FR16C1025I1 - 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile salt - Google Patents

4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile salt

Info

Publication number
FR16C1025I1
FR16C1025I1 FR16C1025C FR16C1025C FR16C1025I1 FR 16C1025 I1 FR16C1025 I1 FR 16C1025I1 FR 16C1025 C FR16C1025 C FR 16C1025C FR 16C1025 C FR16C1025 C FR 16C1025C FR 16C1025 I1 FR16C1025 I1 FR 16C1025I1
Authority
FR
France
Prior art keywords
amino
cyanoethenyl
dimethylphenyl
pyrimidinyl
benzonitrile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR16C1025C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38091637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR16C1025(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from MYPI20043578A external-priority patent/MY169670A/en
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of FR16C1025I1 publication Critical patent/FR16C1025I1/en
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Abstract

The present invention relates to a pharmaceutical composition comprising as active ingredient the hydrochloric acid salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile and to processes for their preparation.
FR16C1025C 2004-09-02 2016-12-20 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile salt Active FR16C1025I1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
MYPI20043578A MY169670A (en) 2003-09-03 2004-09-02 Combinations of a pyrimidine containing nnrti with rt inhibitors
PCT/EP2004/052028 WO2005021001A1 (en) 2003-09-03 2004-09-03 Combinations of a pyrimidine containing nnrti with rt inhibitors
EP05101467 2005-02-25

Publications (1)

Publication Number Publication Date
FR16C1025I1 true FR16C1025I1 (en) 2017-02-03

Family

ID=38091637

Family Applications (2)

Application Number Title Priority Date Filing Date
FR16C1025C Active FR16C1025I1 (en) 2004-09-02 2016-12-20 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile salt
FR16C1023C Active FR16C1023I1 (en) 2004-09-02 2016-12-20 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile salt

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR16C1023C Active FR16C1023I1 (en) 2004-09-02 2016-12-20 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile salt

Country Status (21)

Country Link
EP (1) EP1632232B3 (en)
JP (1) JP4912309B2 (en)
CN (1) CN104586850A (en)
AT (1) ATE508748T1 (en)
BR (1) BRPI0514871A (en)
CY (3) CY1112249T1 (en)
DK (1) DK1632232T6 (en)
EA (1) EA013686B1 (en)
ES (1) ES2371442T7 (en)
FR (2) FR16C1025I1 (en)
HK (1) HK1210029A1 (en)
HU (2) HUS1600060I1 (en)
IL (1) IL181650A (en)
LT (2) LTPA2016043I1 (en)
ME (1) ME01246B (en)
MX (1) MX2007002595A (en)
NI (1) NI200700068A (en)
NO (3) NO340654B1 (en)
PT (1) PT1632232E (en)
RS (1) RS51923B2 (en)
SI (1) SI1632232T1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
NZ569347A (en) 2006-01-20 2011-07-29 Tibotec Pharm Ltd Long term treatment of HIV-infection with 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
TWI494133B (en) 2007-03-14 2015-08-01 Tibotec Pharm Ltd Powders for reconstitution
PE20211657A1 (en) 2010-11-19 2021-08-24 Gilead Sciences Inc THERAPEUTIC COMPOSITIONS INCLUDING RILPIVIRIN HCL AND TENOFOVIR DISOPROXIL FUMARATE
BR112013016546A2 (en) * 2011-04-15 2016-09-27 Emcure Pharmaceuticals Ltd process for rilpivirine improvement
EP2604593A1 (en) 2011-12-14 2013-06-19 Sandoz AG Polymorph of Rilpivirine hydrochloride and its use as antiviral
WO2013087794A1 (en) 2011-12-14 2013-06-20 Sandoz Ag Polymorph of rilpivirine hydrochloride and its use as antiviral
EP2628732A1 (en) * 2012-02-20 2013-08-21 Sandoz AG Novel crystalline form of rilpivirine hydrochloride
WO2013153162A1 (en) * 2012-04-11 2013-10-17 Sandoz Ag Polymorph of rilpivirine hydrochloride
WO2013153161A2 (en) * 2012-04-11 2013-10-17 Sandoz Ag Novel polymorph of rilpivirine hydrochloride
CN103570688B (en) * 2012-07-19 2016-06-08 中国科学院上海药物研究所 2,5-diaminomethyl pyrazine compounds, its pharmaceutical composition, preparation method and purposes
GR1008965B (en) * 2015-12-02 2017-02-28 Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων Pharmaceutical darunavir-containing formulation - preparation method thereof
RU2616267C1 (en) * 2016-01-25 2017-04-13 Закрытое Акционерное Общество "БИОКОМ" Solid drug form of indinavir with immediate release and method of obtaining thereof
HRP20240118T1 (en) * 2016-10-24 2024-04-12 Janssen Sciences Ireland Unlimited Company Dispersible compositions
CN114392241B (en) * 2022-01-10 2023-07-25 安徽贝克生物制药有限公司 Ripide Wei Linpian and preparation method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307543B1 (en) * 1998-09-10 2001-10-23 Silicon Image, Inc. Bi-directional data transfer using two pair of differential lines as a single additional differential pair
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
JO3429B1 (en) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv Hiv inhibiting pyrimidines derivatives
NZ538611A (en) * 2002-08-09 2007-03-30 Janssen Pharmaceutica Nv Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
WO2004050068A1 (en) * 2002-11-29 2004-06-17 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
CL2004000192A1 (en) * 2003-02-07 2005-03-18 Janssen Pharmaceutica Nv USE OF COMPOUNDS DERIVED FROM 2-AMINOPIRIMIDINE TO PREPARE A MEDICINAL PRODUCT FOR THE PREVENTION OF HIV INFECTION SEXUAL RELATIONS OR AN INTIMATE COUPLE CONTACT.

Also Published As

Publication number Publication date
MX2007002595A (en) 2007-04-25
IL181650A (en) 2012-08-30
FR16C1023I1 (en) 2017-02-03
EP1632232B1 (en) 2011-05-11
ME01246B (en) 2013-06-20
NO340654B1 (en) 2017-05-22
EP1632232B3 (en) 2022-03-30
CY2016050I1 (en) 2017-07-12
HUS1600061I1 (en) 2017-01-30
RS51923B (en) 2012-02-29
ATE508748T1 (en) 2011-05-15
EA200700536A1 (en) 2007-08-31
CY2016051I1 (en) 2017-07-12
HUS1600060I1 (en) 2017-01-30
BRPI0514871A (en) 2008-06-24
IL181650A0 (en) 2007-07-04
SI1632232T1 (en) 2011-09-30
LTPA2016042I1 (en) 2017-01-10
EP1632232A1 (en) 2006-03-08
NI200700068A (en) 2016-09-29
NO2017063I1 (en) 2017-11-21
NO20071745L (en) 2007-04-02
ES2371442T3 (en) 2012-01-02
CN104586850A (en) 2015-05-06
JP4912309B2 (en) 2012-04-11
DK1632232T6 (en) 2022-04-19
EA013686B1 (en) 2010-06-30
RS51923B2 (en) 2022-05-31
JP2008511592A (en) 2008-04-17
CY1112249T1 (en) 2015-12-09
HK1210029A1 (en) 2016-04-15
ES2371442T7 (en) 2022-05-12
LTPA2016043I1 (en) 2017-01-10
PT1632232E (en) 2011-08-02
NO2017065I1 (en) 2017-11-21
DK1632232T3 (en) 2011-08-22

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