FR1303080A - Disubstituted piperazines - Google Patents

Disubstituted piperazines

Info

Publication number
FR1303080A
FR1303080A FR868980A FR868980A FR1303080A FR 1303080 A FR1303080 A FR 1303080A FR 868980 A FR868980 A FR 868980A FR 868980 A FR868980 A FR 868980A FR 1303080 A FR1303080 A FR 1303080A
Authority
FR
France
Prior art keywords
disubstituted piperazines
piperazines
disubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR868980A
Other languages
French (fr)
Inventor
Gilbert Regnier
Roger Canevari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Priority to FR868980A priority Critical patent/FR1303080A/en
Priority to FR876804A priority patent/FR1549M/en
Application granted granted Critical
Publication of FR1303080A publication Critical patent/FR1303080A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/30—Nitrogen atoms non-acylated
FR868980A 1961-07-25 1961-07-25 Disubstituted piperazines Expired FR1303080A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR868980A FR1303080A (en) 1961-07-25 1961-07-25 Disubstituted piperazines
FR876804A FR1549M (en) 1961-07-25 1961-10-24 New vasodilator drug based on disubstituted piperazine.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR868980A FR1303080A (en) 1961-07-25 1961-07-25 Disubstituted piperazines

Publications (1)

Publication Number Publication Date
FR1303080A true FR1303080A (en) 1962-09-07

Family

ID=8760035

Family Applications (2)

Application Number Title Priority Date Filing Date
FR868980A Expired FR1303080A (en) 1961-07-25 1961-07-25 Disubstituted piperazines
FR876804A Active FR1549M (en) 1961-07-25 1961-10-24 New vasodilator drug based on disubstituted piperazine.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR876804A Active FR1549M (en) 1961-07-25 1961-10-24 New vasodilator drug based on disubstituted piperazine.

Country Status (1)

Country Link
FR (2) FR1303080A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187639A1 (en) * 1985-01-11 1986-07-16 Kanebo, Ltd. Novel piperazine derivatives, processes for production thereof, and pharmaceutical compositions comprising said compounds as active ingredient
US4663325A (en) * 1984-03-30 1987-05-05 Kanebo Ltd. 1-(2,3,4-tri-methoxybenzyl)-4[bis(4-fluorophenyl)methyl] piperazines are useful for treating cerebrovascular disease
EP0847999A1 (en) * 1996-12-16 1998-06-17 Adir Et Compagnie N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them
WO1998037077A1 (en) * 1997-02-24 1998-08-27 Zymogenetics, Inc. Calcitonin mimetics
WO1999042107A1 (en) * 1998-02-23 1999-08-26 Zymogenetics, Inc. Piperazine derivatives for treating bone deficit conditions
CN103554057A (en) * 2013-11-13 2014-02-05 武汉武药科技有限公司 Trimetazidine derivative and preparation method thereof
CN109734683A (en) * 2018-12-14 2019-05-10 北京嘉林药业股份有限公司 The method that Trimetazidine production waste is converted to utility

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663325A (en) * 1984-03-30 1987-05-05 Kanebo Ltd. 1-(2,3,4-tri-methoxybenzyl)-4[bis(4-fluorophenyl)methyl] piperazines are useful for treating cerebrovascular disease
EP0187639A1 (en) * 1985-01-11 1986-07-16 Kanebo, Ltd. Novel piperazine derivatives, processes for production thereof, and pharmaceutical compositions comprising said compounds as active ingredient
EP0847999A1 (en) * 1996-12-16 1998-06-17 Adir Et Compagnie N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them
FR2757164A1 (en) * 1996-12-16 1998-06-19 Adir NOVEL N-BENZYLPIPERAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
US6124299A (en) * 1997-02-24 2000-09-26 Zymogenetics, Inc. Calcitonin mimetics
WO1998037077A1 (en) * 1997-02-24 1998-08-27 Zymogenetics, Inc. Calcitonin mimetics
US6395740B1 (en) 1997-02-24 2002-05-28 Zymogenetics, Inc. Calcitonin mimetics
WO1999042107A1 (en) * 1998-02-23 1999-08-26 Zymogenetics, Inc. Piperazine derivatives for treating bone deficit conditions
US6268367B1 (en) 1998-02-23 2001-07-31 Zymogenetics, Inc. Piperazine derivatives for treating bone deficit conditions
CN103554057A (en) * 2013-11-13 2014-02-05 武汉武药科技有限公司 Trimetazidine derivative and preparation method thereof
CN103554057B (en) * 2013-11-13 2016-04-20 武汉武药科技有限公司 Trimetazidine derivative and preparation method thereof
CN109734683A (en) * 2018-12-14 2019-05-10 北京嘉林药业股份有限公司 The method that Trimetazidine production waste is converted to utility
CN109734683B (en) * 2018-12-14 2020-12-18 北京嘉林药业股份有限公司 Method for converting trimetazidine production waste into useful substances

Also Published As

Publication number Publication date
FR1549M (en) 1962-10-29

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