FR2226993A1 - Keto acid compsns. - for increasing protein synthesis and suppressing urea formation - Google Patents

Keto acid compsns. - for increasing protein synthesis and suppressing urea formation

Info

Publication number
FR2226993A1
FR2226993A1 FR7325650A FR7325650A FR2226993A1 FR 2226993 A1 FR2226993 A1 FR 2226993A1 FR 7325650 A FR7325650 A FR 7325650A FR 7325650 A FR7325650 A FR 7325650A FR 2226993 A1 FR2226993 A1 FR 2226993A1
Authority
FR
France
Prior art keywords
compsns
keto acid
protein synthesis
increasing protein
urea formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7325650A
Other languages
French (fr)
Other versions
FR2226993B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MACKENSIE WALKER
Original Assignee
MACKENSIE WALKER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MACKENSIE WALKER filed Critical MACKENSIE WALKER
Publication of FR2226993A1 publication Critical patent/FR2226993A1/en
Application granted granted Critical
Publication of FR2226993B1 publication Critical patent/FR2226993B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpsns. of keto acids derived from essential amino acids are administered orally or parenterally. Keto acid analogs include those of valine, phenyl alanine, luethionine (iso)leucene, histidine, tryptophane, lysine, threonine and argenine.
FR7325650A 1972-07-13 1973-07-12 Keto acid compsns. - for increasing protein synthesis and suppressing urea formation Granted FR2226993A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27098672A 1972-07-12 1972-07-12
US35532773A 1973-04-30 1973-04-30

Publications (2)

Publication Number Publication Date
FR2226993A1 true FR2226993A1 (en) 1974-11-22
FR2226993B1 FR2226993B1 (en) 1977-07-08

Family

ID=26954620

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7325650A Granted FR2226993A1 (en) 1972-07-13 1973-07-12 Keto acid compsns. - for increasing protein synthesis and suppressing urea formation

Country Status (5)

Country Link
JP (1) JPS4950121A (en)
CA (1) CA1027478A (en)
DE (1) DE2335215B2 (en)
FR (1) FR2226993A1 (en)
IL (1) IL42726A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2828620A1 (en) * 1977-07-01 1979-02-01 Pfizer MEDICINAL PRODUCTS CONTAINING PHENYLGLYOXYL ACID DERIVATIVES AND THE USE THEREOF
FR2454434A1 (en) * 1979-04-18 1980-11-14 Univ Johns Hopkins MIXED SALTS OF ESSENTIAL OR SEMI-ESSENTIAL AMINO ACIDS AND THE LIKE, NITROGEN FREE, OF SUCH ACIDS, AND THEIR USE IN THE TREATMENT OF RENAL AND HEPATIC DISORDERS
EP0227545A2 (en) * 1985-12-23 1987-07-01 The Johns Hopkins University Nutritional supplement for treatment of uremia

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2530246A1 (en) * 1975-07-07 1977-01-13 Fresenius Chem Pharm Ind L-AMINO ACID MIXTURES FOR PARENTERAL OR ORAL USE
DE2531299A1 (en) * 1975-07-12 1977-01-13 Fresenius Chem Pharm Ind MIXTURES CONTAINING L-AMINO AND HYDROXY AND / OR KETO ACIDS FOR PARENTERAL OR ORAL USE
DE2636828A1 (en) * 1976-08-16 1978-02-23 Fresenius Chem Pharm Ind (L)-Aminoacid mixt. for treating liver insufficiency - contains isoleucine, leucine, lysine, methionine and cysteine or cystine and non-essential aminoacid(s)
US4320146A (en) 1978-03-17 1982-03-16 The Johns Hopkins University Treatment of hepatic and renal disorders with ornithine and arginine salts of branched chain keto acids
US4228099A (en) * 1978-03-17 1980-10-14 The Johns Hopkins University Ornithine and arginine salts of branched chain keto acids and uses in treatment of hepatic and renal disorders
SE8803143L (en) * 1988-09-07 1990-03-08 Kabivitrum Ab ALTERNATIVE ENERGY SUBSTRATE
DE3936319C3 (en) * 1989-11-01 1997-05-07 Bartz Volker Phosphate binder for oral administration
DE3940052A1 (en) * 1989-12-04 1991-06-06 Nephro Medica Pharma DIALYSIS AND SPOOL SOLUTION FOR INTRAPERITONEAL ADMINISTRATION
DE3943424A1 (en) * 1989-12-30 1991-07-04 Nephro Medica Pharma Solns. for intravenous nutrition - contg. alpha-keto acids, for patients with kidney conditions, avoids nitrogen cpd. build-up
EP2699110A1 (en) * 2011-04-18 2014-02-26 Nestec S.A. Nutritional compositions having alpha-hica and alpha-ketoglutarate

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2828620A1 (en) * 1977-07-01 1979-02-01 Pfizer MEDICINAL PRODUCTS CONTAINING PHENYLGLYOXYL ACID DERIVATIVES AND THE USE THEREOF
FR2454434A1 (en) * 1979-04-18 1980-11-14 Univ Johns Hopkins MIXED SALTS OF ESSENTIAL OR SEMI-ESSENTIAL AMINO ACIDS AND THE LIKE, NITROGEN FREE, OF SUCH ACIDS, AND THEIR USE IN THE TREATMENT OF RENAL AND HEPATIC DISORDERS
EP0227545A2 (en) * 1985-12-23 1987-07-01 The Johns Hopkins University Nutritional supplement for treatment of uremia
EP0227545A3 (en) * 1985-12-23 1988-01-20 The John Hopkins University Nutritional supplement for treatment of uremia

Also Published As

Publication number Publication date
CA1027478A (en) 1978-03-07
FR2226993B1 (en) 1977-07-08
IL42726A (en) 1977-10-31
AU5794173A (en) 1975-01-16
DE2335215B2 (en) 1979-04-05
JPS4950121A (en) 1974-05-15
DE2335215A1 (en) 1974-01-31

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse