FI943275A - TIE, a novel endothelial cell receptor tyrosine kinase - Google Patents

TIE, a novel endothelial cell receptor tyrosine kinase Download PDF

Info

Publication number
FI943275A
FI943275A FI943275A FI943275A FI943275A FI 943275 A FI943275 A FI 943275A FI 943275 A FI943275 A FI 943275A FI 943275 A FI943275 A FI 943275A FI 943275 A FI943275 A FI 943275A
Authority
FI
Finland
Prior art keywords
tie
tyrosine kinase
endothelial cell
cell receptor
receptor tyrosine
Prior art date
Application number
FI943275A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI943275A0 (en
Inventor
Juha Partanen
Elina Armstrong
Tomi P Maekelae
Jaana Korhonen
Kari Alitalo
Original Assignee
Helsinki University Holding Lt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinki University Holding Lt filed Critical Helsinki University Holding Lt
Priority to FI943275A priority Critical patent/FI943275A/en
Publication of FI943275A0 publication Critical patent/FI943275A0/en
Publication of FI943275A publication Critical patent/FI943275A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FI943275A 1992-01-09 1994-07-08 TIE, a novel endothelial cell receptor tyrosine kinase FI943275A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI943275A FI943275A (en) 1992-01-09 1994-07-08 TIE, a novel endothelial cell receptor tyrosine kinase

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81780092A 1992-01-09 1992-01-09
PCT/FI1993/000006 WO1993014124A1 (en) 1992-01-09 1993-01-08 Tie, a novel endothelial cell receptor tyrosine kinase
FI943275A FI943275A (en) 1992-01-09 1994-07-08 TIE, a novel endothelial cell receptor tyrosine kinase

Publications (2)

Publication Number Publication Date
FI943275A0 FI943275A0 (en) 1994-07-08
FI943275A true FI943275A (en) 1994-07-11

Family

ID=25223909

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943275A FI943275A (en) 1992-01-09 1994-07-08 TIE, a novel endothelial cell receptor tyrosine kinase

Country Status (8)

Country Link
EP (1) EP0620826A1 (en)
JP (1) JPH07506242A (en)
KR (1) KR940703857A (en)
AU (1) AU3353293A (en)
CA (1) CA2127540A1 (en)
FI (1) FI943275A (en)
HU (1) HUT69792A (en)
WO (1) WO1993014124A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955291A (en) * 1992-01-09 1999-09-21 Alitalo; Kari Antibodies recognizing tie receptor tyrosine kinase and uses thereof
US5776755A (en) * 1992-10-09 1998-07-07 Helsinki University Licensing, Ltd. FLT4, a receptor tyrosine kinase
US6107046A (en) * 1992-10-09 2000-08-22 Orion Corporation Antibodies to Flt4, a receptor tyrosine kinase and uses thereof
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
WO1994010197A1 (en) * 1992-10-30 1994-05-11 Ludwig Institute For Cancer Research A novel protein tyrosine kinase
AU697142B2 (en) * 1993-11-23 1998-10-01 Genentech Inc. Protein tyrosine kinases named Rse
US6001621A (en) * 1993-11-23 1999-12-14 Genetech, Inc. Protein tyrosine kinases
US5536641A (en) * 1994-05-17 1996-07-16 Memorial Sloane Kittering Cancer Center Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1 and uses thereof for detection of, and isolation of, vascular endothelial cells
US5585269A (en) * 1994-06-02 1996-12-17 The University Of North Carolina At Chapel Hill Isolated DNA encoding c-mer protooncogene
ES2263152T3 (en) * 1994-06-09 2006-12-01 Licentia Oy MONOCLONAL ANTIBODY AGAINST THE FLT4 THYROSINE KINASE RECEPTOR AND ITS USE IN DIAGNOSIS AND THERAPY.
WO1996009381A1 (en) * 1994-09-22 1996-03-28 Helsinki University Licensing Ltd. Oy Promoter for the receptor tyrosine kinase, tie
US5722638A (en) * 1995-10-20 1998-03-03 Vemco Corporation Valve with means to block relative rotation of parts during assembly
US5972338A (en) 1997-09-19 1999-10-26 Genentech, Inc. Tie ligands homologues
US6057435A (en) * 1997-09-19 2000-05-02 Genentech, Inc. Tie ligand homologues
US6350450B1 (en) 1997-09-19 2002-02-26 Genentech, Inc. TIE ligand homologue antibody
US6030831A (en) * 1997-09-19 2000-02-29 Genetech, Inc. Tie ligand homologues
US6348350B1 (en) 1997-09-19 2002-02-19 Genentech, Inc. Ligand homologues
US6365154B1 (en) * 1998-09-28 2002-04-02 Smithkline Beecham Corporation Tie2 agonist antibodies
ES2357406T3 (en) 1998-10-09 2011-04-26 Vegenics Limited Flt4 (VEGFR-3) AS A DIANA FOR OBTAINING IMAGES OF TUMORS AND ANTITUMORAL THERAPY.
US7396810B1 (en) 2000-08-14 2008-07-08 Oregon Health Sciences University Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
NZ516258A (en) 1999-06-07 2004-02-27 Immunex Corp Tek antagonists
US6521424B2 (en) 1999-06-07 2003-02-18 Immunex Corporation Recombinant expression of Tek antagonists
EP1956030B1 (en) 1999-06-15 2009-11-11 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids endoding the same
AU2002248372B8 (en) 2001-01-19 2008-03-20 Vegenics Limited FLT4(VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US7871610B2 (en) 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
JP2007528720A (en) 2003-08-12 2007-10-18 ダイアックス コーポレイション TIE1 binding ligand
US7485297B2 (en) 2003-08-12 2009-02-03 Dyax Corp. Method of inhibition of vascular development using an antibody
MX368730B (en) 2013-02-18 2019-10-14 Vegenics Pty Ltd Ligand binding molecules and uses thereof.

