy, and aklyloxy substituted 1H-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7348351B2 (en) 2002-12-10 2008-03-25 Wyeth Substituted 3-alkyl and 3-arylalkyl 1H-indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7351730B2 (en) 2001-06-20 2008-04-01 Wyeth Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7411083B2 (en) 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7420083B2 (en) 2003-09-25 2008-09-02 Wyeth Substituted aryloximes
US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7605172B2 (en) 2004-08-23 2009-10-20 Wyeth Thiazolo-naphthyl acids
US7683091B2 (en) 2005-08-17 2010-03-23 Wyeth Substituted indoles and methods of their use
US7754747B2 (en) 2004-08-23 2010-07-13 Wyeth Llc Oxazolo-naphthyl acids
WO2015152153A1 (en) * 2014-04-04 2015-10-08 株式会社Adeka Oxime ester compound and photopolymerization initiator containing said compound
WO2017051680A1 (en) * 2015-09-25 2017-03-30 株式会社Adeka Oxime ester compound and polymerization initiator containing said compound
WO2019117162A1 (en) * 2017-12-13 2019-06-20 株式会社Adeka Compound, latent base generator, photosensitive resin composition containing said compound, and cured product

Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0470805A1 (en) * 1990-08-08 1992-02-12 American Home Products Corporation Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents
WO2000066096A2 (en) * 1999-04-30 2000-11-09 Merab Lomia Use of antiepileptics for treating respiratory disorders, in particular asthmatic disorders
WO2000066096A3 (en) * 1999-04-30 2001-03-22 Merab Lomia Use of antiepileptics for treating respiratory disorders, in particular asthmatic disorders
US7629377B2 (en) 2001-06-20 2009-12-08 Wyeth Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
US7351730B2 (en) 2001-06-20 2008-04-01 Wyeth Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
US7074817B2 (en) 2001-06-20 2006-07-11 Wyeth Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7368471B2 (en) 2001-06-20 2008-05-06 Wyeth Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7101903B2 (en) 2002-12-10 2006-09-05 Wyeth Substituted dihydropyrano indole-3,4-dione derivatives as inhibitiors of plasminogen activator inhibitor-1 (PAI-1)
US7566791B2 (en) 2002-12-10 2009-07-28 Wyeth Substituted 3-carbonyl-1h-indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7259182B2 (en) 2002-12-10 2007-08-21 Wyeth Aryl, aryloxy, and aklyloxy substituted 1H-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7459478B2 (en) 2002-12-10 2008-12-02 Wyeth Substituted dihydropyrano indole-3,4-dione derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7348351B2 (en) 2002-12-10 2008-03-25 Wyeth Substituted 3-alkyl and 3-arylalkyl 1H-indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7078429B2 (en) 2002-12-10 2006-07-18 Wyeth Substituted 3-carbonyl-1H-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7674818B2 (en) 2002-12-10 2010-03-09 Wyeth Llc Aryl, aryloxy, alkyloxy substituted 1H-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7411083B2 (en) 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7420083B2 (en) 2003-09-25 2008-09-02 Wyeth Substituted aryloximes
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7803835B2 (en) 2003-09-25 2010-09-28 Wyeth Llc Substituted acetic acid derivatives
US7163954B2 (en) 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7342039B2 (en) 2003-09-25 2008-03-11 Wyeth Substituted indole oximes
US7141592B2 (en) 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
WO2005030192A1 (en) * 2003-09-25 2005-04-07 Wyeth 4- (1h-indol-3-yl-methylideneaminoxy-propoxy) -benzioc acid derivatives and related compounds as pai-1 inhibitors for the treatment of impairment of the fibrinolytic system and of thrombisis
US7605172B2 (en) 2004-08-23 2009-10-20 Wyeth Thiazolo-naphthyl acids
US7754747B2 (en) 2004-08-23 2010-07-13 Wyeth Llc Oxazolo-naphthyl acids
US7683091B2 (en) 2005-08-17 2010-03-23 Wyeth Substituted indoles and methods of their use
WO2015152153A1 (en) * 2014-04-04 2015-10-08 株式会社Adeka Oxime ester compound and photopolymerization initiator containing said compound
CN106132929A (en) * 2014-04-04 2016-11-16 株式会社艾迪科 Oxime ester compound and the Photoepolymerizationinitiater initiater containing this compound
JPWO2015152153A1 (en) * 2014-04-04 2017-04-13 株式会社Adeka Oxime ester compound and photopolymerization initiator containing the compound
US10189847B2 (en) 2014-04-04 2019-01-29 Adeka Corporation Oxime ester compound and photopolymerization initiator containing said compound
WO2017051680A1 (en) * 2015-09-25 2017-03-30 株式会社Adeka Oxime ester compound and polymerization initiator containing said compound
CN107635960A (en) * 2015-09-25 2018-01-26 株式会社艾迪科 Oxime ester compound and the polymerization initiator containing the compound
JPWO2017051680A1 (en) * 2015-09-25 2018-07-12 株式会社Adeka Oxime ester compound and polymerization initiator containing the compound
CN107635960B (en) * 2015-09-25 2022-02-01 株式会社艾迪科 Oxime ester compound and polymerization initiator containing the same
WO2019117162A1 (en) * 2017-12-13 2019-06-20 株式会社Adeka Compound, latent base generator, photosensitive resin composition containing said compound, and cured product
CN111417623A (en) * 2017-12-13 2020-07-14 株式会社艾迪科 Compound, latent base generator, photosensitive resin composition containing the compound, and cured product
JPWO2019117162A1 (en) * 2017-12-13 2021-01-07 株式会社Adeka Compounds, latent base generators, photosensitive resin compositions containing the compounds, and cured products.

Also Published As

Publication number Publication date
FR2244499B1 (en) 1976-12-31

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