FR2101095A1 - Diamine oxidase from human placenta - for treatment of hyperhistamina - Google Patents

Diamine oxidase from human placenta - for treatment of hyperhistamina

Info

Publication number
FR2101095A1
FR2101095A1 FR7030607A FR7030607A FR2101095A1 FR 2101095 A1 FR2101095 A1 FR 2101095A1 FR 7030607 A FR7030607 A FR 7030607A FR 7030607 A FR7030607 A FR 7030607A FR 2101095 A1 FR2101095 A1 FR 2101095A1
Authority
FR
France
Prior art keywords
diamine oxidase
human placenta
diamine
hyperhistamina
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7030607A
Other languages
French (fr)
Other versions
FR2101095B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Merieux SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Priority to FR7030607A priority Critical patent/FR2101095A1/en
Publication of FR2101095A1 publication Critical patent/FR2101095A1/en
Application granted granted Critical
Publication of FR2101095B1 publication Critical patent/FR2101095B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03022—Diamine oxidase (1.4.3.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Therapeutic compsn. comprising a diamine oxidase obtd. from human placenta by virtually complete elimination of haemoglobin and its derivs., the diamine being a mixture of 4 molecular forms with a mol. wt. being a whole multiple of 1 to 4 x 125,000 plus-or-minus 5,000, the diamine oxidase catalysing the oxidation of histamine, putrescine and cadaverine but not phenethylamine and tyramine. Prepd. by fractionation of an acetone-dried placenta sample dissolved in 1% NaCl soln. with ethanol to remove haemoglobin and its derivs.
FR7030607A 1970-08-20 1970-08-20 Diamine oxidase from human placenta - for treatment of hyperhistamina Granted FR2101095A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7030607A FR2101095A1 (en) 1970-08-20 1970-08-20 Diamine oxidase from human placenta - for treatment of hyperhistamina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7030607A FR2101095A1 (en) 1970-08-20 1970-08-20 Diamine oxidase from human placenta - for treatment of hyperhistamina

Publications (2)

Publication Number Publication Date
FR2101095A1 true FR2101095A1 (en) 1972-03-31
FR2101095B1 FR2101095B1 (en) 1974-02-01

Family

ID=9060402

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7030607A Granted FR2101095A1 (en) 1970-08-20 1970-08-20 Diamine oxidase from human placenta - for treatment of hyperhistamina

Country Status (1)

Country Link
FR (1) FR2101095A1 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170880A1 (en) * 1984-07-09 1986-02-12 Emil Underberg Process for the production of aminooxidase-containing material or aminooxidase from microorganisms, such products and their use in the degradation of histamin in food and drinks
WO1990010061A1 (en) * 1989-03-02 1990-09-07 Griffith University Diamine oxidase and assay for rupture of amniotic membrane in pregnant mammals
WO2002043745A2 (en) * 2000-11-29 2002-06-06 Universita' Degli Studi Di Roma 'la Sapienza' Histaminase of vegetable origin for use in the treatment of allergic and septic shock and of allergic asthma
WO2006003213A1 (en) * 2004-07-07 2006-01-12 Albert Missbichler Diaminooxidase-containing pharmaceutical compositions
WO2012127392A1 (en) * 2011-03-18 2012-09-27 Dr Healthcare España, S. L. Composition comprising diamine oxidase for use in the treatment or prevention of fibromyalgia or chronic fatigue syndrome
WO2012127381A1 (en) * 2011-03-18 2012-09-27 Dr Healthcare España, S. L. Topical compositions comprising diaminooxidase for the treatment or prevention of diseases associated with high histamine levels which involve an increase in pain
US9795654B2 (en) 2012-04-18 2017-10-24 Dr Healthcare España, S.L. Diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170880A1 (en) * 1984-07-09 1986-02-12 Emil Underberg Process for the production of aminooxidase-containing material or aminooxidase from microorganisms, such products and their use in the degradation of histamin in food and drinks
WO1990010061A1 (en) * 1989-03-02 1990-09-07 Griffith University Diamine oxidase and assay for rupture of amniotic membrane in pregnant mammals
WO2002043745A2 (en) * 2000-11-29 2002-06-06 Universita' Degli Studi Di Roma 'la Sapienza' Histaminase of vegetable origin for use in the treatment of allergic and septic shock and of allergic asthma
WO2002043745A3 (en) * 2000-11-29 2003-04-10 Univ Roma Histaminase of vegetable origin for use in the treatment of allergic and septic shock and of allergic asthma
US8722038B2 (en) 2000-11-29 2014-05-13 Bruno Mondovi′ Histaminase of vegetable origin for use in the treatment of allergic and septic shock and of allergic asthma
AT503070B1 (en) * 2004-07-07 2007-09-15 Albert Dr Missbichler Cosmetic or pharmaceutical composition useful for treating urticaria, contact allergies and atopic dermatitis comprises a diamino oxidase not of plant origin in the form of a hydrogel
EP1782824A2 (en) 2004-07-07 2007-05-09 Albert Missbichler Diaminooxidase-containing pharmaceutical preparations
EP1782824A3 (en) * 2004-07-07 2007-07-18 Albert Missbichler Diaminooxidase-containing pharmaceutical preparations
AT502098B1 (en) * 2004-07-07 2007-04-15 Albert Dr Missbichler DIAMOND OXIDASE-CONTAINING COMPOSITION
AU2005259167B2 (en) * 2004-07-07 2010-06-03 Sciotec Diagnostic Technologies Gmbh Diaminooxidase-containing pharmaceutical compositions
US8716244B2 (en) 2004-07-07 2014-05-06 Sciotec Diagnostic Technologies Gmbh Diaminooxidase-containing pharmaceutical compositions
WO2006003213A1 (en) * 2004-07-07 2006-01-12 Albert Missbichler Diaminooxidase-containing pharmaceutical compositions
US9364437B2 (en) 2004-07-07 2016-06-14 Sciotec Diagnostic Technologies Gmbh Diaminooxidase-containing pharmaceutical compositions
WO2012127392A1 (en) * 2011-03-18 2012-09-27 Dr Healthcare España, S. L. Composition comprising diamine oxidase for use in the treatment or prevention of fibromyalgia or chronic fatigue syndrome
WO2012127381A1 (en) * 2011-03-18 2012-09-27 Dr Healthcare España, S. L. Topical compositions comprising diaminooxidase for the treatment or prevention of diseases associated with high histamine levels which involve an increase in pain
ES2387973A1 (en) * 2011-03-18 2012-10-04 Dr Healthcare España, S. L. Topical compositions comprising diaminooxidase for the treatment or prevention of diseases associated with high histamine levels which involve an increase in pain
US9795654B2 (en) 2012-04-18 2017-10-24 Dr Healthcare España, S.L. Diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD)

Also Published As

Publication number Publication date
FR2101095B1 (en) 1974-02-01

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