FI925069A - NERVSKYDDANDE INDOLON OCH NAERA ANSLUTANDE DERIVAT - Google Patents

NERVSKYDDANDE INDOLON OCH NAERA ANSLUTANDE DERIVAT Download PDF

Info

Publication number
FI925069A
FI925069A FI925069A FI925069A FI925069A FI 925069 A FI925069 A FI 925069A FI 925069 A FI925069 A FI 925069A FI 925069 A FI925069 A FI 925069A FI 925069 A FI925069 A FI 925069A
Authority
FI
Finland
Prior art keywords
pct
nervskyddande
naera
anslutande
indolon
Prior art date
Application number
FI925069A
Other languages
Finnish (fi)
Other versions
FI109121B (en
FI925069A0 (en
Inventor
Bertrand Leo Chenard
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI925069A publication Critical patent/FI925069A/en
Publication of FI925069A0 publication Critical patent/FI925069A0/en
Priority to FI982654A priority Critical patent/FI982654A/en
Application granted granted Critical
Publication of FI109121B publication Critical patent/FI109121B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PCT No. PCT/US91/01470 Sec. 371 Date Nov. 6, 1992 Sec. 102(e) Date Nov. 6, 1992 PCT Filed Mar. 4, 1991 PCT Pub. No. WO91/17156 PCT Pub. Date Nov. 14, 1991.5-(1-Hydroxy-2-piperidinopropyl)-2(1H,3H)-indolone derivatives and analogs; pharmaceutical compositions thereof; methods of treating CNS disorders therewith; and intermediates useful in the preparation of said compounds.
FI925069A 1990-05-10 1992-11-09 Process for the preparation of therapeutically active analogs of 5- (1-hydroxy-2-piperidinopropyl) -2- (1H, 3H) -indolone FI109121B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI982654A FI982654A (en) 1990-05-10 1998-12-08 Nervous protective indolone and closely related derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US52233290A 1990-05-10 1990-05-10
US52233290 1990-05-10
PCT/US1991/001470 WO1991017156A1 (en) 1990-05-10 1991-03-04 Neuroprotective indolone and related derivatives
US9101470 1991-03-04

Publications (3)

Publication Number Publication Date
FI925069A true FI925069A (en) 1992-11-09
FI925069A0 FI925069A0 (en) 1992-11-09
FI109121B FI109121B (en) 2002-05-31

Family

ID=24080448

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925069A FI109121B (en) 1990-05-10 1992-11-09 Process for the preparation of therapeutically active analogs of 5- (1-hydroxy-2-piperidinopropyl) -2- (1H, 3H) -indolone

Country Status (30)

