FI922798A0 - ANALYZING AV GABA-B-SELECTIVE AGONISTER SAOSOM HOSTMEDICINER. - Google Patents

ANALYZING AV GABA-B-SELECTIVE AGONISTER SAOSOM HOSTMEDICINER.

Info

Publication number
FI922798A0
FI922798A0 FI922798A FI922798A FI922798A0 FI 922798 A0 FI922798 A0 FI 922798A0 FI 922798 A FI922798 A FI 922798A FI 922798 A FI922798 A FI 922798A FI 922798 A0 FI922798 A0 FI 922798A0
Authority
FI
Finland
Prior art keywords
gaba
selective
hostmediciner
agonister
saosom
Prior art date
Application number
FI922798A
Other languages
Finnish (fi)
Other versions
FI922798A (en
Inventor
William Kreutner
Donald Bolser
Richard Chapman
Sultan Aziz
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI922798A publication Critical patent/FI922798A/en
Publication of FI922798A0 publication Critical patent/FI922798A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A method for treating cough in a mammal comprising administering to said mammal an anti-tussive effective amount of a GABA-B selective agonist such as <IMAGE> is described.
FI922798A 1989-12-20 1992-06-17 ANALYZING AV GABA-B-SELECTIVE AGONISTER SAOSOM HOSTMEDICINER. FI922798A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/454,786 US5006560A (en) 1989-12-20 1989-12-20 Use of GABA-B selective agonists as anti-tussive agents
PCT/US1990/007290 WO1991008740A1 (en) 1989-12-20 1990-12-18 The use of gaba-b selective agonists as anti-tussive agents

Publications (2)

Publication Number Publication Date
FI922798A FI922798A (en) 1992-06-17
FI922798A0 true FI922798A0 (en) 1992-06-17

Family

ID=23806078

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922798A FI922798A0 (en) 1989-12-20 1992-06-17 ANALYZING AV GABA-B-SELECTIVE AGONISTER SAOSOM HOSTMEDICINER.

Country Status (14)

Country Link
US (1) US5006560A (en)
EP (1) EP0506853B1 (en)
JP (1) JPH06102630B2 (en)
KR (1) KR950007208B1 (en)
AT (1) ATE106725T1 (en)
AU (1) AU642969B2 (en)
CA (1) CA2071981C (en)
DE (1) DE69009778T2 (en)
DK (1) DK0506853T3 (en)
ES (1) ES2055587T3 (en)
FI (1) FI922798A0 (en)
HU (1) HU212271B (en)
OA (1) OA09702A (en)
WO (1) WO1991008740A1 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229404A (en) * 1988-05-18 1993-07-20 Novo Nordisk A/S Azacyclic carboxylic acid derivatives and their preparation and use
US5214054A (en) * 1988-05-18 1993-05-25 Novo Nordisk A/S Azacyclic carboxylic acid derivatives and their preparation and use
US5231106A (en) * 1988-05-18 1993-07-27 Novo Nordisk A/S Azacyclic carboxylic acid derivatives and their preparation and use
DK588189D0 (en) * 1989-11-22 1989-11-22 Novo Nordisk As NEW HETEROCYCLIC CARBOXYLIC ACIDS
US5182266A (en) * 1990-01-31 1993-01-26 Abbott Laboratories Method for treating renal disease
FR2662354B1 (en) * 1990-05-23 1994-10-07 Adir USE OF BACLOFENE FOR OBTAINING MEDICINAL PRODUCTS FOR THE TREATMENT OF ANGINA OF CHEST.
GB9117716D0 (en) * 1991-08-16 1991-10-02 Lynxvale Ltd Gaba derivatives and their therapeutic application
US6194460B1 (en) * 1995-05-31 2001-02-27 Montefiore Medical Center Composition for treating cough induced by angiotensin converting enzyme inhibitors
DE69738396T2 (en) * 1996-05-24 2008-12-04 Smithkline Beecham Corp. USE OF GABA RECORD INHIBITORS AS AGENTS AGAINST HUSTEN
IL139298A0 (en) * 1998-05-15 2001-11-25 Warner Lambert Co Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
SE9904508D0 (en) 1999-12-09 1999-12-09 Astra Ab New compounds
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
PT1660440E (en) 2003-08-20 2012-05-15 Xenoport Inc Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
US7494985B2 (en) * 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
WO2006050471A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US20060160777A1 (en) * 2004-12-27 2006-07-20 Anders Lehmann New use of GABAbeta receptor agonists
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
CA2674610C (en) * 2007-01-11 2013-06-18 Xenoport, Inc. Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment
US20090118365A1 (en) * 2007-11-06 2009-05-07 Xenoport, Inc Use of Prodrugs of GABA B Agonists for Treating Neuropathic and Musculoskeletal Pain
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
EP2250148B1 (en) * 2008-01-25 2016-08-17 XenoPort, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use
TWI369202B (en) * 2008-01-25 2012-08-01 Xenoport Inc Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
US20100137442A2 (en) * 2008-02-01 2010-06-03 Xenoport, Inc. Sustained Release Particulate Oral Dosage Forms of (R)-Baclofen and Methods of Treatment
US9623000B2 (en) 2008-07-31 2017-04-18 Dekel Pharmaceuticals Ltd Compositions and methods for treating inflammatory disorders
US8299291B2 (en) * 2008-08-07 2012-10-30 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
US7989641B2 (en) 2008-08-07 2011-08-02 Xenoport, Inc. Methods of synthesizing N-hydroxysuccinimidyl carbonates
NZ594648A (en) 2009-03-03 2013-12-20 Xenoport Inc Sustained release oral dosage forms of an r-baclofen prodrug
CA2758245A1 (en) * 2009-04-17 2010-10-21 Xenoport, Inc. Gamma-amino-butyric acid derivatives as gabab receptor ligands
WO2013023155A1 (en) 2011-08-11 2013-02-14 Xenoport, Inc. Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH449645A (en) * 1963-07-09 1968-01-15 Ciba Geigy Process for the production of new amino acids

Also Published As

Publication number Publication date
FI922798A (en) 1992-06-17
OA09702A (en) 1993-08-30
ES2055587T3 (en) 1994-08-16
CA2071981A1 (en) 1991-06-21
EP0506853B1 (en) 1994-06-08
JPH06102630B2 (en) 1994-12-14
EP0506853A1 (en) 1992-10-07
DE69009778T2 (en) 1994-09-22
AU7174591A (en) 1991-07-18
KR950007208B1 (en) 1995-07-04
WO1991008740A1 (en) 1991-06-27
JPH05504764A (en) 1993-07-22
HUT61194A (en) 1992-12-28
DE69009778D1 (en) 1994-07-14
KR920703043A (en) 1992-12-17
US5006560A (en) 1991-04-09
HU9202077D0 (en) 1992-09-28
HU212271B (en) 1996-04-29
ATE106725T1 (en) 1994-06-15
CA2071981C (en) 2002-06-25
DK0506853T3 (en) 1994-08-01
AU642969B2 (en) 1993-11-04

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