FR2150792A1 - Sec phosphoric acid esters - inhibitors of prostaglandins - Google Patents
Sec phosphoric acid esters - inhibitors of prostaglandinsInfo
- Publication number
- FR2150792A1 FR2150792A1 FR7229458A FR7229458A FR2150792A1 FR 2150792 A1 FR2150792 A1 FR 2150792A1 FR 7229458 A FR7229458 A FR 7229458A FR 7229458 A FR7229458 A FR 7229458A FR 2150792 A1 FR2150792 A1 FR 2150792A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- phosphoric acid
- prostaglandins
- inhibitors
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003014 phosphoric acid esters Chemical class 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- -1 aliphatic alcohols Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/14—Esters of phosphoric acids containing P(=O)-halide groups
- C07F9/1406—Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-aryl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/242—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyaryl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Cpds. are of formula A - O - - O - B where M = H or a cation; A and B are same or different where one only of R6, R7 and R16 = at the p- or m-posn. to the phosphoric acid ester gp. and where X = CO-Y, -Y-CO- or ketals of these gps. with aliphatic alcohols; Y = straight hydrocarbon chain (2-3C) either satd. or contng. one double bond; and substd. with max. one; alkyl, alkenyl, phenyl or benzyl where the latter two are opt. m- or p-substd. with alkyl, alkoxy, F, Cl, Br or CF3; R3-7 and R16 are same or different H, alkyl, alkenyl, alkoxy, hydroxy, O-CO-alkyl, -O-PO-(OM)2, F, Cl, Br, CF3, CN, NO2, -COOR9, -CHCOOR9, -OCH2COOR9, -CO-alkyl -CON(R8)2, -CH2CON(R8)2, OCH2CON(R8)2- N(R8)2, -NR8-CO-alkyl. -CH2N(R8)2 or -CH2NR8-COalkyl; R8= H or alkyl and R9 = alkyl or M.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3861971A GB1398528A (en) | 1971-08-17 | 1971-08-17 | Pharmaceutically active secondary phosphoric acid esters |
| GB5230371 | 1971-11-10 | ||
| US215671A US3862270A (en) | 1971-08-17 | 1972-01-05 | Secondary phosphoric acid esters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2150792A1 true FR2150792A1 (en) | 1973-04-13 |
| FR2150792B1 FR2150792B1 (en) | 1975-08-08 |
Family
ID=27259519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7229458A Granted FR2150792A1 (en) | 1971-08-17 | 1972-08-17 | Sec phosphoric acid esters - inhibitors of prostaglandins |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS4829750A (en) |
| BE (1) | BE787666A (en) |
| CA (1) | CA996122A (en) |
| ES (1) | ES405893A1 (en) |
| FR (1) | FR2150792A1 (en) |
| NL (1) | NL7211261A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51104396U (en) * | 1975-02-20 | 1976-08-20 | ||
| JPS5336352A (en) * | 1976-09-14 | 1978-04-04 | Matsushita Electric Works Ltd | Electric tooth brush |
| BR112012024919B1 (en) * | 2010-03-30 | 2019-01-02 | Surmodics Inc | degradable binder, method of coating a support surface with a binder to provide the surface with one or more latent reactive groups, support surface and coated medical device |
-
1972
- 1972-08-16 CA CA149,557A patent/CA996122A/en not_active Expired
- 1972-08-16 ES ES405893A patent/ES405893A1/en not_active Expired
- 1972-08-17 BE BE787666A patent/BE787666A/en unknown
- 1972-08-17 FR FR7229458A patent/FR2150792A1/en active Granted
- 1972-08-17 JP JP8242772A patent/JPS4829750A/ja active Pending
- 1972-08-17 NL NL7211261A patent/NL7211261A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES405893A1 (en) | 1976-02-01 |
| NL7211261A (en) | 1973-02-20 |
| FR2150792B1 (en) | 1975-08-08 |
| JPS4829750A (en) | 1973-04-19 |
| BE787666A (en) | 1972-12-18 |
| CA996122A (en) | 1976-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |