FR2034536A1 - Thiazolidinecarboxylic acid-4derivs - Google Patents

Thiazolidinecarboxylic acid-4derivs

Info

Publication number
FR2034536A1
FR2034536A1 FR7004796A FR7004796A FR2034536A1 FR 2034536 A1 FR2034536 A1 FR 2034536A1 FR 7004796 A FR7004796 A FR 7004796A FR 7004796 A FR7004796 A FR 7004796A FR 2034536 A1 FR2034536 A1 FR 2034536A1
Authority
FR
France
Prior art keywords
prepns
derivs
alkoxycarbonyl
biologically
aliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7004796A
Other languages
French (fr)
Other versions
FR2034536B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACADEMIA REPUBL ROMAN A
Original Assignee
ACADEMIA REPUBL ROMAN A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACADEMIA REPUBL ROMAN A filed Critical ACADEMIA REPUBL ROMAN A
Publication of FR2034536A1 publication Critical patent/FR2034536A1/en
Application granted granted Critical
Publication of FR2034536B1 publication Critical patent/FR2034536B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Thiaxolidenecarboxylic acid-4 derivs. New cpds. have general formulae (I) and (II): (where R1 = N, a functional deriv. of hydrazine, H or an aliphatic-, araliphatic-, aromatic- or heterocyclic gp.; R2 = carbamido, alkoxycarbonyl or CN; R'1 = N or an opt. substd. aliphatic gp.; R'2 = carboxyl, carboxyamido, alkoxycarbonyl or CN; R3 = a residue of a biologically-active cpd.) Prepns. against hepatitis consist of aqs. solns., emulsions, suspensions or tablets contg. biologically-active components in combination with thiazolidinecarboxylic acid, its salts or derivs. of formulae (I) and (II). Prepns. are suitable for the treatment of liver disorders and hepatitis etc., and increase the resistance of the organ against ailments.
FR7004796A 1969-02-11 1970-02-11 Thiazolidinecarboxylic acid-4derivs Granted FR2034536A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RO5903969 1969-02-11
RO5904069 1969-02-11

Publications (2)

Publication Number Publication Date
FR2034536A1 true FR2034536A1 (en) 1970-12-11
FR2034536B1 FR2034536B1 (en) 1974-08-30

Family

ID=26653496

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7004796A Granted FR2034536A1 (en) 1969-02-11 1970-02-11 Thiazolidinecarboxylic acid-4derivs

Country Status (1)

Country Link
FR (1) FR2034536A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204411A1 (en) * 1972-11-02 1974-05-24 Claude Dufour
FR2367069A1 (en) * 1976-10-09 1978-05-05 Degussa Pure D,L-cysteine prodn. - by reaction of 2-substd.-thiazoline with hydrogen cyanide to give thiazolidine-4-carbo:nitrile and reaction with aq. mineral acid
EP0057942A2 (en) * 1981-02-11 1982-08-18 Cornell Research Foundation Cysteine delivery system
US4579976A (en) * 1983-12-13 1986-04-01 Atochem Catalytic process for the preparation of trifluoroacetaldehyde

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE661960A (en) * 1964-04-07 1965-08-02

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE661960A (en) * 1964-04-07 1965-08-02

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204411A1 (en) * 1972-11-02 1974-05-24 Claude Dufour
FR2367069A1 (en) * 1976-10-09 1978-05-05 Degussa Pure D,L-cysteine prodn. - by reaction of 2-substd.-thiazoline with hydrogen cyanide to give thiazolidine-4-carbo:nitrile and reaction with aq. mineral acid
EP0057942A2 (en) * 1981-02-11 1982-08-18 Cornell Research Foundation Cysteine delivery system
EP0057942A3 (en) * 1981-02-11 1982-10-27 Cornell Research Foundation Cysteine delivery system
US4579976A (en) * 1983-12-13 1986-04-01 Atochem Catalytic process for the preparation of trifluoroacetaldehyde

Also Published As

Publication number Publication date
FR2034536B1 (en) 1974-08-30

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