Country Link
US (1) US5306723A (en)
EP (1) EP0554247B1 (en)
JP (1) JPH0699423B2 (en)
KR (1) KR0163355B1 (en)
CN (1) CN1037439C (en)
AT (1) ATE192149T1 (en)
AU (1) AU642994B2 (en)
BR (1) BR9106432A (en)
CA (1) CA2080475C (en)
CZ (1) CZ280560B6 (en)
DE (1) DE69132141T2 (en)
DK (1) DK0554247T3 (en)
EG (1) EG19647A (en)
ES (1) ES2146578T3 (en)
FI (1) FI109121B (en)
GR (1) GR3034005T3 (en)
HU (1) HU221193B1 (en)
IE (1) IE911569A1 (en)
IL (1) IL98056A (en)
MY (1) MY107799A (en)
NO (1) NO301979B1 (en)
PH (1) PH29902A (en)
PL (1) PL169267B1 (en)
PT (1) PT97602B (en)
RU (1) RU2068414C1 (en)
SK (1) SK280833B6 (en)
TW (1) TW198720B (en)
WO (1) WO1991017156A1 (en)
YU (1) YU48528B (en)
ZA (1) ZA913494B (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2108557A1 (en) * 1991-04-18 1992-10-19 Bertrand L. Chenard Prodrug esters of phenolic 2-piperidino-1-alkanols
US5594007A (en) * 1991-04-18 1997-01-14 Pfizer Inc. Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols
PL169884B1 (en) * 1991-07-17 1996-09-30 Pfizer Method of obtaining novel 2-(4-hydroxypiperidino)-1-alkanolic derivatives
FR2688504B1 (en) * 1992-03-13 1995-05-05 Synthelabo DERIVATIVES OF 2- (PIPERIDIN-1-YL) ETHANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
US5319096A (en) * 1992-04-03 1994-06-07 Hoechst-Roussel Pharmaceuticals Inc. (1H-indol-1-yl)-2-(amino) acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use
US6255322B1 (en) 1992-06-19 2001-07-03 Pfizer Inc. 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
NZ255074A (en) * 1992-10-30 1996-10-28 Pfizer 6-[2-(4-hydroxy-4-(4-substituted phenyl)piperidino)-1-hydroxypropyl]-3,4-dihydro-2(1h)-quinolones
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
KR100224961B1 (en) * 1994-08-18 1999-10-15 디. 제이. 우드 Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydrophenyl)-2-(piperidinyl-1)-alkanol derivatives
GB9510459D0 (en) 1995-05-24 1995-07-19 Zeneca Ltd Bicyclic amines
ZA9610738B (en) * 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
TW427978B (en) * 1996-02-03 2001-04-01 Hoffmann La Roche Tetrahydroisoquinoline derivatives
CA2251851A1 (en) * 1996-05-13 1997-11-20 Roger Salmon Bicyclic amines as insecticides
GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
GB9624611D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Bicyclic amine compounds
TR199901704T2 (en) 1996-11-26 1999-12-21 Zeneca Limited 8-azabicyclo $ 3.2.1] octan-, 8-azabicyclo $ 3.2.1] oct-6-en-, 9-azabicyclo $ 3.3.1] nonan-, 9-aza-3-oxabicyclo $ 3.3.1] nonan-ve 9- aza-3-tiabicyclo $ 3.3.1] breadcrumbs, which are not prepared and used as insecticides.
EP0846683B1 (en) * 1996-12-03 2001-09-19 F. Hoffmann-La Roche Ag 4-Hydroxy-piperidine derivatives
CA2220649C (en) 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
EP1173254A2 (en) * 1999-04-27 2002-01-23 Smithkline Beecham Plc Novel treatment of neurotraumatic conditions with a raf inhibitor
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6362196B1 (en) 1999-10-29 2002-03-26 Merck & Co., Inc. Method to treat pain utilizing benzimidazole NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
IL157254A0 (en) 2001-02-23 2004-02-19 Merck & Co Inc N-substituted nonaryl-heterocyclic nmda/mr2b antagonists
WO2002080928A1 (en) * 2001-04-03 2002-10-17 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists
EP1472248A1 (en) * 2002-01-17 2004-11-03 Eli Lilly And Company Modulators of acetylcholine receptors
US6713490B2 (en) 2002-04-26 2004-03-30 Pfizer, Inc. 3,4-dihydroquinolin-2(1H)-one compounds as NR2B receptor antagonists
EP1673367A1 (en) * 2003-10-08 2006-06-28 Pfizer, Inc. Fused lactam compounds
EP1838705A2 (en) * 2005-01-13 2007-10-03 Neurosearch A/S 3,8-substituted 8-aza-bicyclo [3.2.1] octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US20220218640A1 (en) 2021-01-14 2022-07-14 Rob Dickerman Amino acid delivery system

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294804A (en) * 1961-01-27 1966-12-27 Sterling Drug Inc 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propionoxy-piperidine
FR5733M (en) * 1966-09-27 1968-01-22
JPS51118772A (en) * 1975-04-09 1976-10-18 Otsuka Pharmaceut Co Ltd Method for preparing carbostyryl derivatives
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
US4358456A (en) * 1980-05-03 1982-11-09 John Wyeth & Brother Limited Antipsychotic piperidinomethyl-indole derivatives
DE3045688A1 (en) * 1980-12-04 1982-07-08 C.H. Boehringer Sohn, 6507 Ingelheim NEW 8-ARYLALKYL-3-PHENYL-3-NORTROPANOLE, THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
JPS57142972A (en) * 1981-02-27 1982-09-03 Otsuka Pharmaceut Co Ltd Carbostyril derivative
FR2534580A1 (en) * 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
FR2546166B1 (en) * 1983-05-19 1985-10-25 Synthelabo ENANTIOMERS OF ERYTHRO (BENZYL-4 PIPERIDINO) -2 (HYDROXY-4 OR BENZYLOXY-4 PHENYL) -1 PROPANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2581993B1 (en) * 1985-05-14 1988-03-18 Synthelabo (BENZOYL-4 PIPERIDINO) -2 PHENYL-1 ALCANOLS DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
KR910006138B1 (en) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 Cyclic amine derivatives
EP0322361A3 (en) * 1987-12-23 1990-01-24 Ciba-Geigy Ag Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds
FR2640266B2 (en) * 1988-07-12 1992-07-10 Synthelabo INDOLONES-2, QUINOLEINONES-2, BENZO (B) AZEPINONES-2 AND BENZIMIDAZOLONES-2 DERIVATIVES OF (HYDROXY-1 PIPERIDINYL-2 ALKYL), THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
ES2098248T3 (en) * 1989-05-17 1997-05-01 Pfizer DERIVATIVES OF 2-PIPERIDINE-1-ALCANOLS AS ANTI-ISCHEMICAL AGENTS.

