FR2026223A1 - 1-(2,6-dimethylbenzylidene-amino)-3-hydroxy - guanidine - Google Patents

1-(2,6-dimethylbenzylidene-amino)-3-hydroxy - guanidine

Info

Publication number
FR2026223A1
FR2026223A1 FR6943107A FR6943107A FR2026223A1 FR 2026223 A1 FR2026223 A1 FR 2026223A1 FR 6943107 A FR6943107 A FR 6943107A FR 6943107 A FR6943107 A FR 6943107A FR 2026223 A1 FR2026223 A1 FR 2026223A1
Authority
FR
France
Prior art keywords
guanidine
hydroxy
amino
alkyl
dimethylbenzylidene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6943107A
Other languages
French (fr)
Other versions
FR2026223B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2026223A1 publication Critical patent/FR2026223A1/en
Application granted granted Critical
Publication of FR2026223B1 publication Critical patent/FR2026223B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones

Abstract

Title compd. (I) and its acid addition salts are new and useful a hypo-tensive and hypoglycaemic agent is prepd. by reacting either 2,6-dimethylbenzaldehyde S-alkyl-isothio-semicarbazone (II) with NH2OH or 2,6-dimethylbenzaldehyde with 1-amino-3-hydroxy-guanidine. (II) can be prepared from the aldehyde and the S-alkyl-thiosemicarbazide or from the corresponding semicarbazone (III) and an alkyl halide, (III) being prepd. from semicarbazide and the aldehyde.
FR6943107A 1968-12-16 1969-12-12 1-(2,6-dimethylbenzylidene-amino)-3-hydroxy - guanidine Granted FR2026223A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78427068A 1968-12-16 1968-12-16
US81369769A 1969-04-04 1969-04-04
US84237469A 1969-07-16 1969-07-16

Publications (2)

Publication Number Publication Date
FR2026223A1 true FR2026223A1 (en) 1970-09-18
FR2026223B1 FR2026223B1 (en) 1973-07-13

Family

ID=27419811

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6943107A Granted FR2026223A1 (en) 1968-12-16 1969-12-12 1-(2,6-dimethylbenzylidene-amino)-3-hydroxy - guanidine

Country Status (9)

Country Link
JP (1) JPS4816911B1 (en)
BE (1) BE743151A (en)
CA (1) CA959859A (en)
CH (1) CH523232A (en)
DE (1) DE1962149A1 (en)
ES (2) ES374564A1 (en)
FR (1) FR2026223A1 (en)
IL (1) IL33539A0 (en)
NL (1) NL6918413A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49128311U (en) * 1973-03-01 1974-11-02
JPS5698462U (en) * 1979-12-27 1981-08-04
JPS6220849U (en) * 1985-07-23 1987-02-07

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE958832C (en) * 1952-11-14 1957-02-28 Bayer Ag Process for the preparation of guanylhydrazones
NL6814608A (en) * 1967-10-13 1969-04-15
NL6818769A (en) * 1968-01-22 1969-07-24

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE958832C (en) * 1952-11-14 1957-02-28 Bayer Ag Process for the preparation of guanylhydrazones
NL6814608A (en) * 1967-10-13 1969-04-15
NL6818769A (en) * 1968-01-22 1969-07-24

Also Published As

Publication number Publication date
ES398668A1 (en) 1975-06-01
IL33539A0 (en) 1970-02-19
CH523232A (en) 1972-05-31
ES374564A1 (en) 1972-04-01
BE743151A (en) 1970-06-15
JPS4816911B1 (en) 1973-05-25
DE1962149A1 (en) 1970-07-02
NL6918413A (en) 1970-06-18
FR2026223B1 (en) 1973-07-13
CA959859A (en) 1974-12-24

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Legal Events

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