FI914228A0 - AZACYKLISKA FOERENINGAR. - Google Patents

AZACYKLISKA FOERENINGAR.

Info

Publication number
FI914228A0
FI914228A0 FI914228A FI914228A FI914228A0 FI 914228 A0 FI914228 A0 FI 914228A0 FI 914228 A FI914228 A FI 914228A FI 914228 A FI914228 A FI 914228A FI 914228 A0 FI914228 A0 FI 914228A0
Authority
FI
Finland
Prior art keywords
azacykliska
foereningar
azacykliska foereningar
Prior art date
Application number
FI914228A
Other languages
Finnish (fi)
Other versions
FI914228A (en
Inventor
Franz Ostermayer
Peter Herold
Walter Fuhrer
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of FI914228A0 publication Critical patent/FI914228A0/en
Publication of FI914228A publication Critical patent/FI914228A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
FI914228A 1990-09-10 1991-09-06 AZACYKLISKA FOERENINGAR. FI914228A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH292790 1990-09-10

Publications (2)

Publication Number Publication Date
FI914228A0 true FI914228A0 (en) 1991-09-06
FI914228A FI914228A (en) 1992-03-11

Family

ID=4244763

Family Applications (1)

Application Number Title Priority Date Filing Date
FI914228A FI914228A (en) 1990-09-10 1991-09-06 AZACYKLISKA FOERENINGAR.

Country Status (12)

Country Link
EP (1) EP0475898A1 (en)
JP (1) JPH04342571A (en)
KR (1) KR920006323A (en)
AU (1) AU8375591A (en)
CA (1) CA2050769A1 (en)
FI (1) FI914228A (en)
HU (1) HUT59129A (en)
IE (1) IE913165A1 (en)
IL (1) IL99372A0 (en)
NO (1) NO913542L (en)
PT (1) PT98903A (en)
ZA (1) ZA917143B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201738B (en) * 1990-03-20 1993-03-11 Sanofi Co
FR2681067B1 (en) * 1991-09-10 1993-12-17 Elf Sanofi N-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
US5164403A (en) * 1991-04-05 1992-11-17 G. D. Searle & Co. N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
US5436259A (en) * 1991-05-10 1995-07-25 Merck & Co., Inc. Substituted 1,2,4-triazolin-3-one compounds bearing acidic functional groups as balanced angiotensin II antagonists
CA2109524A1 (en) * 1991-05-10 1992-11-11 Prasun K. Chakravarty Acidic aralkyl triazole derivatives active as angiotensin ii antagonists
WO1993004046A1 (en) * 1991-08-19 1993-03-04 E.I. Du Pont De Nemours And Company Angiotensin ii receptor blocking imidazolinone derivatives
WO1993004045A1 (en) * 1991-08-19 1993-03-04 E.I. Du Pont De Nemours And Company Angiotensin ii receptor blocking imidazolinone derivatives
US5182288A (en) * 1991-11-13 1993-01-26 Ortho Pharmaceutical Corporation Substituted n-biphenylyl lactams
DE69328108D1 (en) * 1992-10-13 2000-04-20 Searle & Co N-ARYLHETEROARYLALKYL-1-PHENYL-IMIDAZOL-2-ON COMPOUNDS IN THE TREATMENT OF CIRCULATORY DISORDERS
US5411641A (en) * 1993-11-22 1995-05-02 E. I. Du Pont De Nemours And Company Electrochemical conversion of anhydrous hydrogen halide to halogen gas using a cation-transporting membrane
FR2725987B1 (en) * 1994-10-19 1997-01-10 Sanofi Sa PROCESS FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE IN TWO CRYSTALLINE FORMS AND NOVEL CRYSTALLINE FORM THEREOF
TW442301B (en) * 1995-06-07 2001-06-23 Sanofi Synthelabo Pharmaceutical compositions containing irbesartan
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
US5728834A (en) * 1996-11-14 1998-03-17 Wyckoff Chemical Company, Inc. Process for preparation of 4-aryl-1,2,4-triazol-3-ones
FR2766821A1 (en) * 1997-07-29 1999-02-05 Sanofi Sa 1,3-OXAZOLINYL-BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS SYNTHESIS INTERMEDIATES
GB9716446D0 (en) * 1997-08-05 1997-10-08 Agrevo Uk Ltd Fungicides
US6162922A (en) * 1998-01-30 2000-12-19 Bristol-Myers Squibb Co. Method for preparing N-substituted heterocyclic derivatives using a phase-transfer catalyst
AU4933199A (en) 1998-08-03 2000-02-28 Sumitomo Chemical Company, Limited Triazolone derivatives, use thereof, and intermediate therefor
SE9903028D0 (en) 1999-08-27 1999-08-27 Astra Ab New use
ATE316954T1 (en) * 2002-02-08 2006-02-15 Merck & Co Inc N-BIPHENYLMETHYLAMINOCYCLOALKANE CARBOXAMIDE DERIVATIVE
AR038377A1 (en) * 2002-02-08 2005-01-12 Merck & Co Inc DERIVATIVES OF N-BIFENIL-AMINOCICLOALCANCARBOXAMIDA (WITH REPLACEMENT WITH METHYL)
AU2003265674B2 (en) 2002-08-29 2008-12-11 Merck & Co., Inc. N-biarylmethyl aminocycloalkanecarboxamide derivatives
WO2004089938A1 (en) * 2003-04-07 2004-10-21 Hetero Drugs Limited A novel crystalline form of irbesartan
EP1654232A4 (en) 2003-08-07 2008-11-12 Merck & Co Inc Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides
US20090286990A1 (en) * 2004-05-20 2009-11-19 Reguri Buchi Reddy Process for preparing irbesartan
EP1749828A1 (en) 2005-08-04 2007-02-07 Farmaprojects S.L. Process for preparing an angiotensin II receptor antagonist
WO2007052301A2 (en) * 2005-08-31 2007-05-10 Alembic Limited Process for the preparation of irbesartan
AU2006307471A1 (en) 2005-10-28 2007-05-03 Alembic Limited An improved process for preparation of irbesartan
WO2007122508A2 (en) * 2006-04-24 2007-11-01 Aurobindo Pharma Limited An improved process for the preparation of irbesartan
MX2009013293A (en) 2007-06-04 2010-02-15 Synergy Pharmaceuticals Inc Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2627848T3 (en) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (en) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders
EP2194050A1 (en) 2008-12-08 2010-06-09 KRKA, tovarna zdravil, d.d., Novo mesto A new process for the preparation of irbesartan
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
JP2016514671A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists and uses thereof
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
KR102272746B1 (en) 2013-06-05 2021-07-08 보슈 헬스 아일랜드 리미티드 Ultra-pure agonists of guanylate cyclase c, method of making and using same
CN108276389B (en) * 2018-02-09 2020-10-16 北京化工大学 Synthetic method of irbesartan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
EP0409332A3 (en) * 1989-07-19 1991-08-07 Merck & Co. Inc. Substituted triazoles as angiotensin ii antagonists
EP0412594B1 (en) * 1989-07-28 1996-01-03 Merck & Co. Inc. Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists

Also Published As

Publication number Publication date
EP0475898A1 (en) 1992-03-18
IL99372A0 (en) 1992-08-18
KR920006323A (en) 1992-04-27
JPH04342571A (en) 1992-11-30
PT98903A (en) 1992-07-31
CA2050769A1 (en) 1992-03-11
HUT59129A (en) 1992-04-28
AU8375591A (en) 1992-03-12
NO913542D0 (en) 1991-09-09
HU912903D0 (en) 1992-01-28
IE913165A1 (en) 1992-03-11
NO913542L (en) 1992-03-11
ZA917143B (en) 1992-04-29
FI914228A (en) 1992-03-11

Similar Documents

Publication Publication Date Title
FI913788A (en) INHIBITORER FOER SERINPROTEASER.
DE69112037T2 (en) WAITTRÄGER.
FI915507A0 (en) ARYLDERIVAT.
FI912443A0 (en) POLYDEXTROSKOMPOSITIONER.
FI914228A0 (en) AZACYKLISKA FOERENINGAR.
FI912927A (en) AMINOBENZODIATSEPINER.
DE69111876T2 (en) Ophthalmometer.
FI914509A0 (en) FAERGANORDNING FOER EN DJUPTRYCKSMASKIN.
DE69110728D1 (en) 8-sulfamylmethylene-2-aminotetraline.
NO911007L (en) BAERELATERNE.
FI914968A0 (en) SMALBANDADE STRAOLNINGSFILTERFILMER.
DE59100113D1 (en) ROLLCONTAINER.
DE69104797D1 (en) 2-substituted-1-hydroxyindoles.
NO905139D0 (en) LOESGODSCONTAINER.
FI903317A0 (en) FOERVARNINGSKORG.
FI905221A (en) RENGOERINGSFOERFARANDE.
FI912827A (en) KRISTALLINA POLYPEPTIDER.
ES1012467Y (en) EGG-CUP.
ES1014067Y (en) BOX-EXHIBITOR.
DE59101556D1 (en) Propellans.
ES1015059Y (en) CAPSULE-LID.
ES1015089Y (en) MUNECO CARICATURA TITERE.
ES1015228Y (en) KIOSKO.
ES1013685Y (en) TURENO PYROTECNICO.
ES1017193Y (en) COVER-BIDET.