FR2068439A6 - 2-ethoxy-5-chlorophenylalkyl dimethylamines diuretics - Google Patents

2-ethoxy-5-chlorophenylalkyl dimethylamines diuretics

Info

Publication number
FR2068439A6
FR2068439A6 FR6940113A FR6940113A FR2068439A6 FR 2068439 A6 FR2068439 A6 FR 2068439A6 FR 6940113 A FR6940113 A FR 6940113A FR 6940113 A FR6940113 A FR 6940113A FR 2068439 A6 FR2068439 A6 FR 2068439A6
Authority
FR
France
Prior art keywords
ethoxy
chlorophenylalkyl
dimethylamines
diuretics
cpds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR6940113A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR6940113A priority Critical patent/FR2068439A6/en
Application granted granted Critical
Publication of FR2068439A6 publication Critical patent/FR2068439A6/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

2-Ethoxy-5-chlorophenylalkyl dimethylamines, diuretics New cpds. of formula (I) (where R is straight chain 1-5C alkyl, branched 3-5C alkyl or 5-6C cycloalkyl). The cpds. are prepd. by the LiAlH4 reduction of the corresp. dimethyl amides. Cpds. exhibit diuretic activity. In an example N, N-dimethyl 2-(5-chloro-2-ethoxy) phenyl pentenamide was treated with LiAlH4 in a mixture of ether and THF, to give a 40% yield of (I) (R=nC3H7).
FR6940113A 1969-11-21 1969-11-21 2-ethoxy-5-chlorophenylalkyl dimethylamines diuretics Expired FR2068439A6 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6940113A FR2068439A6 (en) 1969-11-21 1969-11-21 2-ethoxy-5-chlorophenylalkyl dimethylamines diuretics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6940113A FR2068439A6 (en) 1969-11-21 1969-11-21 2-ethoxy-5-chlorophenylalkyl dimethylamines diuretics

Publications (1)

Publication Number Publication Date
FR2068439A6 true FR2068439A6 (en) 1971-08-27

Family

ID=9043420

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6940113A Expired FR2068439A6 (en) 1969-11-21 1969-11-21 2-ethoxy-5-chlorophenylalkyl dimethylamines diuretics

Country Status (1)

Country Link
FR (1) FR2068439A6 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011096897A1 (en) * 2010-02-02 2011-08-11 Agency For Science, Technology And Research Functionalised antifouling compounds and use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3397272A (en) * 1963-06-27 1968-08-13 Geigy Chem Corp Cycloalkyl benzylamine and anorexigenic compositions and method of use
FR1553148A (en) * 1966-12-13 1969-01-10

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3397272A (en) * 1963-06-27 1968-08-13 Geigy Chem Corp Cycloalkyl benzylamine and anorexigenic compositions and method of use
FR1553148A (en) * 1966-12-13 1969-01-10

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011096897A1 (en) * 2010-02-02 2011-08-11 Agency For Science, Technology And Research Functionalised antifouling compounds and use thereof
US9169223B2 (en) 2010-02-02 2015-10-27 Agency For Science, Technology And Research Functionalised antifouling compounds and use thereof
US9938415B2 (en) 2010-02-02 2018-04-10 Agency For Science, Technology And Research Functionalised antifouling compounds and use thereof

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