FR2242111A1 - Insolubilised snake venom enzymes - for removing fibrinogen from blood or plasma - Google Patents

Insolubilised snake venom enzymes - for removing fibrinogen from blood or plasma

Info

Publication number
FR2242111A1
FR2242111A1 FR7429122A FR7429122A FR2242111A1 FR 2242111 A1 FR2242111 A1 FR 2242111A1 FR 7429122 A FR7429122 A FR 7429122A FR 7429122 A FR7429122 A FR 7429122A FR 2242111 A1 FR2242111 A1 FR 2242111A1
Authority
FR
France
Prior art keywords
fibrinogen
blood
enzyme
snake venom
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7429122A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Nutritional Products AG
Original Assignee
Pentapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm AG filed Critical Pentapharm AG
Publication of FR2242111A1 publication Critical patent/FR2242111A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier

Abstract

Insolubilized enzymes for removing fibrinogen from human or animal blood, plasma or fractions thereof before analysing for or recovering, blood coagulation factors, comprise an insoluble carrier to which is bound a thrombinlike enzyme derived from snake venom, the enzyme being capable of converting fibrinogen to fibrin. The carrier is suitably reactivated cellulose, polydextran, agarose, polypeptides, polystyrene, polyacrylic acids, polyacrylamide or copolymers. Removal of fibrinogen is essential before coagulation factors VIII or IX, prothrombin or plasminogen etc. can be assayed or revocered. The use of unbound snake venom enzymes is known; the present compsn. prevents contamination of the fibrinogen-free blood with excess enzyme. The enzyme may be easily sepd. from ppd. fibrin and reused.
FR7429122A 1973-08-27 1974-08-26 Insolubilised snake venom enzymes - for removing fibrinogen from blood or plasma Withdrawn FR2242111A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1235373 1973-08-27

Publications (1)

Publication Number Publication Date
FR2242111A1 true FR2242111A1 (en) 1975-03-28

Family

ID=4382232

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7429122A Withdrawn FR2242111A1 (en) 1973-08-27 1974-08-26 Insolubilised snake venom enzymes - for removing fibrinogen from blood or plasma

Country Status (2)

Country Link
DE (1) DE2440254A1 (en)
FR (1) FR2242111A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008100A1 (en) * 1978-08-07 1980-02-20 BASF Aktiengesellschaft Process for the production of macroporous polymeric support material for the covalent binding of proteins

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661920B1 (en) * 1990-05-10 1995-10-06 Serbio METHOD FOR DETERMINING A PLASMINOGEN ACTIVATOR AND ITS INHIBITOR.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008100A1 (en) * 1978-08-07 1980-02-20 BASF Aktiengesellschaft Process for the production of macroporous polymeric support material for the covalent binding of proteins

Also Published As

Publication number Publication date
DE2440254A1 (en) 1975-03-06

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Legal Events

Date Code Title Description
RE Withdrawal of published application