FR16C0028I1 - VIRAL VECTORS AND THEIR USE IN THERAPEUTIC METHODS - Google Patents
VIRAL VECTORS AND THEIR USE IN THERAPEUTIC METHODSInfo
- Publication number
- FR16C0028I1 FR16C0028I1 FR16C0028C FR16C0028I1 FR 16C0028 I1 FR16C0028 I1 FR 16C0028I1 FR 16C0028 C FR16C0028 C FR 16C0028C FR 16C0028 I1 FR16C0028 I1 FR 16C0028I1
- Authority
- FR
- France
- Prior art keywords
- viral vectors
- therapeutic methods
- vectors
- methods
- treat disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/763—Herpes virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16661—Methods of inactivation or attenuation
- C12N2710/16662—Methods of inactivation or attenuation by genetic engineering
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16671—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27906901P | 2001-03-27 | 2001-03-27 | |
PCT/US2002/009512 WO2002076216A1 (en) | 2001-03-27 | 2002-03-27 | Viral vectors and their use in therapeutic methods |
Publications (2)
Publication Number | Publication Date |
---|---|
FR16C0028I1 true FR16C0028I1 (en) | 2016-07-22 |
FR16C0028I2 FR16C0028I2 (en) | 2018-05-11 |
Family
ID=23067509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR16C0028C Active FR16C0028I2 (en) | 2001-03-27 | 2016-06-15 | VIRAL VECTORS AND THEIR USE IN THERAPEUTIC METHODS |
Country Status (9)
Country | Link |
---|---|
US (6) | US7749745B2 (en) |
EP (1) | EP1381280B1 (en) |
JP (2) | JP4212897B2 (en) |
AT (1) | ATE508635T1 (en) |
AU (1) | AU2002306919B2 (en) |
CA (1) | CA2441663C (en) |
ES (1) | ES2366608T3 (en) |
FR (1) | FR16C0028I2 (en) |
WO (1) | WO2002076216A1 (en) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6379674B1 (en) * | 1997-08-12 | 2002-04-30 | Georgetown University | Use of herpes vectors for tumor therapy |
AU2002306919B2 (en) * | 2001-03-27 | 2007-11-22 | Tomoki Todo | Viral vectors and their use in therapeutic methods |
JP2005519091A (en) * | 2002-03-01 | 2005-06-30 | スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ | Prevention of cancer recurrence and metastasis |
ES2463442T3 (en) | 2004-03-31 | 2014-05-28 | Tomoki Todo | Enhancer of anti-cancer activity in viral therapy and method of prevention or treatment of cancer |
AU2005235826A1 (en) * | 2004-03-31 | 2005-11-03 | Tomoki Todo | Method of constructing recombinant herpes simplex virus |
US7731952B2 (en) * | 2004-06-24 | 2010-06-08 | New York University | Avirulent oncolytic herpes simplex virus strains engineered to counter the innate host response |
WO2009148488A2 (en) * | 2008-05-29 | 2009-12-10 | The General Hospital Corporation | Use of oncolytic herpes viruses for killing cancer stem cells |
US9267151B2 (en) * | 2008-08-20 | 2016-02-23 | Brainco Biopharma, S.L. | STXBP1 overexpressing mouse and its uses in screening of treatments for neuropsychiatric illness |
WO2011101912A1 (en) | 2010-02-19 | 2011-08-25 | 国立大学法人東京大学 | Recombinant herpes virus and pharmaceutical composition containing recombinant herpes virus |
EP2550362B1 (en) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
PL2753355T3 (en) | 2011-09-08 | 2019-04-30 | Benevir Biopharm Inc | Oncolytic herpes simplex virus and therapeutic uses thereof |
ES2781852T3 (en) | 2013-10-28 | 2020-09-08 | Univ Pittsburgh Commonwealth Sys Higher Education | Oncolytic HSV vector |
