FR2209553A1 - Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents - Google Patents

Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents

Info

Publication number
FR2209553A1
FR2209553A1 FR7243780A FR7243780A FR2209553A1 FR 2209553 A1 FR2209553 A1 FR 2209553A1 FR 7243780 A FR7243780 A FR 7243780A FR 7243780 A FR7243780 A FR 7243780A FR 2209553 A1 FR2209553 A1 FR 2209553A1
Authority
FR
France
Prior art keywords
lipotropic
choleretic
antitoxic
cholines
steatosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7243780A
Other languages
French (fr)
Other versions
FR2209553B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Priority to FR7243780A priority Critical patent/FR2209553A1/en
Priority to DE19732359245 priority patent/DE2359245A1/en
Priority to BE138415A priority patent/BE808092A/en
Priority to AR25134473A priority patent/AR198713A1/en
Priority to JP13803873A priority patent/JPS4994650A/ja
Priority to NL7316813A priority patent/NL7316813A/xx
Publication of FR2209553A1 publication Critical patent/FR2209553A1/en
Application granted granted Critical
Publication of FR2209553B1 publication Critical patent/FR2209553B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/18—Esters of thiophosphoric acids with hydroxyaryl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Title cpds of formula (I) (where n = 2 or 3, A is morpholino, 1-(p-methylphenyl) ethoxy 1-phenylpropoxy or 2-acetamido carbonyl phenoxy) are prepd. by reacting cpd. of formula (II) with ME3N. In an example (I, n = 2 A = morpholino) is prepd. by reacting morpholine with ethylene phosphate chloride and the prod. with Me3N.
FR7243780A 1972-12-08 1972-12-08 Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents Granted FR2209553A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR7243780A FR2209553A1 (en) 1972-12-08 1972-12-08 Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents
DE19732359245 DE2359245A1 (en) 1972-12-08 1973-11-28 PHOSPHORYLATED DERIVATIVES OF CHOLINE AND HOMOCHOLINE, PROCESS FOR THE PREPARATION OF SUCH DERIVATIVES, AND APPLICATION OF SUCH DERIVATIVES IN THERAPY
BE138415A BE808092A (en) 1972-12-08 1973-11-30 PHOSPHORY DERIVATIVES OF CHOLINE AND HOMOCHOLIN THEIR PREPARATION AND THEIR APPLICATIONS IN THERAPEUTICS
AR25134473A AR198713A1 (en) 1972-12-08 1973-12-04 PROCEDURE FOR OBTAINING PHOSPHORYLATED DERIVATIVES OF THE HILL AND HOMOCOLIN
JP13803873A JPS4994650A (en) 1972-12-08 1973-12-07
NL7316813A NL7316813A (en) 1972-12-08 1973-12-07

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7243780A FR2209553A1 (en) 1972-12-08 1972-12-08 Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents

Publications (2)

Publication Number Publication Date
FR2209553A1 true FR2209553A1 (en) 1974-07-05
FR2209553B1 FR2209553B1 (en) 1975-11-28

Family

ID=9108420

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7243780A Granted FR2209553A1 (en) 1972-12-08 1972-12-08 Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents

Country Status (6)

Country Link
JP (1) JPS4994650A (en)
AR (1) AR198713A1 (en)
BE (1) BE808092A (en)
DE (1) DE2359245A1 (en)
FR (1) FR2209553A1 (en)
NL (1) NL7316813A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003075902A2 (en) * 2002-03-13 2003-09-18 Yeda Research And Development Co. Ltd. Derivatives of 1, 3-cyclic propanediol phosphate and their action as cell stimulants

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097752B2 (en) * 2002-10-30 2012-01-17 Makscientific, Llc Antiprotozoal ring-substituted phospholipids

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003075902A2 (en) * 2002-03-13 2003-09-18 Yeda Research And Development Co. Ltd. Derivatives of 1, 3-cyclic propanediol phosphate and their action as cell stimulants
WO2003075902A3 (en) * 2002-03-13 2005-04-14 Yeda Res & Dev Derivatives of 1, 3-cyclic propanediol phosphate and their action as cell stimulants

Also Published As

Publication number Publication date
BE808092A (en) 1974-05-30
FR2209553B1 (en) 1975-11-28
NL7316813A (en) 1974-06-11
JPS4994650A (en) 1974-09-09
AR198713A1 (en) 1974-07-15
DE2359245A1 (en) 1974-06-12

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Legal Events

Date Code Title Description
ST Notification of lapse