FR2086003A2 - Substd n-hydroxy propargyloxyphenylaceta - mide derivs, anti inflammatories - Google Patents

Substd n-hydroxy propargyloxyphenylaceta - mide derivs, anti inflammatories

Info

Publication number
FR2086003A2
FR2086003A2 FR7044997A FR7044997A FR2086003A2 FR 2086003 A2 FR2086003 A2 FR 2086003A2 FR 7044997 A FR7044997 A FR 7044997A FR 7044997 A FR7044997 A FR 7044997A FR 2086003 A2 FR2086003 A2 FR 2086003A2
Authority
FR
France
Prior art keywords
derivs
substd
hydroxy
propargyloxyphenylaceta
mide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7044997A
Other languages
French (fr)
Other versions
FR2086003B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MADAN AG CH
Original Assignee
MADAN AG CH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MADAN AG CH filed Critical MADAN AG CH
Publication of FR2086003A2 publication Critical patent/FR2086003A2/en
Application granted granted Critical
Publication of FR2086003B2 publication Critical patent/FR2086003B2/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Substd. N-hydroxy propargyloxyphenylacetamide derivs., antiinflammatories Novel cmpds. with anti-inflammatory, analgesic and antipyretic activity have formula (I) and are prepared by reaction of corresponding esters with hydroxylamino: where R1, R2 = H, F, Cl, Br, 1-3C alkyl, 1-3C alkoxy (provided that R1 and R2 not both = H); R3 = H, lower alkyl.
FR7044997A 1965-12-09 1970-12-14 Substd n-hydroxy propargyloxyphenylaceta - mide derivs, anti inflammatories Granted FR2086003A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE21357 1965-12-09
BE35540 1966-11-07
US2800370A 1970-04-13 1970-04-13

Publications (2)

Publication Number Publication Date
FR2086003A2 true FR2086003A2 (en) 1971-12-31
FR2086003B2 FR2086003B2 (en) 1974-08-23

Family

ID=27158370

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7044997A Granted FR2086003A2 (en) 1965-12-09 1970-12-14 Substd n-hydroxy propargyloxyphenylaceta - mide derivs, anti inflammatories

Country Status (2)

Country Link
FR (1) FR2086003A2 (en)
NL (1) NL7017022A (en)

Also Published As

Publication number Publication date
FR2086003B2 (en) 1974-08-23
NL7017022A (en) 1971-06-17

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