FR2101010A1 - Sparteine mono-and dipyridoxinates and prepn - as tonics for cardiova disorders - Google Patents

Sparteine mono-and dipyridoxinates and prepn - as tonics for cardiova disorders

Info

Publication number
FR2101010A1
FR2101010A1 FR7029039A FR7029039A FR2101010A1 FR 2101010 A1 FR2101010 A1 FR 2101010A1 FR 7029039 A FR7029039 A FR 7029039A FR 7029039 A FR7029039 A FR 7029039A FR 2101010 A1 FR2101010 A1 FR 2101010A1
Authority
FR
France
Prior art keywords
sparteine
mono
dipyridoxinates
cardiova
tonics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7029039A
Other languages
French (fr)
Other versions
FR2101010B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LYOCENTRE
Original Assignee
LYOCENTRE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LYOCENTRE filed Critical LYOCENTRE
Priority to FR7029039A priority Critical patent/FR2101010A1/en
Publication of FR2101010A1 publication Critical patent/FR2101010A1/en
Application granted granted Critical
Publication of FR2101010B1 publication Critical patent/FR2101010B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine

Abstract

Sparteine mono- and di-pyridoxinates of formulae: R = HOCH2-, -CHO or H2N.CH2-. Cpds. are cardiovascular tonic agents in which sparteine synergises the vitamin B6; the B6 in its turn solubilises the sparteine which may then be given parenterally. Administered orally or parenterally for cardiovascular insufficiency. Prepd. by addn. of 1 or 2 moles of the pyridoxine to 1 mole of oily sparteine base.
FR7029039A 1970-08-06 1970-08-06 Sparteine mono-and dipyridoxinates and prepn - as tonics for cardiova disorders Granted FR2101010A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7029039A FR2101010A1 (en) 1970-08-06 1970-08-06 Sparteine mono-and dipyridoxinates and prepn - as tonics for cardiova disorders

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7029039A FR2101010A1 (en) 1970-08-06 1970-08-06 Sparteine mono-and dipyridoxinates and prepn - as tonics for cardiova disorders

Publications (2)

Publication Number Publication Date
FR2101010A1 true FR2101010A1 (en) 1972-03-31
FR2101010B1 FR2101010B1 (en) 1973-12-21

Family

ID=9059886

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7029039A Granted FR2101010A1 (en) 1970-08-06 1970-08-06 Sparteine mono-and dipyridoxinates and prepn - as tonics for cardiova disorders

Country Status (1)

Country Link
FR (1) FR2101010A1 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
US6339085B1 (en) 1999-03-08 2002-01-15 The University Of Manitoba Therapeutics for cardiovascular and related diseases
WO2002004421A2 (en) * 2000-07-07 2002-01-17 Medicure International Inc. Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
US6489345B1 (en) 1999-07-13 2002-12-03 Medicure, Inc. Treatment of diabetes and related pathologies
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6605612B2 (en) 2000-02-29 2003-08-12 Medicure International Inc. Cardioprotective phosohonates and malonates
US6677356B1 (en) 1999-08-24 2004-01-13 Medicure International Inc. Treatment of cardiovascular and related pathologies
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005304220A1 (en) 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
US6339085B1 (en) 1999-03-08 2002-01-15 The University Of Manitoba Therapeutics for cardiovascular and related diseases
US7230009B2 (en) 1999-03-08 2007-06-12 Medicure, Inc. Pyridoxal analogues and methods of treatment
US6890943B2 (en) 1999-03-08 2005-05-10 Medicure Inc. Pyridoxal analogues and methods of treatment
US6489345B1 (en) 1999-07-13 2002-12-03 Medicure, Inc. Treatment of diabetes and related pathologies
US7144892B2 (en) 1999-08-24 2006-12-05 Merrill Lynch Capital Canada Inc. Treatment of cardiovascular and related pathologies
US7132430B2 (en) 1999-08-24 2006-11-07 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7125889B2 (en) 1999-08-24 2006-10-24 Medicure International Inc. Treating of cardiovascular and related pathologies
US6677356B1 (en) 1999-08-24 2004-01-13 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7115626B2 (en) 1999-08-24 2006-10-03 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7148233B2 (en) 1999-08-24 2006-12-12 Merrill Lynch Capital Canada Inc. Treatment of cardiovascular and related pathologies
US7115625B2 (en) 1999-08-24 2006-10-03 Medicure International Inc. Treatment of cardiovascular and related pathologies
US6605612B2 (en) 2000-02-29 2003-08-12 Medicure International Inc. Cardioprotective phosohonates and malonates
US6667315B2 (en) 2000-02-29 2003-12-23 Medicure International Inc. Cardioprotective phosphonates and malonates
US6780997B2 (en) 2000-02-29 2004-08-24 Medicure International Inc. Cardioprotective phosphonates and malonates
US6867215B2 (en) 2000-02-29 2005-03-15 Medicure International Inc. Cardioprotective phosphonates and malonates
US7105673B2 (en) 2000-02-29 2006-09-12 Medicure International Inc. Cardioprotective phosphonates and malonates
US6861439B2 (en) 2000-03-28 2005-03-01 Medicure International, Inc. Treatment of cerebrovascular disease
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6417204B1 (en) 2000-07-07 2002-07-09 Medicure International Inc. Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics
WO2002004421A3 (en) * 2000-07-07 2002-04-04 Medicure Int Inc Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
WO2002004421A2 (en) * 2000-07-07 2002-01-17 Medicure International Inc. Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses

Also Published As

Publication number Publication date
FR2101010B1 (en) 1973-12-21

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Legal Events

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