FI954719A0 - Novel compounds having the structure 1- (arylalkenyl) -4- (arylmethyl) piperazine, process for their preparation and pharmaceutical compositions containing them - Google Patents

Novel compounds having the structure 1- (arylalkenyl) -4- (arylmethyl) piperazine, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
FI954719A0
FI954719A0 FI954719A FI954719A FI954719A0 FI 954719 A0 FI954719 A0 FI 954719A0 FI 954719 A FI954719 A FI 954719A FI 954719 A FI954719 A FI 954719A FI 954719 A0 FI954719 A0 FI 954719A0
Authority
FI
Finland
Prior art keywords
arylmethyl
arylalkenyl
piperazine
preparation
pharmaceutical compositions
Prior art date
Application number
FI954719A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI954719A (en
Inventor
Genevieve Baziard-Mouysset
Sallouma Younes
Youssef Labssita
Marc Payard
Daniel-Henri Caignard
Pierre Renard
Marie-Claire Rettori
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of FI954719A0 publication Critical patent/FI954719A0/en
Publication of FI954719A publication Critical patent/FI954719A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI954719A 1994-10-10 1995-10-04 New compounds having 1- (arylalkenyl) -4- (arylmethyl) -piperazine structure, process for their preparation, and pharmaceutical compositions containing these compounds FI954719A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412053A FR2725445B1 (en) 1994-10-10 1994-10-10 NOVEL DERIVATIVES WITH A 1-ARYLALKENYL 4-ARYL ALKYL PIPERAZINE STRUCTURE, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (2)

Publication Number Publication Date
FI954719A0 true FI954719A0 (en) 1995-10-04
FI954719A FI954719A (en) 1996-04-11

Family

ID=9467706

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954719A FI954719A (en) 1994-10-10 1995-10-04 New compounds having 1- (arylalkenyl) -4- (arylmethyl) -piperazine structure, process for their preparation, and pharmaceutical compositions containing these compounds

Country Status (10)

Country Link
EP (1) EP0707004A1 (en)
JP (1) JP3035475B2 (en)
CN (1) CN1053441C (en)
AU (1) AU692594B2 (en)
CA (1) CA2160214A1 (en)
FI (1) FI954719A (en)
FR (1) FR2725445B1 (en)
NO (1) NO305699B1 (en)
NZ (1) NZ280192A (en)
ZA (1) ZA958532B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751645B1 (en) * 1996-07-29 1998-12-24 Sanofi Sa AMINES FOR THE MANUFACTURE OF DRUGS TO PREVENT THE PROLIFERATION OF TUMOR CELLS
GB0224917D0 (en) * 2002-10-25 2002-12-04 Novartis Ag Organic compounds
SE0400440D0 (en) * 2004-02-25 2004-02-25 Active Biotech Ab Novel Cinnamic Amides
JP5436419B2 (en) * 2008-06-04 2014-03-05 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 Method for treating mental disorder and pharmaceutical composition for treatment
US20230364033A1 (en) 2020-09-17 2023-11-16 Meletios Therapeutics Compounds for treating virus infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6219577A (en) * 1985-07-16 1987-01-28 Kanebo Ltd Novel benzylpiperazine derivative and drug composition comprising same as active ingredient
EP0551617A3 (en) * 1991-12-13 1993-11-03 Ube Industries Cinnamyl piperazine derivatives method of manufacturing the same and agricultural/horticultural fungicides containing cinnamyl piperazine derivatives

Also Published As

Publication number Publication date
FR2725445B1 (en) 1996-10-31
ZA958532B (en) 1996-05-10
JPH08176129A (en) 1996-07-09
NO305699B1 (en) 1999-07-12
FR2725445A1 (en) 1996-04-12
AU692594B2 (en) 1998-06-11
NO954010D0 (en) 1995-10-09
CA2160214A1 (en) 1996-04-11
CN1133288A (en) 1996-10-16
EP0707004A1 (en) 1996-04-17
CN1053441C (en) 2000-06-14
AU3311495A (en) 1996-04-26
NO954010L (en) 1996-04-11
FI954719A (en) 1996-04-11
JP3035475B2 (en) 2000-04-24
NZ280192A (en) 1996-02-27

Similar Documents

Publication Publication Date Title
HUP9902471A3 (en) Piperazine and piperidine compounds, process for their preparation and pharmaceutical compositions containing the same
FI963566A0 (en) New piperazine derivatives, methods for their preparation and compositions containing them
AU1198699A (en) Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them
DE69622992D1 (en) SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
AU4055895A (en) Piperazine derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them
HUP0003844A3 (en) Novel spiroazabicyclic heterocyclic compounds, process for their preparation, their use and pharmaceutical compositions containing them
ATE234291T1 (en) METALPROTEINASE INHIBITORS, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE THEREOF AND METHOD FOR THE PRODUCTION THEREOF
FI972309A0 (en) 2-Heterocyclyloxy and thiomethyl-1,2,5-thiadizolidin-3-one 1,1-dioxides, compositions containing them and process for their preparation
EE9700020A (en) Heteroatom-containing cyclopentanepyridyloxazolidinones, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds
HUP9801692A3 (en) Benzimidazole compounds, pharmaceutical compositions containing them and their use for producing pharmaceutical compositions
HUP9600211A3 (en) Heterocyclic compounds, process for producing them and pharmaceutical compositions containing them, as an activ ingredient
EE03177B1 (en) Heterobicyclic compounds, methods for their preparation and pharmaceutical compositions containing said compounds
EE9700044A (en) Heteroaryloxazolidinones, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds.
EG24080A (en) New arylglycineamide derivatives, process for thw manufacture thereof and pharmaceutical compositions containing these compounds
HUP0002050A3 (en) Substituted imidazole compounds, process for producing them, pharmaceutical compositions containing them and their use
IL112443A0 (en) Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
NO972937D0 (en) Pharmaceutical piperazine compounds
GB2190677B (en) 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives, process for the preparation thereof and pharmaceutical compositions containing the same
FI960316A0 (en) Oxathiolanes, process for their preparation and pharmaceutical compositions containing them
EE200000129A (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ol, process for their preparation and use as pharmaceuticals
HUP9702341A3 (en) New imidazoline compounds, process for preparing them and pharmaceutical compositions containing them
FI956278A0 (en) Substituted 4-phenylthiazole derivatives, process for their preparation and pharmaceutical compositions containing them
AU5116590A (en) N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same
FI954719A0 (en) Novel compounds having the structure 1- (arylalkenyl) -4- (arylmethyl) piperazine, process for their preparation and pharmaceutical compositions containing them
FI953956A (en) 2,3-Ring-fused 1,4-dihydropyridines, processes for their preparation and their use as medicaments