FR2068423A1 - 3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics - Google Patents

3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics

Info

Publication number
FR2068423A1
FR2068423A1 FR6938134A FR6938134A FR2068423A1 FR 2068423 A1 FR2068423 A1 FR 2068423A1 FR 6938134 A FR6938134 A FR 6938134A FR 6938134 A FR6938134 A FR 6938134A FR 2068423 A1 FR2068423 A1 FR 2068423A1
Authority
FR
France
Prior art keywords
antiarrhythmics
oxazolidinones
ethoxycarbonyl
phenyl
phosgene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6938134A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR6938134A priority Critical patent/FR2068423A1/en
Publication of FR2068423A1 publication Critical patent/FR2068423A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems

Abstract

3-Phenyl-5-ethoxycarbonyl-2-oxazolidinones-antiarrhythmics. Oxazolidinone derivs have formula (I) where R1 and R2=1-4C aliphatic grps. or together with the C atom to which they are attached form a 5-8C cycloalkyl gp. The cpds. are prepd. from a ketone R1-CO-R2 by reaction with ethyl chloroacetate to give an alpha-carbethoxy epoxide followed by treatment with aniline and cyclisation with phosgene. In example acetaone and ethyl chloracetate were reacted together in the presence of K, tert, butoxide, the product treated with excess aniline then with phosgene to give (I) R1=R2=CH3, m.pt. 85 degrees C.
FR6938134A 1969-11-06 1969-11-06 3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics Withdrawn FR2068423A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6938134A FR2068423A1 (en) 1969-11-06 1969-11-06 3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6938134A FR2068423A1 (en) 1969-11-06 1969-11-06 3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics

Publications (1)

Publication Number Publication Date
FR2068423A1 true FR2068423A1 (en) 1971-08-27

Family

ID=9042680

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6938134A Withdrawn FR2068423A1 (en) 1969-11-06 1969-11-06 3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics

Country Status (1)

Country Link
FR (1) FR2068423A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0417044A2 (en) * 1989-09-07 1991-03-13 Ciba-Geigy Ag Oxazolidinones and thiones as plantgrowth regulators
EP0697408A1 (en) * 1994-08-19 1996-02-21 MERCK PATENT GmbH 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists
US7645781B2 (en) 2002-02-25 2010-01-12 Pfizer Inc N-aryl-2-oxazolidinone-5-carboxamides and their derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2437390A (en) * 1948-03-09 Z-oxazolidone compounds and proc

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2437390A (en) * 1948-03-09 Z-oxazolidone compounds and proc

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0417044A2 (en) * 1989-09-07 1991-03-13 Ciba-Geigy Ag Oxazolidinones and thiones as plantgrowth regulators
EP0417044A3 (en) * 1989-09-07 1991-06-12 Ciba-Geigy Ag Oxazolidinones and thiones as plantgrowth regulators
EP0697408A1 (en) * 1994-08-19 1996-02-21 MERCK PATENT GmbH 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists
US7645781B2 (en) 2002-02-25 2010-01-12 Pfizer Inc N-aryl-2-oxazolidinone-5-carboxamides and their derivatives

Similar Documents

Publication Publication Date Title
GB1153196A (en) Method of Dyeing Hair
SE378607B (en) METHOD OF PREPARING POLYURETHANE ELASTOMERS THROUGH TREATMENT OF HIGH MOLECULAR AND LOW MOLECULAR POLYHUDROXYL COMPOUNDS WITH DIISOCYANATES, WARP THE OBTAINED PRODUCT WAS REAGERATED WITH ESTERGERAPH ARHATERPHARPH.
FR1352357A (en) Tert-alkoxyalkyl esters, their polymers and processes for the preparation of these products
FR1321077A (en) Process for the preparation of low molecular weight copolymers containing hydroxyl groups
FR2068423A1 (en) 3-phenyl-5-ethoxycarbonyl-2-oxazolidinones antiarrhythmics
FR2033086A5 (en) Silicone polymers with threee dimensional cross - links
NL7414429A (en) TREATMENT OF DISPERSIONS OF SMALL DROPS.
FR1390201A (en) Polymers having hydroxyl functional groups, and processes for preparing said polymers
NL7414430A (en) TREATMENT OF DISPERSIONS OF SMALL DROPS.
ES380854A1 (en) A-phenylsuccinimido-halo-sulphonamido-benzenes
ES412135A1 (en) Process for the manufacture of 2-aryl-v-triazole
ES279932A1 (en) Procedure for preparing colorants of the naftofurandiºnica series (Machine-translation by Google Translate, not legally binding)
CA693056A (en) Process for the production of stretched formed bodies from high molecular weight, linear polycarbonates
GB1045819A (en) New isoxazoles and process for preparing same
GB982108A (en) Process for treating solid polymers
FR2128678A1 (en) Electrolytic cell - for sterilising drinking water or water for swimming baths
ES421508A1 (en) 1,4-Bis-(5{40 -nitroimidazolyl-2{40 -methylene-imino)-piperazines
ES275784A3 (en) Procedure for the synthesis of a new chemotherapic product (Machine-translation by Google Translate, not legally binding)
NL155273B (en) PROCESS FOR PREPARING POLYISOPRENE BY POLYMERIZATION OF ISOPRENE WITH A CATALYST OBTAINED FROM TITANIUM TRACHLORIDE, TRIALKYLALUMINUM AND A MONOAMINE.
CH486403A (en) Process for the production of allyl chloride and its monomethyl substitution products on supported catalysts
ES289226A1 (en) Procedure for the preparation of new diamines (Machine-translation by Google Translate, not legally binding)
CA637769A (en) Process for the production of vitamins of the b12 group by means of propioni bacteria
ES376752A1 (en) Process for the preparation of trichloroethylene
FR2215215A1 (en) 3-alkylaminocarbonyl-1,3-oxazolidin-2-ones - antispasmodics, antiinflammatories, antidepressants, anxiolytics and sedatives
FR1366699A (en) Process for the preparation of low molecular weight polydienes

Legal Events

Date Code Title Description
ST Notification of lapse