FR2222374A1 - N-substd indole derivs prepn - esp pharmaceutically active alkaloids - Google Patents

N-substd indole derivs prepn - esp pharmaceutically active alkaloids

Info

Publication number
FR2222374A1
FR2222374A1 FR7407934A FR7407934A FR2222374A1 FR 2222374 A1 FR2222374 A1 FR 2222374A1 FR 7407934 A FR7407934 A FR 7407934A FR 7407934 A FR7407934 A FR 7407934A FR 2222374 A1 FR2222374 A1 FR 2222374A1
Authority
FR
France
Prior art keywords
substd
esp
pharmaceutically active
indole
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7407934A
Other languages
French (fr)
Other versions
FR2222374B3 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omnium Chimique SA
Original Assignee
Omnium Chimique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnium Chimique SA filed Critical Omnium Chimique SA
Publication of FR2222374A1 publication Critical patent/FR2222374A1/en
Application granted granted Critical
Publication of FR2222374B3 publication Critical patent/FR2222374B3/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D459/00—Heterocyclic compounds containing benz [g] indolo [2, 3-a] quinolizine ring systems, e.g. yohimbine; 16, 18-lactones thereof, e.g. reserpic acid lactone

Abstract

N-Substd. indole derivs are prepd. by prepg. 2,3-dihydro-indoles from the starting indoles, substituting these on the N-atom, and dehydrogenating the 2,3-dihdyro-N-substd. indoles. The N-methyl derivs of reserpiline, tetraphylline and raubasine are claimed as new as are some 2,3-dihydro- and N-methyl-dihydro-alkaloid inters. The reactions are carried out by conventional methods. The therapeutic props. of indole derivs are considerably modified by N-substn.
FR7407934A 1973-03-09 1974-03-08 N-substd indole derivs prepn - esp pharmaceutically active alkaloids Granted FR2222374A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE796521 1973-03-09

Publications (2)

Publication Number Publication Date
FR2222374A1 true FR2222374A1 (en) 1974-10-18
FR2222374B3 FR2222374B3 (en) 1976-12-17

Family

ID=3860825

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7407934A Granted FR2222374A1 (en) 1973-03-09 1974-03-08 N-substd indole derivs prepn - esp pharmaceutically active alkaloids

Country Status (1)

Country Link
FR (1) FR2222374A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032889A1 (en) * 1980-01-09 1981-07-29 OMNICHEM Société anonyme 1,10-Dimethyl-oxayohimbane derivatives and medicaments containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032889A1 (en) * 1980-01-09 1981-07-29 OMNICHEM Société anonyme 1,10-Dimethyl-oxayohimbane derivatives and medicaments containing them
EP0032889B1 (en) * 1980-01-09 1984-02-15 OMNICHEM Société anonyme 1,10-dimethyl-oxayohimbane derivatives and medicaments containing them

Also Published As

Publication number Publication date
FR2222374B3 (en) 1976-12-17

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