FR1604469A - Antirheumatic, diuretic, sedative n-substitu- - ted amides - Google Patents

Antirheumatic, diuretic, sedative n-substitu- - ted amides

Info

Publication number
FR1604469A
FR1604469A FR182827A FR182827A FR1604469A FR 1604469 A FR1604469 A FR 1604469A FR 182827 A FR182827 A FR 182827A FR 182827 A FR182827 A FR 182827A FR 1604469 A FR1604469 A FR 1604469A
Authority
FR
France
Prior art keywords
orally
antirheumatic
diuretic
sedative
substitu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR182827A
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to FR182827A priority Critical patent/FR1604469A/en
Priority to FR183302A priority patent/FR8287M/fr
Application granted granted Critical
Publication of FR1604469A publication Critical patent/FR1604469A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Pharmaceutical compositions containing as active ingredient a compound of formula Y.NH.CO.Ar where Y is benzhydryl, fluoren-9-yl-dibenzon 2,3;6,7 cycloheptadien-5-yl, xanthen-9-yl; Ar = aryl e.g. phenyl, naphthyl or heterocyclic e.g. pyridyl. The compounds are antirheumatic, antiinflammatory, analgesic, diuretic and sedative agents; 40-70% inhibition of mouse writhing at 50-200 mg/kg. orally, 40% reduction in the carrageenan-induced inflammation of the rat foot by 200 mg/kg. orally of N-(xanthen-9-yl) isonicotinamide; 10 mg/kg. orally of the same compound in the rat gives a 50% incease in urine output without significant loss of potassium. Very low toxicity; no deaths after 2000 mg/kg. orally in mice.
FR182827A 1968-12-31 1968-12-31 Antirheumatic, diuretic, sedative n-substitu- - ted amides Expired FR1604469A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR182827A FR1604469A (en) 1968-12-31 1968-12-31 Antirheumatic, diuretic, sedative n-substitu- - ted amides
FR183302A FR8287M (en) 1968-12-31 1969-03-28

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR182827A FR1604469A (en) 1968-12-31 1968-12-31 Antirheumatic, diuretic, sedative n-substitu- - ted amides

Publications (1)

Publication Number Publication Date
FR1604469A true FR1604469A (en) 1971-11-08

Family

ID=8659782

Family Applications (1)

Application Number Title Priority Date Filing Date
FR182827A Expired FR1604469A (en) 1968-12-31 1968-12-31 Antirheumatic, diuretic, sedative n-substitu- - ted amides

Country Status (1)

Country Link
FR (1) FR1604469A (en)

Similar Documents

Publication Publication Date Title
ATE190838T1 (en) INJECTABLE MEDICINAL PREPARATIONS CONTAINING TAXAN DERIVATIVES
DE3480474D1 (en) 2-AMINO-5-HYDROXY-4-METHYLPYRIMIDINE DERIVATIVES
IE45256L (en) Quinazolone derivatives
BE756970A (en) IMPROVEMENTS FOR INCINERATORS, ESPECIALLY OF GARBAGE
HUP9901630A2 (en) Novel indole-2,3-dione-3-oxime derivatives
ES446222A1 (en) Antiparasitic salicylanilide derivatives
FR1604469A (en) Antirheumatic, diuretic, sedative n-substitu- - ted amides
ES431497A1 (en) S-triazolo(1,5-a)pyridine derivative
GB1259415A (en)
GB1264798A (en)
ES481855A1 (en) 6-Methoxy-2-acethylnaphthalene oximes
GB1280418A (en) Sulfonamides
GB1314899A (en) Thiosemicarbazones processes for their preparations and compositions incorporating them
JPS525769A (en) Preparation of 3-substituted pyrolidine derivatives
GB1116775A (en) ªß-hydroxy-acrylic acid derivatives and process for their manufacture
JPS5278887A (en) Synthesis of n-(2-tetrahydrofuryl)-5-fluorouracil
FR2016718A1 (en) Anti inflammatory 2 methyl 3 (2 (2diethylaminoethoxy) - phenyl) quinazolin 4 one
GB1133080A (en) Improvements in or relating to derivatives of nitrofuran
ES471207A1 (en) Pyrimidino (1,2a)heterocyclic amide derivatives
GB1285550A (en) Benzodiazepine derivatives
JPS5259182A (en) Preparation of cephalosporin compounds
IE36204B1 (en) Penicilloic acid derivatives
ES362712A1 (en) Improvements in or relating to benzylideneamino guanidine derivatives
JPS5283372A (en) Synthesis of imidazole derivatives
FI49305C (en) Process for the preparation of pharmacologically active 2-substituted isoxazolidine derivatives.

Legal Events

Date Code Title Description
ST Notification of lapse