FR2068417A1 - Diester of 2-methyl-4,4-dihydroxymethyloxazoline with substd propioni - antilipaemic agent - Google Patents

Diester of 2-methyl-4,4-dihydroxymethyloxazoline with substd propioni - antilipaemic agent

Info

Publication number
FR2068417A1
FR2068417A1 FR6936759A FR6936759A FR2068417A1 FR 2068417 A1 FR2068417 A1 FR 2068417A1 FR 6936759 A FR6936759 A FR 6936759A FR 6936759 A FR6936759 A FR 6936759A FR 2068417 A1 FR2068417 A1 FR 2068417A1
Authority
FR
France
Prior art keywords
methyl
antilipaemic
agent
substd
diester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6936759A
Other languages
French (fr)
Other versions
FR2068417B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR6936759A priority Critical patent/FR2068417A1/en
Publication of FR2068417A1 publication Critical patent/FR2068417A1/en
Application granted granted Critical
Publication of FR2068417B1 publication Critical patent/FR2068417B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Diester of 2-methyl-4, 4-dihydroxymethyl-oxazoline with substd. propionic acid; antilipaemic agent. A cpd. of formula: is useful as an antilipaemic, and esp. an anti-cholestero-laemic, agent, and as a synthetic intermediate. It is prepd. by treating 2-methyl-4,4-dihydroxymethyl-oxazoline with 2-p-chlorophenoxy-2-methyl-propionyl chloride, in the presence of pyridine or NN-dimethyl-aniline, in dioxan, ethyl acetate or chloroform as solvent.
FR6936759A 1969-10-27 1969-10-27 Diester of 2-methyl-4,4-dihydroxymethyloxazoline with substd propioni - antilipaemic agent Granted FR2068417A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6936759A FR2068417A1 (en) 1969-10-27 1969-10-27 Diester of 2-methyl-4,4-dihydroxymethyloxazoline with substd propioni - antilipaemic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6936759A FR2068417A1 (en) 1969-10-27 1969-10-27 Diester of 2-methyl-4,4-dihydroxymethyloxazoline with substd propioni - antilipaemic agent

Publications (2)

Publication Number Publication Date
FR2068417A1 true FR2068417A1 (en) 1971-08-27
FR2068417B1 FR2068417B1 (en) 1973-01-12

Family

ID=9042098

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6936759A Granted FR2068417A1 (en) 1969-10-27 1969-10-27 Diester of 2-methyl-4,4-dihydroxymethyloxazoline with substd propioni - antilipaemic agent

Country Status (1)

Country Link
FR (1) FR2068417A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2181799A1 (en) * 1972-03-08 1973-12-07 Merck & Co Inc

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1466208A (en) * 1959-10-02 1967-01-20 Aspro Nicholas Ltd New oxazoline derivatives and process for their preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1466208A (en) * 1959-10-02 1967-01-20 Aspro Nicholas Ltd New oxazoline derivatives and process for their preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2181799A1 (en) * 1972-03-08 1973-12-07 Merck & Co Inc

Also Published As

Publication number Publication date
FR2068417B1 (en) 1973-01-12

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Legal Events

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CD Change of name or company name
ST Notification of lapse