FR2216250A1 - Salidiuretic furosemide prepn - from furfural and a cyano aniline followed by reduction and hydrolysis - Google Patents

Salidiuretic furosemide prepn - from furfural and a cyano aniline followed by reduction and hydrolysis

Info

Publication number
FR2216250A1
FR2216250A1 FR7303976A FR7303976A FR2216250A1 FR 2216250 A1 FR2216250 A1 FR 2216250A1 FR 7303976 A FR7303976 A FR 7303976A FR 7303976 A FR7303976 A FR 7303976A FR 2216250 A1 FR2216250 A1 FR 2216250A1
Authority
FR
France
Prior art keywords
furosemide
furfural
reduction
hydrolysis
salidiuretic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7303976A
Other languages
French (fr)
Other versions
FR2216250B3 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7303976A priority Critical patent/FR2216250A1/en
Publication of FR2216250A1 publication Critical patent/FR2216250A1/en
Application granted granted Critical
Publication of FR2216250B3 publication Critical patent/FR2216250B3/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Furosemide (I): is prepared by treating 2-cyano-4-sulphamoyl-5-chloro aniline with furfural to give the Schiff's base, reduction with a reducing agent or catalytically, followed by acid or alkaline hydrolysis of the cyano gp.
FR7303976A 1973-02-05 1973-02-05 Salidiuretic furosemide prepn - from furfural and a cyano aniline followed by reduction and hydrolysis Granted FR2216250A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7303976A FR2216250A1 (en) 1973-02-05 1973-02-05 Salidiuretic furosemide prepn - from furfural and a cyano aniline followed by reduction and hydrolysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7303976A FR2216250A1 (en) 1973-02-05 1973-02-05 Salidiuretic furosemide prepn - from furfural and a cyano aniline followed by reduction and hydrolysis

Publications (2)

Publication Number Publication Date
FR2216250A1 true FR2216250A1 (en) 1974-08-30
FR2216250B3 FR2216250B3 (en) 1976-01-30

Family

ID=9114341

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7303976A Granted FR2216250A1 (en) 1973-02-05 1973-02-05 Salidiuretic furosemide prepn - from furfural and a cyano aniline followed by reduction and hydrolysis

Country Status (1)

Country Link
FR (1) FR2216250A1 (en)

Also Published As

Publication number Publication date
FR2216250B3 (en) 1976-01-30

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Legal Events

Date Code Title Description
ST Notification of lapse