FR2140259A1 - Periwinkle sec alkaloid separation - from totals by treating filtrate from vincamine crystals with tartaric acid - Google Patents
Periwinkle sec alkaloid separation - from totals by treating filtrate from vincamine crystals with tartaric acidInfo
- Publication number
- FR2140259A1 FR2140259A1 FR7120467A FR7120467A FR2140259A1 FR 2140259 A1 FR2140259 A1 FR 2140259A1 FR 7120467 A FR7120467 A FR 7120467A FR 7120467 A FR7120467 A FR 7120467A FR 2140259 A1 FR2140259 A1 FR 2140259A1
- Authority
- FR
- France
- Prior art keywords
- vincamine
- periwinkle
- tartaric acid
- totals
- crystals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 title abstract 4
- 229930013930 alkaloid Natural products 0.000 title abstract 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 title abstract 2
- 241000863480 Vinca Species 0.000 title abstract 2
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000706 filtrate Substances 0.000 title abstract 2
- 235000002906 tartaric acid Nutrition 0.000 title abstract 2
- 239000011975 tartaric acid Substances 0.000 title abstract 2
- 229960002726 vincamine Drugs 0.000 title abstract 2
- 150000003797 alkaloid derivatives Chemical class 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
- QMSXPSURJTUZMP-UHFFFAOYSA-N vincine Chemical compound COC1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 QMSXPSURJTUZMP-UHFFFAOYSA-N 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 241000863486 Vinca minor Species 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G5/00—Alkaloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7120467A FR2140259A1 (en) | 1971-06-07 | 1971-06-07 | Periwinkle sec alkaloid separation - from totals by treating filtrate from vincamine crystals with tartaric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7120467A FR2140259A1 (en) | 1971-06-07 | 1971-06-07 | Periwinkle sec alkaloid separation - from totals by treating filtrate from vincamine crystals with tartaric acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2140259A1 true FR2140259A1 (en) | 1973-01-19 |
| FR2140259B1 FR2140259B1 (enExample) | 1974-08-30 |
Family
ID=9078180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7120467A Granted FR2140259A1 (en) | 1971-06-07 | 1971-06-07 | Periwinkle sec alkaloid separation - from totals by treating filtrate from vincamine crystals with tartaric acid |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2140259A1 (enExample) |
-
1971
- 1971-06-07 FR FR7120467A patent/FR2140259A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2140259B1 (enExample) | 1974-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |