FI915962A0 - ASYMMETRISK HYDRERING. - Google Patents

ASYMMETRISK HYDRERING.

Info

Publication number
FI915962A0
FI915962A0 FI915962A FI915962A FI915962A0 FI 915962 A0 FI915962 A0 FI 915962A0 FI 915962 A FI915962 A FI 915962A FI 915962 A FI915962 A FI 915962A FI 915962 A0 FI915962 A0 FI 915962A0
Authority
FI
Finland
Prior art keywords
hydrering
asymmetrisk
formula
image
atropisomeric
Prior art date
Application number
FI915962A
Other languages
Finnish (fi)
Other versions
FI915962A (en
Inventor
Emil Albin Broger
Yvo Crameri
Hans Peter Isenring
Albert Pfiffner
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI915962A0 publication Critical patent/FI915962A0/en
Publication of FI915962A publication Critical patent/FI915962A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/02—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by hydrogenation
    • C07C5/10—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by hydrogenation of aromatic six-membered rings
    • C07C5/11—Partial hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/20—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Abstract

A process for the asymmetric hydrogenation of (E)-2-methyl-3-phenyl-2-propen-1-ol of the formula <IMAGE> in which R1 has the meaning mentioned herein, to give compounds of the formula <IMAGE> is described. The catalyst used is a neutral or cationic Rh complex of an atropisomeric phosphine.
FI915962A 1990-12-21 1991-12-18 ASYMMETRISK HYDRERING. FI915962A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH410090 1990-12-21

Publications (2)

Publication Number Publication Date
FI915962A0 true FI915962A0 (en) 1991-12-18
FI915962A FI915962A (en) 1992-06-22

Family

ID=4269826

Family Applications (1)

Application Number Title Priority Date Filing Date
FI915962A FI915962A (en) 1990-12-21 1991-12-18 ASYMMETRISK HYDRERING.

Country Status (16)

Country Link
EP (1) EP0492401B1 (en)
JP (1) JPH04295440A (en)
KR (1) KR920011975A (en)
AT (1) ATE133403T1 (en)
CA (1) CA2058112A1 (en)
CZ (1) CZ280199B6 (en)
DE (1) DE59107308D1 (en)
DK (1) DK0492401T3 (en)
ES (1) ES2082104T3 (en)
FI (1) FI915962A (en)
GR (1) GR3018831T3 (en)
HU (1) HU210521B (en)
IE (1) IE71201B1 (en)
IL (1) IL100431A (en)
MX (1) MX9102682A (en)
TW (1) TW200449B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374727A (en) * 1992-06-19 1994-12-20 Hoffmann-La Roche Inc. Asymmetric hydrogenation of dihydro-pyrido [1,2-a]indoles
IT1276165B1 (en) 1995-11-24 1997-10-27 Caffaro Spa Ind Chim PROCEDURE FOR ENANTIOSELECTIVE SYNTHESIS OF CHIRAL DERIVATIVES OF S-3- (4'-TERT-BUTYL) -PHENYL-2-METHYL PROPYLAMINE, SYSTEMIC FUNGICIDES
EP0974590A1 (en) * 1998-07-13 2000-01-26 F. Hoffmann-La Roche Ag Process for the preparation of chiral lactones by asymetrical hydrogenation
US6222039B1 (en) 1998-07-13 2001-04-24 Hoffman-La Roche Inc. Process for the preparation of chiral lactones
DE102004047836A1 (en) 2004-09-29 2006-03-30 Basf Ag Process for the preparation of optically active 2-methylalkanols
ATE451345T1 (en) * 2005-03-17 2009-12-15 Basf Se METHOD FOR PRODUCING OPTICALLY ACTIVE 3-PHENYLPROPIONIC ACID DERIVATIVES AND SEQUENTIAL PRODUCTS THEREOF

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354187B (en) * 1976-11-22 1979-12-27 Hoffmann La Roche FUNGICIDE AGENT
DE3001303A1 (en) * 1980-01-16 1981-07-23 Basf Ag, 6700 Ludwigshafen OPTICALLY ACTIVE PHENYL PROPANE DERIVATIVES, THEIR PRODUCTION AND USE

Also Published As

Publication number Publication date
GR3018831T3 (en) 1996-04-30
IL100431A (en) 1995-12-31
CZ280199B6 (en) 1995-11-15
ATE133403T1 (en) 1996-02-15
HUT59650A (en) 1992-06-29
EP0492401A1 (en) 1992-07-01
TW200449B (en) 1993-02-21
MX9102682A (en) 1992-06-01
DK0492401T3 (en) 1996-03-04
ES2082104T3 (en) 1996-03-16
IL100431A0 (en) 1992-09-06
CA2058112A1 (en) 1992-06-22
EP0492401B1 (en) 1996-01-24
IE71201B1 (en) 1997-02-12
IE914509A1 (en) 1992-07-01
HU210521B (en) 1995-04-28
FI915962A (en) 1992-06-22
KR920011975A (en) 1992-07-25
JPH04295440A (en) 1992-10-20
HU914088D0 (en) 1992-03-30
DE59107308D1 (en) 1996-03-07
CS387591A3 (en) 1992-07-15

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Owner name: NOVARTIS AG

FD Application lapsed