MA39818A (en) | 2014-03-30 | 2017-02-08 | Benevir Biopharm Inc | Exogenous tap inhibitor "armed" oncolytic viruses and therapeutic uses thereof |
WO2016100364A1 (en) | 2014-12-18 | 2016-06-23 | Amgen Inc. | Stable frozen herpes simplex virus formulation |
EP3307330B1 (en) | 2015-06-15 | 2021-03-10 | New York University | Method of treatment using oncolytic viruses |
EP3778881A1 (en) | 2016-01-08 | 2021-02-17 | Replimune Limited | Modified oncolytic virus |
RU2021114137A (en) | 2016-01-27 | 2021-05-25 | Онкорус, Инк. | ONCOLYTIC VIRAL VECTORS AND THEIR APPLICATION |
WO2017223146A1 (en) | 2016-06-22 | 2017-12-28 | Aeras | Recombinant cytomegalovirus vectors as vaccines for tuberculosis |
RU2021127872A (en) | 2016-06-30 | 2021-11-09 | Онкорус, Инк. | DELIVERY OF THERAPEUTIC POLYPEPTIDES THROUGH PSEUDOTYPED ONCOLYTIC VIRUSES |
WO2018170133A1 (en) | 2017-03-15 | 2018-09-20 | Amgen Inc. | Use of oncolytic viruses, alone or in combination with a checkpoint inhibitor, for the treatment of cancer |
CN106974942A (en) * | 2017-05-03 | 2017-07-25 | 武汉滨会生物科技股份有限公司 | Application of the recombination oncolytic II herpes simplex virus types in anti-lymphadenoma, cancer of the esophagus, breast cancer, pancreatic cancer drug is prepared |
JP7249323B2 (en) | 2017-07-26 | 2023-03-30 | オンコラス, インコーポレイテッド | Oncolytic virus vector and use thereof |
UY37829A (en) | 2017-08-03 | 2019-01-31 | Amgen Inc | INTERLEUCINE MUTEINS 21 AND TREATMENT METHODS |
MA49849A (en) | 2017-08-07 | 2020-06-17 | Amgen Inc | TREATMENT OF NEGATIVE TRIPLE BREAST CANCER OR COLORECTAL CANCER CONTAINING HEPATIC METASTASIS WITH ANTI-PD-L1 ANTIBODY AND ONCOLYTIC VIRUS |
IL293443A (en) | 2017-09-08 | 2022-07-01 | Amgen Inc | Inhibitors of kras g12c and methods of using the same |
EP3697806A4 (en) | 2017-10-17 | 2021-10-27 | International AIDS Vaccine Initiative, Inc. | Tuberculosis antigen cassettes |
WO2019133847A1 (en) | 2017-12-29 | 2019-07-04 | Oncorus, Inc. | Oncolytic viral delivery of therapeutic polypeptides |
PE20211270A1 (en) | 2018-01-12 | 2021-07-19 | Amgen Inc | ANTI-PD-1 ANTIBODIES AND TREATMENT METHODS |
CA3095427A1 (en) | 2018-03-30 | 2019-10-03 | Tomoki Todo | Swelling-suppressive oncolytic virus |
EP3653716A1 (en) * | 2018-11-19 | 2020-05-20 | HSF Pharmaceuticals | Replication-competent controlled alpha-herpesvirus virus vectors and uses therefore |
JP2022516077A (en) | 2018-12-27 | 2022-02-24 | アムジェン インコーポレイテッド | Freeze-dried virus preparation |
KR20210135532A (en) | 2019-03-05 | 2021-11-15 | 암젠 인크 | Use of oncolytic viruses for the treatment of cancer |
TW202102543A (en) | 2019-03-29 | 2021-01-16 | 美商安進公司 | Use of oncolytic viruses in the neoadjuvant therapy of cancer |
US20230147832A1 (en) * | 2020-01-22 | 2023-05-11 | City Of Hope | Oncolytic virus compositions including il-15 complex and methods for the treatment of cancer |
WO2024038857A1 (en) * | 2022-08-16 | 2024-02-22 | 具紀 藤堂 | Pharmaceutical composition containing herpes simplex virus vector |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2659628B1 (en) * | 1990-03-16 | 1992-09-18 | Marin S Communication | BOX OR CASE DEVICE WITH MOBILE COVER. |
CA2039921A1 (en) | 1990-04-16 | 1991-10-17 | Xandra O. Breakefield | Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication |
GB9102126D0 (en) | 1991-01-31 | 1991-03-13 | Smithkline Beecham Biolog | Novel vaccine |
