FI970565A0 - HIV proteasinhibitorkombination - Google Patents
HIV proteasinhibitorkombinationInfo
- Publication number
- FI970565A0 FI970565A0 FI970565A FI970565A FI970565A0 FI 970565 A0 FI970565 A0 FI 970565A0 FI 970565 A FI970565 A FI 970565A FI 970565 A FI970565 A FI 970565A FI 970565 A0 FI970565 A0 FI 970565A0
- Authority
- FI
- Finland
- Prior art keywords
- hiv
- hiv protease
- proteasinhibitorkombination
- treatment
- methods
- Prior art date
Links
- 208000030507 AIDS Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000004030 hiv protease inhibitor Substances 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108010010369 HIV Protease Proteins 0.000 abstract 1
- 229940122440 HIV protease inhibitor Drugs 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 229940042443 other antivirals in atc Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The combination of the HIV protease inhibitor Compound J and any one or more of four other potent HIV protease inhibitors is useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28947494A | 1994-08-11 | 1994-08-11 | |
| US33936994A | 1994-11-14 | 1994-11-14 | |
| US49246195A | 1995-07-20 | 1995-07-20 | |
| PCT/US1995/009956 WO1996004913A1 (en) | 1994-08-11 | 1995-08-07 | Hiv protease inhibitor combination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI970565A0 true FI970565A0 (en) | 1997-02-10 |
| FI970565A FI970565A (en) | 1997-02-10 |
Family
ID=27403895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI970565A FI970565A (en) | 1994-08-11 | 1997-02-10 | HIV protease inhibitory combination |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0774969B8 (en) |
| JP (1) | JPH10504036A (en) |
| KR (1) | KR970704441A (en) |
| CN (1) | CN1101190C (en) |
| AT (1) | ATE232727T1 (en) |
| AU (1) | AU698664B2 (en) |
| CA (1) | CA2197207C (en) |
| CY (1) | CY2360B1 (en) |
| CZ (1) | CZ292577B6 (en) |
| DE (1) | DE69529678T2 (en) |
| DK (1) | DK0774969T3 (en) |
| ES (1) | ES2190456T3 (en) |
| FI (1) | FI970565A (en) |
| HU (1) | HUT76540A (en) |
| IL (1) | IL114808A (en) |
| MX (1) | MX9701121A (en) |
| NO (1) | NO314168B1 (en) |
| PL (1) | PL181578B1 (en) |
| SK (1) | SK18197A3 (en) |
| WO (1) | WO1996004913A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA49803C2 (en) * | 1994-06-03 | 2002-10-15 | Дж.Д. Сьорль Енд Ко | Method for treatment of retrovirus infections |
| US6037157A (en) * | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
| WO1998020888A1 (en) * | 1996-11-08 | 1998-05-22 | Japan Energy Corporation | Aids remedy |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US517041A (en) * | 1894-03-27 | Fruit-picker | ||
| CA1340588C (en) * | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| DE69124110T2 (en) * | 1990-11-19 | 1997-06-05 | Monsanto Co | RETROVIRAL PROTEASE INHIBITORS |
| ES2059289T3 (en) * | 1990-11-19 | 1997-10-16 | Monsanto Co | RETROVIRAL PROTEASE INHIBITORS. |
| IE913840A1 (en) * | 1990-11-20 | 1992-05-20 | Abbott Lab | Retroviral protease inhibiting compounds |
| DK0541168T3 (en) * | 1991-11-08 | 1998-05-11 | Merck & Co Inc | HIV protease inhibitors suitable for the treatment of AIDS |
| KR100333016B1 (en) * | 1992-12-29 | 2002-11-22 | 아보트 러보러터리즈 | Retroviral protease inhibitory compounds, methods for their preparation and pharmaceutical compositions containing them |
-
1995
- 1995-08-02 IL IL11480895A patent/IL114808A/en not_active IP Right Cessation
- 1995-08-07 WO PCT/US1995/009956 patent/WO1996004913A1/en active IP Right Grant
- 1995-08-07 JP JP8507422A patent/JPH10504036A/en active Pending
- 1995-08-07 DK DK95930118T patent/DK0774969T3/en active
- 1995-08-07 KR KR1019970700855A patent/KR970704441A/en not_active Application Discontinuation
- 1995-08-07 SK SK181-97A patent/SK18197A3/en unknown
- 1995-08-07 AT AT95930118T patent/ATE232727T1/en not_active IP Right Cessation
- 1995-08-07 AU AU33611/95A patent/AU698664B2/en not_active Ceased
- 1995-08-07 CN CN95195548A patent/CN1101190C/en not_active Expired - Fee Related
- 1995-08-07 CA CA002197207A patent/CA2197207C/en not_active Expired - Fee Related
- 1995-08-07 EP EP95930118A patent/EP0774969B8/en not_active Expired - Lifetime
- 1995-08-07 CZ CZ1997389A patent/CZ292577B6/en not_active IP Right Cessation
- 1995-08-07 MX MX9701121A patent/MX9701121A/en unknown
- 1995-08-07 ES ES95930118T patent/ES2190456T3/en not_active Expired - Lifetime
- 1995-08-07 PL PL95318506A patent/PL181578B1/en not_active IP Right Cessation
- 1995-08-07 HU HU9700402A patent/HUT76540A/en unknown
- 1995-08-07 DE DE69529678T patent/DE69529678T2/en not_active Expired - Fee Related
-
1997
- 1997-02-10 FI FI970565A patent/FI970565A/en not_active Application Discontinuation
- 1997-02-11 NO NO19970632A patent/NO314168B1/en unknown
-
2003
- 2003-05-07 CY CY0300040A patent/CY2360B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69529678T2 (en) | 2003-09-25 |
| PL318506A1 (en) | 1997-06-23 |
| HUT76540A (en) | 1997-09-29 |
| CA2197207C (en) | 2006-10-17 |
| JPH10504036A (en) | 1998-04-14 |
| CY2360B1 (en) | 2004-06-04 |
| SK18197A3 (en) | 1997-09-10 |
| IL114808A0 (en) | 1995-12-08 |
| EP0774969B1 (en) | 2003-02-19 |
| KR970704441A (en) | 1997-09-06 |
| EP0774969A1 (en) | 1997-05-28 |
| DK0774969T3 (en) | 2003-03-31 |
| ATE232727T1 (en) | 2003-03-15 |
| EP0774969B8 (en) | 2003-07-02 |
| CZ38997A3 (en) | 1997-11-12 |
| NO970632D0 (en) | 1997-02-11 |
| MX9701121A (en) | 1997-05-31 |
| CN1160350A (en) | 1997-09-24 |
| IL114808A (en) | 1999-10-28 |
| NO314168B1 (en) | 2003-02-10 |
| CA2197207A1 (en) | 1996-02-22 |
| AU3361195A (en) | 1996-03-07 |
| AU698664B2 (en) | 1998-11-05 |
| DE69529678D1 (en) | 2003-03-27 |
| PL181578B1 (en) | 2001-08-31 |
| WO1996004913A1 (en) | 1996-02-22 |
| ES2190456T3 (en) | 2003-08-01 |
| FI970565A (en) | 1997-02-10 |
| CZ292577B6 (en) | 2003-10-15 |
| NO970632L (en) | 1997-04-10 |
| CN1101190C (en) | 2003-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |