FR2035783A1 - (A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lowe - Google Patents

(A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lowe

Info

Publication number
FR2035783A1
FR2035783A1 FR6909072A FR6909072A FR2035783A1 FR 2035783 A1 FR2035783 A1 FR 2035783A1 FR 6909072 A FR6909072 A FR 6909072A FR 6909072 A FR6909072 A FR 6909072A FR 2035783 A1 FR2035783 A1 FR 2035783A1
Authority
FR
France
Prior art keywords
cpds
aryl
formula
acid addition
addition salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6909072A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
McNeil Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeilab Inc, McNeil Laboratories Inc filed Critical McNeilab Inc
Priority to FR6909072A priority Critical patent/FR2035783A1/en
Publication of FR2035783A1 publication Critical patent/FR2035783A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

(A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lower alkyl (R=H when R1=lower alkanoyl), R1=H or lower alkanoyl, aryl=Ph, halophenyl(halogen having at no.80), lower alkylphenyl, lower alkoxyphenyl or m-trifluoromethylphenyl (z=2, R=R1=H, n=4 when aryl =m-trifluoromethylphenyl) (B) Cpds. of formula (II) where x=3 or 4, m=1 or 2 Ar=Ph, halophenyl (halogen having at no. 80) lower alkylphenyl or lower alkoxyphenyl (Ar is not = lower alkoxyphenyl when x=4). (C) Cpds. of formulae (III) and (IV) where n=4 or 5, m=1 or 2 Ar=Ph, halophenyl (halogen having at no.80) lower alkylphenyl or lower alkoxyphenyl.
FR6909072A 1969-03-27 1969-03-27 (A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lowe Withdrawn FR2035783A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6909072A FR2035783A1 (en) 1969-03-27 1969-03-27 (A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lowe

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6909072A FR2035783A1 (en) 1969-03-27 1969-03-27 (A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lowe

Publications (1)

Publication Number Publication Date
FR2035783A1 true FR2035783A1 (en) 1970-12-24

Family

ID=9031359

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6909072A Withdrawn FR2035783A1 (en) 1969-03-27 1969-03-27 (A) Cpds. of formula I and their therapeutically active acid addition salts: where n=4 or 5 z=1, 2 or 3 (aryl=Ph, R=R1=H, n=4 when z=3), R=H or lowe

Country Status (1)

Country Link
FR (1) FR2035783A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

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