US5750398A (en) | 1993-11-30 | 1998-05-12 | David C. Johnson | Vector, element and method for inhibiting immune recognition |
US5728379A (en) | 1994-06-23 | 1998-03-17 | Georgetown University | Tumor- or cell-specific herpes simplex virus replication |
US5585096A (en) | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
GB9415320D0 (en) | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
US6261552B1 (en) * | 1997-05-22 | 2001-07-17 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus vectors |
US5824318A (en) | 1996-07-24 | 1998-10-20 | American Cyanamid Company | Avirulent herpetic viruses useful as tumoricidal agents and vaccines |
GB9615794D0 (en) * | 1996-07-26 | 1996-09-04 | Medical Res Council | Mutant herpes simplex virus strains and uses thereof |
US6379674B1 (en) | 1997-08-12 | 2002-04-30 | Georgetown University | Use of herpes vectors for tumor therapy |
KR100802403B1 (en) | 2000-01-21 | 2008-02-13 | 바이오벡스 리미티드 | Virus Strains |
AU6814601A (en) * | 2000-06-01 | 2001-12-11 | Sloan Kettering Inst Cancer | Use of mutant herpes viruses and anticancer agents in the treatment of cancer |
AU2002306919B2 (en) * | 2001-03-27 | 2007-11-22 | Tomoki Todo | Viral vectors and their use in therapeutic methods |
-
2002
- 2002-03-27 AU AU2002306919A patent/AU2002306919B2/en not_active Expired
- 2002-03-27 CA CA2441663A patent/CA2441663C/en not_active Expired - Lifetime
- 2002-03-27 US US10/107,036 patent/US7749745B2/en active Active
- 2002-03-27 WO PCT/US2002/009512 patent/WO2002076216A1/en active Application Filing
- 2002-03-27 EP EP02753865A patent/EP1381280B1/en not_active Expired - Lifetime
- 2002-03-27 ES ES02753865T patent/ES2366608T3/en not_active Expired - Lifetime
- 2002-03-27 JP JP2002574742A patent/JP4212897B2/en not_active Expired - Lifetime
- 2002-03-27 AT AT02753865T patent/ATE508635T1/en not_active IP Right Cessation
-
2008
- 2008-09-22 JP JP2008242828A patent/JP2009060907A/en active Pending
-
2010
- 2010-03-11 US US12/721,599 patent/US8470577B2/en not_active Expired - Lifetime
-
2013
- 2013-06-24 US US13/924,936 patent/US8871193B2/en not_active Expired - Lifetime
-
2014
- 2014-10-27 US US14/524,163 patent/US9555072B2/en not_active Expired - Lifetime
-
2016
- 2016-06-15 FR FR16C0028C patent/FR16C0028I2/en active Active
- 2016-12-19 US US15/383,578 patent/US10532095B2/en not_active Expired - Fee Related
-
2020
- 2020-01-10 US US16/739,890 patent/US20200345835A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1381280A4 (en) | 2006-06-14 |
JP4212897B2 (en) | 2009-01-21 |
WO2002076216A1 (en) | 2002-10-03 |
US20200345835A1 (en) | 2020-11-05 |
US20110070262A1 (en) | 2011-03-24 |
AU2002306919B2 (en) | 2007-11-22 |
ATE508635T1 (en) | 2011-05-15 |
US20150071965A1 (en) | 2015-03-12 |
ES2366608T3 (en) | 2011-10-21 |
CA2441663C (en) | 2013-01-22 |
US10532095B2 (en) | 2020-01-14 |
EP1381280A1 (en) | 2004-01-21 |
US8470577B2 (en) | 2013-06-25 |
US9555072B2 (en) | 2017-01-31 |
JP2009060907A (en) | 2009-03-26 |
US20130280299A1 (en) | 2013-10-24 |
US8871193B2 (en) | 2014-10-28 |
US20020187163A1 (en) | 2002-12-12 |
US20170290908A1 (en) | 2017-10-12 |
EP1381280B1 (en) | 2011-05-11 |
FR16C0028I2 (en) | 2018-05-11 |
US7749745B2 (en) | 2010-07-06 |
JP2004528836A (en) | 2004-09-24 |
CA2441663A1 (en) | 2002-10-03 |
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