FR2010136A2 - Nouveaux medicaments anti-tumeur - Google Patents
Nouveaux medicaments anti-tumeurInfo
- Publication number
- FR2010136A2 FR2010136A2 FR6918413A FR6918413A FR2010136A2 FR 2010136 A2 FR2010136 A2 FR 2010136A2 FR 6918413 A FR6918413 A FR 6918413A FR 6918413 A FR6918413 A FR 6918413A FR 2010136 A2 FR2010136 A2 FR 2010136A2
- Authority
- FR
- France
- Prior art keywords
- salt
- pref
- mycophenolic acid
- mercaptopurine
- cpd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 229960003444 immunosuppressant agent Drugs 0.000 title abstract 2
- 230000001861 immunosuppressant effect Effects 0.000 title abstract 2
- 239000003018 immunosuppressive agent Substances 0.000 title abstract 2
- GLVAUDGFNGKCSF-UHFFFAOYSA-N mercaptopurine Chemical compound S=C1NC=NC2=C1NC=N2 GLVAUDGFNGKCSF-UHFFFAOYSA-N 0.000 abstract 6
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 abstract 4
- 229960000951 mycophenolic acid Drugs 0.000 abstract 4
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 229960001428 mercaptopurine Drugs 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2656268 | 1968-06-04 | ||
| GB968969A GB1203328A (en) | 1968-06-04 | 1968-06-04 | Pharmaceutical compositions |
| GB4928368 | 1968-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2010136A2 true FR2010136A2 (fr) | 1970-02-13 |
Family
ID=27255411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6918413A Withdrawn FR2010136A2 (fr) | 1968-06-04 | 1969-06-04 | Nouveaux medicaments anti-tumeur |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE733669A (enrdf_load_stackoverflow) |
| DE (1) | DE1928518A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2010136A2 (enrdf_load_stackoverflow) |
| NL (1) | NL6908349A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443435A (en) * | 1980-04-21 | 1984-04-17 | Merck & Co., Inc. | Prodrugs of 6-mercaptopurine and 6-mercaptopurine ribosides and therapeutic compositions and methods employing them |
| WO1988001870A1 (en) * | 1986-09-15 | 1988-03-24 | Sterling Institute | Therapeutic treatment for arthritic conditions |
-
1969
- 1969-05-27 BE BE733669D patent/BE733669A/xx unknown
- 1969-06-02 NL NL6908349A patent/NL6908349A/xx unknown
- 1969-06-04 FR FR6918413A patent/FR2010136A2/fr not_active Withdrawn
- 1969-06-04 DE DE19691928518 patent/DE1928518A1/de active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443435A (en) * | 1980-04-21 | 1984-04-17 | Merck & Co., Inc. | Prodrugs of 6-mercaptopurine and 6-mercaptopurine ribosides and therapeutic compositions and methods employing them |
| WO1988001870A1 (en) * | 1986-09-15 | 1988-03-24 | Sterling Institute | Therapeutic treatment for arthritic conditions |
| US4853373A (en) * | 1986-09-15 | 1989-08-01 | Livingston William S | Therapeutic treatment for arthritic condition |
Also Published As
| Publication number | Publication date |
|---|---|
| BE733669A (enrdf_load_stackoverflow) | 1969-11-27 |
| NL6908349A (enrdf_load_stackoverflow) | 1969-12-08 |
| DE1928518A1 (de) | 1970-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Withdrawal of published application |