Also Published As

Publication number Publication date
ZA913494B (en) 1992-12-30
NO924310L (en) 1992-11-09
CA2080475C (en) 2001-04-17
EP0554247A1 (en) 1993-08-11
CZ280560B6 (en) 1996-02-14
ES2146578T3 (en) 2000-08-16
EG19647A (en) 1995-08-30
MY107799A (en) 1996-06-29
RU2068414C1 (en) 1996-10-27
SK280833B6 (en) 2000-08-14
IL98056A (en) 1995-11-27
CA2080475A1 (en) 1991-11-11
AU7456591A (en) 1991-11-27
KR930700482A (en) 1993-03-15
CN1037439C (en) 1998-02-18
DE69132141D1 (en) 2000-05-31
DE69132141T2 (en) 2000-09-21
CN1056497A (en) 1991-11-27
WO1991017156A1 (en) 1991-11-14
YU81091A (en) 1993-11-16
FI109121B (en) 2002-05-31
IL98056A0 (en) 1992-06-21
YU48528B (en) 1998-11-05
PT97602B (en) 1998-08-31
PH29902A (en) 1996-09-16
FI925069A0 (en) 1992-11-09
AU642994B2 (en) 1993-11-04
BR9106432A (en) 1993-05-04
PT97602A (en) 1992-02-28
GR3034005T3 (en) 2000-11-30
ATE192149T1 (en) 2000-05-15
HUT62879A (en) 1993-06-28
US5306723A (en) 1994-04-26
KR0163355B1 (en) 1998-12-01
HU9203515D0 (en) 1993-01-28
HU221193B1 (en) 2002-08-28
EP0554247B1 (en) 2000-04-26
NO924310D0 (en) 1992-11-09
IE911569A1 (en) 1991-11-20
NO301979B1 (en) 1998-01-05
DK0554247T3 (en) 2000-08-07
PL169267B1 (en) 1996-06-28
TW198720B (en) 1993-01-21
JPH0699423B2 (en) 1994-12-07
JPH05506433A (en) 1993-09-22
CS135491A3 (en) 1992-05-13

Similar Documents

Publication Publication Date Title
FI925069A0 (en) NERVSKYDDANDE INDOLON OCH NAERA ANSLUTANDE DERIVAT
FI925820A (en) BISBENSO- ELLER BENSOPYRODCYKLOHEPTAPIPERIDEN-, PIPERIDYLIDEN OCH PIERATZINFOERENINGAR OCH -COSPOSITIONER
FI853625A0 (en) TETRAL LINES, DERAS FRAMSTAELLNING OCH ANVAENDNING.
DE69516503D1 (en) PIPERIDE DERIVATIVES WITH PAF ANTAGONISTIC EFFECT
FI853624A0 (en) 1-SUBSTITUTE TETRALINDERIVAT, DERAS FRAMSTAELLNING OCH ANVAENDNING.
FI962323A0 (en) N-substituted azabicycloheptane derivatives, such as e.g. neuroleptic
DK0545983T3 (en) Intermediate products for chelating agents with predetermined symmetry as well as process for their preparation
DK0515540T3 (en) Derivative of beta-phenylisoserine, its preparation and use
ES2102026T3 (en) BRIDGED BIS-ARYL-CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE.
MX9303605A (en) DERIVATIVES OF AZABICICLOHEPTANO N-SUBSTITUTED, ITS OBTAINING AND USE.
ES2120445T3 (en) 5-AMINOALKYL-SUBSTITUTED MERCAPTOTIAZOLES, THEIR OBTAINING AND EMPLOYMENT.
ES2098119T3 (en) NEW TRIAZOLOQUINAZOLINES, THEIR OBTAINING AND EMPLOYMENT.
ES2095058T3 (en) DERIVATIVES OF 3-AZABICICLO (3.2.0) HEPTANE SUBSTITUTED AS INTERMEDIATE PRODUCTS.
KR950700270A (en) Mixtures of Optically Active Cyclohexenone Oxime Ethers, Process and Intermediate Products for Their Production and Their Use as Herbicides
FI933883A (en) NYA 1-ARYL-4-PIPERAZINYL-CYCLOHEXANKARBOXYLSYRANITRILER, DERAS FRAMSTAELLNING OCH ANVAENDNING

Legal Events

Date Code Title Description
MA Patent expired