Also Published As

Publication number Publication date
WO1993014124A1 (en) 1993-07-22
CA2127540A1 (en) 1993-07-22
EP0620826A1 (en) 1994-10-26
AU3353293A (en) 1993-08-03
KR940703857A (en) 1994-12-12
HUT69792A (en) 1995-09-28
FI943275A0 (en) 1994-07-08
HU9402057D0 (en) 1994-09-28
JPH07506242A (en) 1995-07-13

Similar Documents

Publication Publication Date Title
FI943275A0 (en) TIE, a novel endothelial cell receptor tyrosine kinase
FI952064A0 (en) Tachykinin receptor antagonists without peptidyl structure
FI960227A (en) 2,8-disubstituted quinazolinones
NO944421L (en) Substituted 1,2,3,4-tetrahydroisoquinolines with angiotensin II receptor activity
TR199700334T1 (en) Indolyl neuropeptide y receptor antagonists.
NO985293L (en) New 2,3-disubstituted-4 (3H) -quinazolinones
DE58902481D1 (en) 1,3-DISUBSTITUTED PYRROLIDINE.
FI921708A (en) STOLSTOPPNING, SPECIELLT FLYGPLANSFAOTOELJ
FI922494A (en) PULVERFORM, ENZYMER INNEHAOLLANDE DISKMEDELSKOMPOSITION FOER AUTOMATISKA DISKMASKINER
FR2666610B1 (en) SUPPORT FOR GUARDRAIL POST.
FI922654A (en) SEEKRINGSANORDNING FOER AVTRYCKARMEKANISMER, ISYNNERHET FOER ELDVAPEN
DE59206461D1 (en) Sizing scaffolding group
NO931364L (en) TACHYKININE RECEPTOR ANTAGONISTS, ISOQINOLONS AND THEIR PREPARATION
NO932588D0 (en) STORAGE STABLE, POLYMER-MODIFIED ASPHALT
FI925411A0 (en) FARTYG, SPECIELLT HANDELSFARTYG
NO881565L (en) STAND, SPECIAL SKIP.
FI921759A (en) LINEAER VISKOELASTISK VATTENHALTIG FLYTANDE DETERGENTKOMPOSITION, SPECIELLT FOER AUTOMATISKA DISKMASKINER
FI923542A (en) FAESTANORDNING FOER KLINGOR, ISYNNERHET I BESTRYKNINGSMASKINER
FI924395A (en) ICKE-A, ICKE-B-PEPTIDER
DE69815072D1 (en) SUBSTITUTED 2,4-DIAMINOPYRIMIDINE
FR2673080B1 (en) REVERSIBLE TIE.
FI924789A (en) GAMMA-INTERFERONERS LOESLIGA, STYMPADE RECEPTOR
KR930012808U (en) Prefab tie holder
FR2675183B1 (en) GUARDRAIL SUPPORT, ESPECIALLY FOR FORMWORK BENCH.
FR2735103B1 (en) SUPPORT FOR SCAFFOLDING ELEMENTS.

Legal Events

Date Code Title Description
FD Application lapsed