FR2196173A1 - Transforming anergic cancer patients into allergic state - with 2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole - Google Patents

Transforming anergic cancer patients into allergic state - with 2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole

Info

Publication number
FR2196173A1
FR2196173A1 FR7330085A FR7330085A FR2196173A1 FR 2196173 A1 FR2196173 A1 FR 2196173A1 FR 7330085 A FR7330085 A FR 7330085A FR 7330085 A FR7330085 A FR 7330085A FR 2196173 A1 FR2196173 A1 FR 2196173A1
Authority
FR
France
Prior art keywords
anergic
phenylimidazo
thiazole
tetrahydro
cancer patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7330085A
Other languages
French (fr)
Other versions
FR2196173B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of FR2196173A1 publication Critical patent/FR2196173A1/en
Application granted granted Critical
Publication of FR2196173B1 publication Critical patent/FR2196173B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles

Abstract

In an investigation of the transformation of anergic patients (with no delayed hypersensitive reaction to skin-sensitizing antigens) into an allergic state (in which the above reaction is present, an effective amt. of 2,3,5,6-tetrahydro-6-phenylimidazo [2,1-b] thiazole (I), or its acid-addn. salts is administered to the patient and, after another challenge with the antigen (pref. 2,4-dinitrochlorobenzene or tuberculin), the patient is again examined for the required transformation. There is a connection between the ability of cancer patients to react to certain antigens and their operability, and (I) has been found to transform a statistically significant no. of anergic patients into positively reacting states.
FR7330085A 1972-08-17 1973-08-17 Transforming anergic cancer patients into allergic state - with 2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole Granted FR2196173A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28136972A 1972-08-17 1972-08-17

Publications (2)

Publication Number Publication Date
FR2196173A1 true FR2196173A1 (en) 1974-03-15
FR2196173B1 FR2196173B1 (en) 1976-09-03

Family

ID=23076992

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7330085A Granted FR2196173A1 (en) 1972-08-17 1973-08-17 Transforming anergic cancer patients into allergic state - with 2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole

Country Status (5)

Country Link
BE (1) BE803719A (en)
DE (1) DE2340633C2 (en)
FR (1) FR2196173A1 (en)
PH (1) PH9905A (en)
ZA (1) ZA735605B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642809A (en) * 1965-10-05 1972-02-15 American Cyanamid Co Method for producing 2 3 5 6-tetra hydroimidazo-(2 1-b)thiazoles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131034C (en) * 1964-05-11

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642809A (en) * 1965-10-05 1972-02-15 American Cyanamid Co Method for producing 2 3 5 6-tetra hydroimidazo-(2 1-b)thiazoles

Also Published As

Publication number Publication date
BE803719A (en) 1973-12-17
FR2196173B1 (en) 1976-09-03
AU5903373A (en) 1975-02-13
DE2340633C2 (en) 1985-09-05
DE2340633A1 (en) 1974-02-28
PH9905A (en) 1976-06-08
ZA735605B (en) 1975-04-30

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