FR2230377A1 - Substd triiodobenzoic acid esters - x-ray contrast agents - Google Patents

Substd triiodobenzoic acid esters - x-ray contrast agents

Info

Publication number
FR2230377A1
FR2230377A1 FR7318302A FR7318302A FR2230377A1 FR 2230377 A1 FR2230377 A1 FR 2230377A1 FR 7318302 A FR7318302 A FR 7318302A FR 7318302 A FR7318302 A FR 7318302A FR 2230377 A1 FR2230377 A1 FR 2230377A1
Authority
FR
France
Prior art keywords
contrast agents
ray contrast
substd
acid esters
triiodobenzoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7318302A
Other languages
French (fr)
Other versions
FR2230377B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to FR7318302A priority Critical patent/FR2230377A1/en
Publication of FR2230377A1 publication Critical patent/FR2230377A1/en
Application granted granted Critical
Publication of FR2230377B1 publication Critical patent/FR2230377B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Acetoxy and pivaloyloxymethyl 5-acetamido-2,4,6-triiodo-N-methyl iso-phthalamates are useful as X-ray contrast agents. They are prepd. by esterification. In an example, sodium 5-acetamido-2,4,6-triiodo-N-methyl-isophthalamate reacts with chloromethyl acetate in DMF at room temp. to give the acetoxymethyl ester.
FR7318302A 1973-05-21 1973-05-21 Substd triiodobenzoic acid esters - x-ray contrast agents Granted FR2230377A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7318302A FR2230377A1 (en) 1973-05-21 1973-05-21 Substd triiodobenzoic acid esters - x-ray contrast agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7318302A FR2230377A1 (en) 1973-05-21 1973-05-21 Substd triiodobenzoic acid esters - x-ray contrast agents

Publications (2)

Publication Number Publication Date
FR2230377A1 true FR2230377A1 (en) 1974-12-20
FR2230377B1 FR2230377B1 (en) 1976-08-13

Family

ID=9119635

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7318302A Granted FR2230377A1 (en) 1973-05-21 1973-05-21 Substd triiodobenzoic acid esters - x-ray contrast agents

Country Status (1)

Country Link
FR (1) FR2230377A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354549A (en) * 1987-07-24 1994-10-11 Nycomed Imaging As Iodinated esters

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1172953A (en) * 1956-03-13 1959-02-18 Bayer Ag Process for the preparation of halogenated amino-isophthalic acids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1172953A (en) * 1956-03-13 1959-02-18 Bayer Ag Process for the preparation of halogenated amino-isophthalic acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354549A (en) * 1987-07-24 1994-10-11 Nycomed Imaging As Iodinated esters

Also Published As

Publication number Publication date
FR2230377B1 (en) 1976-08-13

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Legal Events

Date Code Title Description
ST Notification of lapse