FR19C1043I1 - - Google Patents

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Publication number
FR19C1043I1
FR19C1043I1 FR19C1043C FR19C1043I1 FR 19C1043 I1 FR19C1043 I1 FR 19C1043I1 FR 19C1043 C FR19C1043 C FR 19C1043C FR 19C1043 I1 FR19C1043 I1 FR 19C1043I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR19C1043I1 publication Critical patent/FR19C1043I1/fr
Application granted granted Critical
Publication of FR19C1043I2 publication Critical patent/FR19C1043I2/en
Active legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
FR19C1043C 2007-07-31 2019-06-28 PHARMACEUTICAL COMPOSITION CONTAINING AN OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE Active FR19C1043I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007198590 2007-07-31
PCT/JP2008/063541 WO2009017098A1 (en) 2007-07-31 2008-07-29 Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity and intermediate thereof

Publications (2)

Publication Number Publication Date
FR19C1043I1 true FR19C1043I1 (en) 2019-08-09
FR19C1043I2 FR19C1043I2 (en) 2020-04-03

Family

ID=40304328

Family Applications (1)

Application Number Title Priority Date Filing Date
FR19C1043C Active FR19C1043I2 (en) 2007-07-31 2019-06-28 PHARMACEUTICAL COMPOSITION CONTAINING AN OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE

Country Status (21)

Country Link
US (2) US8530668B2 (en)
EP (1) EP2184279B1 (en)
JP (1) JP5164181B2 (en)
KR (1) KR20100027243A (en)
CN (4) CN103393678A (en)
AU (1) AU2008283357B2 (en)
BR (1) BRPI0814891A2 (en)
CA (1) CA2694567C (en)
CY (1) CY1116190T1 (en)
DK (1) DK2184279T3 (en)
ES (1) ES2528196T3 (en)
FR (1) FR19C1043I2 (en)
HR (1) HRP20150062T1 (en)
MX (1) MX2010001082A (en)
NL (1) NL300998I2 (en)
PL (1) PL2184279T3 (en)
PT (1) PT2184279E (en)
RU (1) RU2476429C2 (en)
SI (1) SI2184279T1 (en)
TW (1) TWI422371B (en)
WO (1) WO2009017098A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI564008B (en) * 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 Formulation for solubility enhancement of poorly soluble drugs
JP6202620B2 (en) * 2012-06-29 2017-09-27 塩野義製薬株式会社 Pharmaceutical composition containing a compound having thrombopoietin receptor agonist activity
US20140047572A1 (en) * 2012-08-13 2014-02-13 University Of Rochester Thrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury
CN105992761A (en) * 2013-12-20 2016-10-05 盐野义制药株式会社 Methods respectively for producing optically active compound having agonistic activity on thrombopoietin receptors and intermediate of said compound
CN105412930A (en) * 2015-08-07 2016-03-23 军事医学科学院华南干细胞与再生医学研究中心 Application of TPO (thrombopoietin) receptor agonist in promoting homing of HSCs (hematopoietic stem cells)
JP6168579B1 (en) * 2016-02-12 2017-07-26 塩野義製薬株式会社 Platelet production promoter containing Rustrombopag for patients with severe liver dysfunction
CN106083759B (en) * 2016-06-15 2022-02-15 上海丸全化学科技有限公司 Brand-new synthesis process of lutofopa
EP3511332A4 (en) * 2016-09-08 2020-03-25 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Novel 2-acylaminothiazole derivative and preparation method therefor and use thereof
CN106565625B (en) * 2016-11-04 2018-01-30 杭州励德生物科技有限公司 A kind of antiplatelet reduces the preparation method of disease new drug Lusutrombopag intermediates
CN109311831B (en) * 2017-02-14 2021-07-09 四川科伦药物研究院有限公司 Crystal form of 4-phenylthiazole derivative and preparation method thereof
CN109970678B (en) * 2017-12-28 2024-03-08 四川科伦药物研究院有限公司 Amorphous 4-phenylthiazole derivative, and preparation method and application thereof
ES2953320T3 (en) * 2018-06-08 2023-11-10 Sichuan Kelun Pharm Res Inst Co Ltd Crystalline form of 4-phenylthiazole derivative and method of preparation thereof
CN113164455A (en) * 2018-12-04 2021-07-23 盐野义制药株式会社 Solid dispersion of poorly soluble drug

