FR2186243A1 - Anthranilic acid derivs - by esterification of 2-(3'-trifluoromethylt -anilino)- benzoic acid - Google Patents
Anthranilic acid derivs - by esterification of 2-(3'-trifluoromethylt -anilino)- benzoic acidInfo
- Publication number
- FR2186243A1 FR2186243A1 FR7219265A FR7219265A FR2186243A1 FR 2186243 A1 FR2186243 A1 FR 2186243A1 FR 7219265 A FR7219265 A FR 7219265A FR 7219265 A FR7219265 A FR 7219265A FR 2186243 A1 FR2186243 A1 FR 2186243A1
- Authority
- FR
- France
- Prior art keywords
- acid
- anthranilic acid
- trifluoromethylt
- anilino
- esterification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical compound NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 title 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Natural products OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 title 1
- 239000005711 Benzoic acid Substances 0.000 title 1
- 235000010233 benzoic acid Nutrition 0.000 title 1
- 230000032050 esterification Effects 0.000 title 1
- 238000005886 esterification reaction Methods 0.000 title 1
- SDGATCBJNWVONW-UHFFFAOYSA-N 2-[3-(trifluoromethylsulfanyl)anilino]benzoic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=CC(SC(F)(F)F)=C1 SDGATCBJNWVONW-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- LPEPZBJOKDYZAD-UHFFFAOYSA-N flufenamic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1 LPEPZBJOKDYZAD-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 230000001562 ulcerogenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7219265A FR2186243A1 (en) | 1972-05-30 | 1972-05-30 | Anthranilic acid derivs - by esterification of 2-(3'-trifluoromethylt -anilino)- benzoic acid |
DE2324799A DE2324799A1 (de) | 1972-05-30 | 1973-05-16 | Neue derivate der 2-aminobenzoesaeure |
ZA733421A ZA733421B (en) | 1972-05-30 | 1973-05-21 | Athranilic acid derivatives |
BE131363A BE799836A (fr) | 1972-05-30 | 1973-05-21 | Nouveaux derives de l'acide amino-2 benzoique |
NL7307190A NL7307190A (en)) | 1972-05-30 | 1973-05-23 | |
AU56046/73A AU5604673A (en) | 1972-05-30 | 1973-05-23 | Anthranilic acid derivatives |
ES415404A ES415404A1 (es) | 1972-05-30 | 1973-05-30 | Procedimiento para preparar derivados del acido amino-2 benzoico. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7219265A FR2186243A1 (en) | 1972-05-30 | 1972-05-30 | Anthranilic acid derivs - by esterification of 2-(3'-trifluoromethylt -anilino)- benzoic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2186243A1 true FR2186243A1 (en) | 1974-01-11 |
FR2186243B1 FR2186243B1 (en)) | 1975-10-17 |
Family
ID=9099302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7219265A Granted FR2186243A1 (en) | 1972-05-30 | 1972-05-30 | Anthranilic acid derivs - by esterification of 2-(3'-trifluoromethylt -anilino)- benzoic acid |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU5604673A (en)) |
BE (1) | BE799836A (en)) |
DE (1) | DE2324799A1 (en)) |
ES (1) | ES415404A1 (en)) |
FR (1) | FR2186243A1 (en)) |
NL (1) | NL7307190A (en)) |
ZA (1) | ZA733421B (en)) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3358019A (en) * | 1956-05-25 | 1967-12-12 | Sandoz Ltd | Nu-(m-benzylthio-phenyl)-anthranilic acid |
-
1972
- 1972-05-30 FR FR7219265A patent/FR2186243A1/fr active Granted
-
1973
- 1973-05-16 DE DE2324799A patent/DE2324799A1/de active Pending
- 1973-05-21 BE BE131363A patent/BE799836A/xx unknown
- 1973-05-21 ZA ZA733421A patent/ZA733421B/xx unknown
- 1973-05-23 NL NL7307190A patent/NL7307190A/xx unknown
- 1973-05-23 AU AU56046/73A patent/AU5604673A/en not_active Expired
- 1973-05-30 ES ES415404A patent/ES415404A1/es not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3358019A (en) * | 1956-05-25 | 1967-12-12 | Sandoz Ltd | Nu-(m-benzylthio-phenyl)-anthranilic acid |
Also Published As
Publication number | Publication date |
---|---|
DE2324799A1 (de) | 1973-12-13 |
NL7307190A (en)) | 1973-12-04 |
ZA733421B (en) | 1974-04-24 |
FR2186243B1 (en)) | 1975-10-17 |
ES415404A1 (es) | 1976-02-16 |
AU5604673A (en) | 1974-11-28 |
BE799836A (fr) | 1973-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |