FR2088231A1 - Brucella bacteria suspension - treatment of tumours - Google Patents

Brucella bacteria suspension - treatment of tumours

Info

Publication number
FR2088231A1
FR2088231A1 FR7019762A FR7019762A FR2088231A1 FR 2088231 A1 FR2088231 A1 FR 2088231A1 FR 7019762 A FR7019762 A FR 7019762A FR 7019762 A FR7019762 A FR 7019762A FR 2088231 A1 FR2088231 A1 FR 2088231A1
Authority
FR
France
Prior art keywords
treatment
tumours
cells
brucella
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7019762A
Other languages
French (fr)
Other versions
FR2088231B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SABOLOVIC DOMAGOG
Original Assignee
SABOLOVIC DOMAGOG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SABOLOVIC DOMAGOG filed Critical SABOLOVIC DOMAGOG
Priority to FR7019762A priority Critical patent/FR2088231A1/en
Publication of FR2088231A1 publication Critical patent/FR2088231A1/en
Application granted granted Critical
Publication of FR2088231B1 publication Critical patent/FR2088231B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

A suspension of inactivated Brucella bacteria (e.g. B. abortus, melitensis or suis) in which 10-50% of the bacterial cells are whole, the remainder being a lysate, are useful in increasing the non-specific immunity of an organism to which it is administered. It is esp. useful in the treatment of tumours. In an example, cells of Brucella abortus B 19 were cultivated on a solid medium for 72 hrs. at 37 degrees C. The bacteria were sepd., washed, suspended in distilled water and inactivated by heating. Ultrasonic treatment ruptured 85% of the cells and finally the suspension could be treated with an antiseptic, such as sodium methiolate. Administration of this to mice (500 mu g dry wt., i.p./mouse) prolonged their life when injected with Erhlichs carcinoma.
FR7019762A 1970-05-29 1970-05-29 Brucella bacteria suspension - treatment of tumours Granted FR2088231A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7019762A FR2088231A1 (en) 1970-05-29 1970-05-29 Brucella bacteria suspension - treatment of tumours

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7019762A FR2088231A1 (en) 1970-05-29 1970-05-29 Brucella bacteria suspension - treatment of tumours

Publications (2)

Publication Number Publication Date
FR2088231A1 true FR2088231A1 (en) 1972-01-07
FR2088231B1 FR2088231B1 (en) 1974-03-22

Family

ID=9056380

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7019762A Granted FR2088231A1 (en) 1970-05-29 1970-05-29 Brucella bacteria suspension - treatment of tumours

Country Status (1)

Country Link
FR (1) FR2088231A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2186235A1 (en) * 1972-05-05 1974-01-11 Pilet Charles Antiviral lysed brucella compns - for treating aphthous fever and Newcastle disease in animals and influenza in man

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6802042A (en) * 1967-02-15 1968-08-16

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6802042A (en) * 1967-02-15 1968-08-16

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2186235A1 (en) * 1972-05-05 1974-01-11 Pilet Charles Antiviral lysed brucella compns - for treating aphthous fever and Newcastle disease in animals and influenza in man

Also Published As

Publication number Publication date
FR2088231B1 (en) 1974-03-22

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Legal Events

Date Code Title Description
ST Notification of lapse