FI944967A - Methods for preparing saccharin derivatives and their intermediates useful as proteolytic enzyme inhibitors - Google Patents

Methods for preparing saccharin derivatives and their intermediates useful as proteolytic enzyme inhibitors Download PDF

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Publication number
FI944967A
FI944967A FI944967A FI944967A FI944967A FI 944967 A FI944967 A FI 944967A FI 944967 A FI944967 A FI 944967A FI 944967 A FI944967 A FI 944967A FI 944967 A FI944967 A FI 944967A
Authority
FI
Finland
Prior art keywords
proteolytic enzyme
preparing
methods
enzyme inhibitors
intermediates useful
Prior art date
Application number
FI944967A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI103113B1 (en
FI944967A0 (en
FI103113B (en
Inventor
Richard Paul Dunlap
Neil Warren Boaz
Albert Joseph Mura
Dennis John Hlasta
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1990/002434 external-priority patent/WO1990013549A1/en
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of FI944967A0 publication Critical patent/FI944967A0/en
Publication of FI944967A publication Critical patent/FI944967A/en
Priority to FI960489A priority Critical patent/FI960489A/en
Application granted granted Critical
Publication of FI103113B1 publication Critical patent/FI103113B1/en
Publication of FI103113B publication Critical patent/FI103113B/en

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Abstract

The invention relates to a process for preparing saccharin derivatives which have the formula I and which can be used as inhibitors of a proteolytic enzyme, <IMAGE> where L is -O-, -S-, -SO- or -SO2-; (a) m = 0 and n = 0, (b) m = 1 and n = 1, or (c) m = 1 and n = 0; and R1, R2, R3 and R4 represent different substituents of organic compounds. The invention also relates to processes for preparing intermediates <IMAGE> which can be used when preparing the compounds (I).
FI944967A 1989-05-04 1994-10-21 Process for the preparation of saccharin derivatives useful as inhibitors of proteolytic enzyme FI103113B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI960489A FI960489A (en) 1989-05-04 1996-02-02 Process for the preparation of saccharin derivatives useful as inhibitors of proteolytic enzyme and intermediates thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34712689A 1989-05-04 1989-05-04
US34712589A 1989-05-04 1989-05-04
PCT/US1990/002434 WO1990013549A1 (en) 1989-05-04 1990-05-01 Saccharin derivatives useful as proteolytic enzyme inhibitors and preparation thereof
FI915093A FI103111B (en) 1989-05-04 1991-10-29 Process for the preparation of saccharin derivatives useful as inhibitors of proteolytic enzyme

Publications (4)

Publication Number Publication Date
FI944967A0 FI944967A0 (en) 1994-10-21
FI944967A true FI944967A (en) 1994-10-21
FI103113B1 FI103113B1 (en) 1999-04-30
FI103113B FI103113B (en) 1999-04-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
FI944967A FI103113B (en) 1989-05-04 1994-10-21 Process for the preparation of saccharin derivatives useful as inhibitors of proteolytic enzyme
FI960488A FI103114B1 (en) 1989-05-04 1996-02-02 Process for the preparation of saccharin derivatives useful as inhibitors of proteolytic enzyme

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI960488A FI103114B1 (en) 1989-05-04 1996-02-02 Process for the preparation of saccharin derivatives useful as inhibitors of proteolytic enzyme

Country Status (1)

Country Link
FI (2) FI103113B (en)

Also Published As

Publication number Publication date
FI103113B1 (en) 1999-04-30
FI944967A0 (en) 1994-10-21
FI103114B (en) 1999-04-30
FI960488A (en) 1996-02-02
FI103114B1 (en) 1999-04-30
FI960488A0 (en) 1996-02-02
FI103113B (en) 1999-04-30

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