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
EP1961760A3 (en) * 1995-06-07 2008-09-03 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
JPH1072492A (en) 1996-09-02 1998-03-17 Hokuriku Seiyaku Co Ltd Peptide compound
JPH10287634A (en) 1997-04-11 1998-10-27 Otsuka Pharmaceut Co Ltd Benzene derivatives
JPH111477A (en) 1997-06-12 1999-01-06 Hokuriku Seiyaku Co Ltd 1,4-benzodiazepine and use thereof
JPH11152276A (en) 1997-11-20 1999-06-08 Hokuriku Seiyaku Co Ltd Benzodiazepine derivative
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
GC0000177A (en) * 1998-12-17 2006-03-29 Smithkline Beecham Thrombopoietin mimetics
US7026334B1 (en) 1999-07-26 2006-04-11 Shionogi & Co., Ltd. Thiazolidine compounds and pharmaceutical compositions exhibiting thrombopoietin receptor agonism
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
EP1354880A4 (en) 2001-01-26 2004-08-25 Shionogi & Co Halogen compounds having thrombopoietin receptor agonism
WO2002059099A1 (en) 2001-01-26 2002-08-01 Shionogi & Co., Ltd. Cyclic compounds having thrombopoietin receptor agonism
US20040077697A1 (en) 2001-02-02 2004-04-22 Hiroyuki Koshio 2-Acylaminothiazole derivative or its salt
KR101010905B1 (en) 2002-01-18 2011-01-25 아스텔라스세이야쿠 가부시키가이샤 2-acylaminothiazole derivavtive or salt thereof
JP4317818B2 (en) 2002-09-30 2009-08-19 アステラス製薬株式会社 Novel salt of 2-acylaminothiazole derivative
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
FR2854158B1 (en) * 2003-04-25 2006-11-17 Sanofi Synthelabo 2-ACYLAMINO-4-PHENYLETHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
MXPA06000441A (en) 2003-07-17 2006-04-05 Astellas Pharma Inc 2-acylaminothiazole derivative or salt thereof.
AU2004263442B2 (en) * 2003-08-12 2008-05-29 Shionogi & Co., Ltd. Compounds having thrombopoietin receptor agonism
ZA200602755B (en) * 2003-09-06 2007-06-27 Vertex Pharma Modulators of ATP-binding cassette transporters
JP4665769B2 (en) 2005-01-12 2011-04-06 アステラス製薬株式会社 Method for producing acylaminothiazole derivative
JP4774995B2 (en) 2005-01-12 2011-09-21 アステラス製薬株式会社 Pharmaceutical composition comprising an acylaminothiazole derivative as an active ingredient
WO2007004038A1 (en) 2005-07-05 2007-01-11 Pfizer Products Inc. Aminothiazole derivatives as agonists of the thrombopoietin receptor
US8515798B2 (en) 2005-09-27 2013-08-20 Accenture Global Services Gmbh Closed-loop supply chain in the paper packaging sector
CN101355968A (en) 2005-11-08 2009-01-28 安斯泰来制药有限公司 Compositions and methods for treating thrombocytopenia

Also Published As

Publication number Publication date
TWI422371B (en) 2014-01-11
AU2008283357B2 (en) 2011-08-11
AU2008283357A1 (en) 2009-02-05
EP2184279A1 (en) 2010-05-12
FR19C1043I2 (en) 2020-04-03
CA2694567A1 (en) 2009-02-05
CN101809008A (en) 2010-08-18
CY1116190T1 (en) 2017-02-08
DK2184279T3 (en) 2015-01-26
US20100267783A1 (en) 2010-10-21
RU2010107169A (en) 2011-09-10
EP2184279A4 (en) 2011-11-02
US8530668B2 (en) 2013-09-10
PT2184279E (en) 2015-02-05
CN103396313B (en) 2015-05-13
CN101809008B (en) 2013-09-18
SI2184279T1 (en) 2015-04-30
NL300998I2 (en) 2019-08-28
KR20100027243A (en) 2010-03-10
NL300998I1 (en) 2019-07-03
JPWO2009017098A1 (en) 2010-10-21
EP2184279B1 (en) 2014-11-12
JP5164181B2 (en) 2013-03-13
RU2476429C2 (en) 2013-02-27
WO2009017098A1 (en) 2009-02-05
MX2010001082A (en) 2010-03-01
TW200914000A (en) 2009-04-01
HRP20150062T1 (en) 2015-04-10
CN103450110B (en) 2015-12-09
PL2184279T3 (en) 2015-04-30
US8889722B2 (en) 2014-11-18
BRPI0814891A2 (en) 2015-08-18
CN103396313A (en) 2013-11-20
CA2694567C (en) 2013-04-23
US20130217885A1 (en) 2013-08-22
ES2528196T3 (en) 2015-02-05
CN103393678A (en) 2013-11-20
CN103450110A (en) 2013-12-18

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