FR2092706A1 - Dehydrolinalyl carbamate - with sedative and spasmolytic activity - Google Patents

Dehydrolinalyl carbamate - with sedative and spasmolytic activity

Info

Publication number
FR2092706A1
FR2092706A1 FR7021264A FR7021264A FR2092706A1 FR 2092706 A1 FR2092706 A1 FR 2092706A1 FR 7021264 A FR7021264 A FR 7021264A FR 7021264 A FR7021264 A FR 7021264A FR 2092706 A1 FR2092706 A1 FR 2092706A1
Authority
FR
France
Prior art keywords
carbamate
dehydrolinalyl
sedative
gives
spasmolytic activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7021264A
Other languages
French (fr)
Other versions
FR2092706B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MERAM LAB
Original Assignee
MERAM LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MERAM LAB filed Critical MERAM LAB
Priority to FR7021264A priority Critical patent/FR2092706A1/en
Publication of FR2092706A1 publication Critical patent/FR2092706A1/en
Application granted granted Critical
Publication of FR2092706B1 publication Critical patent/FR2092706B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Dehydrolinalyl carbamate, a novel compound, and dehydrolinal itself are useful as spasmolytic and sedative agents, and as potentiators of hypnotic and neuroleptic agents. At 100 mg/kb i.p. in mice they are active as sedatives; 1.75 mu g/ml of either compound gives 50% inhibition of the contraction of the rat dirodenum induced by 0.05 mu g/ml of acetylcholine. Clinical doses of the compounds are from 10 to 1000 mg depending on the individual requirements. Dehydrolinalol treated with phosgene and ammonia, gives the new carbamate.
FR7021264A 1970-06-10 1970-06-10 Dehydrolinalyl carbamate - with sedative and spasmolytic activity Granted FR2092706A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7021264A FR2092706A1 (en) 1970-06-10 1970-06-10 Dehydrolinalyl carbamate - with sedative and spasmolytic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7021264A FR2092706A1 (en) 1970-06-10 1970-06-10 Dehydrolinalyl carbamate - with sedative and spasmolytic activity

Publications (2)

Publication Number Publication Date
FR2092706A1 true FR2092706A1 (en) 1972-01-28
FR2092706B1 FR2092706B1 (en) 1973-08-10

Family

ID=9056950

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7021264A Granted FR2092706A1 (en) 1970-06-10 1970-06-10 Dehydrolinalyl carbamate - with sedative and spasmolytic activity

Country Status (1)

Country Link
FR (1) FR2092706A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1132406A (en) * 1954-04-29 1957-03-11 Pfizer & Co C Improvements in processes for preparing carbamates of tertiary carbinols

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1132406A (en) * 1954-04-29 1957-03-11 Pfizer & Co C Improvements in processes for preparing carbamates of tertiary carbinols

Also Published As

Publication number Publication date
FR2092706B1 (en) 1973-08-10

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Legal Events

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