FI924460A0 - HMG-COA-REDUCTIVE INHIBITORER - Google Patents

HMG-COA-REDUCTIVE INHIBITORER

Info

Publication number
FI924460A0
FI924460A0 FI924460A FI924460A FI924460A0 FI 924460 A0 FI924460 A0 FI 924460A0 FI 924460 A FI924460 A FI 924460A FI 924460 A FI924460 A FI 924460A FI 924460 A0 FI924460 A0 FI 924460A0
Authority
FI
Finland
Prior art keywords
inhibitorer
hmg
coa
reductive
reductive inhibitorer
Prior art date
Application number
FI924460A
Other languages
Finnish (fi)
Other versions
FI924460A (en
Inventor
Christopher Norman Lewis
Alan Hornsby Davidson
Richard Simon Todd
Original Assignee
British Bio Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Bio Technology filed Critical British Bio Technology
Publication of FI924460A0 publication Critical patent/FI924460A0/en
Publication of FI924460A publication Critical patent/FI924460A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI924460A 1990-04-05 1992-10-02 HMG-COA-REDUCTIVE INHIBITORER FI924460A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909007738A GB9007738D0 (en) 1990-04-05 1990-04-05 Compounds
PCT/GB1991/000357 WO1991015482A1 (en) 1990-04-05 1991-03-07 Hmg-co a reductive inhibitors

Publications (2)

Publication Number Publication Date
FI924460A0 true FI924460A0 (en) 1992-10-02
FI924460A FI924460A (en) 1992-10-02

Family

ID=10673960

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924460A FI924460A (en) 1990-04-05 1992-10-02 HMG-COA-REDUCTIVE INHIBITORER

Country Status (11)

Country Link
EP (1) EP0524190A1 (en)
JP (1) JPH05505603A (en)
AU (1) AU657263B2 (en)
CA (1) CA2078888A1 (en)
FI (1) FI924460A (en)
GB (1) GB9007738D0 (en)
IE (1) IE911089A1 (en)
NZ (1) NZ237663A (en)
PT (1) PT97241A (en)
WO (1) WO1991015482A1 (en)
ZA (1) ZA912509B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ250609A (en) * 1992-12-28 1995-07-26 Sankyo Co Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX7065E (en) * 1980-06-06 1987-04-10 Sankyo Co A MICROBIOLOGICAL PROCEDURE FOR PREPARING DERIVATIVES OF ML-236B
JPS57185275A (en) * 1981-05-07 1982-11-15 Sankyo Co Ltd Tetrahydro-dum-4 and tetrahydro-isodum-4 and their derivatives
PT88364A (en) * 1987-09-02 1989-07-31 Merck & Co Inc PROCESS FOR PREPARING NOVEL HMG-COA REDUCTASE INHIBITORS
US4916239A (en) * 1988-07-19 1990-04-10 Merck & Co., Inc. Process for the lactonization of mevinic acids and analogs thereof

Also Published As

Publication number Publication date
EP0524190A1 (en) 1993-01-27
GB9007738D0 (en) 1990-06-06
PT97241A (en) 1991-12-31
NZ237663A (en) 1993-07-27
IE911089A1 (en) 1991-10-09
ZA912509B (en) 1992-12-30
AU657263B2 (en) 1995-03-09
CA2078888A1 (en) 1991-10-06
AU7345791A (en) 1991-10-30
FI924460A (en) 1992-10-02
WO1991015482A1 (en) 1991-10-17
JPH05505603A (en) 1993-08-19

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