FI913853A0 - Produktion av vaerdcellsystem med hoeg expression. - Google Patents

Produktion av vaerdcellsystem med hoeg expression.

Info

Publication number
FI913853A0
FI913853A0 FI913853A FI913853A FI913853A0 FI 913853 A0 FI913853 A0 FI 913853A0 FI 913853 A FI913853 A FI 913853A FI 913853 A FI913853 A FI 913853A FI 913853 A0 FI913853 A0 FI 913853A0
Authority
FI
Finland
Prior art keywords
vaerdcellsystem
produktion
expression
med hoeg
hoeg
Prior art date
Application number
FI913853A
Other languages
English (en)
Inventor
David E Lyons
Arlen R Thomason
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of FI913853A0 publication Critical patent/FI913853A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI913853A 1989-12-15 1991-08-14 Produktion av vaerdcellsystem med hoeg expression. FI913853A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45148589A 1989-12-15 1989-12-15
US62367190A 1990-12-12 1990-12-12
PCT/US1990/007460 WO1991008762A1 (en) 1989-12-15 1990-12-17 Production of biologically active platelet-derived growth factor from high expression host cell systems

Publications (1)

Publication Number Publication Date
FI913853A0 true FI913853A0 (fi) 1991-08-14

Family

ID=27036396

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913853A FI913853A0 (fi) 1989-12-15 1991-08-14 Produktion av vaerdcellsystem med hoeg expression.

Country Status (11)

Country Link
US (1) US5428135A (fi)
EP (1) EP0460189A4 (fi)
JP (1) JPH04503960A (fi)
AU (1) AU651083B2 (fi)
FI (1) FI913853A0 (fi)
IE (1) IE904550A1 (fi)
IL (1) IL96682A0 (fi)
NO (1) NO913178D0 (fi)
NZ (1) NZ236493A (fi)
PT (1) PT96224A (fi)
WO (1) WO1991008762A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems
US5272064A (en) * 1989-12-19 1993-12-21 Amgen Inc. DNA molecules encoding platelet-derived growth factor B chain analogs and method for expression thereof
EP0495638A3 (en) * 1991-01-16 1993-06-02 Schering Corporation Expression of mature pdgf-b in escherichia coli
AU3816593A (en) * 1992-03-30 1993-11-08 Schering Corporation Monomeric platelet-derived growth factor and prevention of stenosis or restenosis
US5444151A (en) * 1992-05-15 1995-08-22 Ludwig Institute For Cancer Research Platelet derived growth factor antagonists
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
US6190704B1 (en) * 1994-09-23 2001-02-20 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Regulation of wound healing by nitric oxide
US20030105007A1 (en) * 1995-06-07 2003-06-05 Andre Beaulieu PDGF-betabeta and fibronectin combined in a solid wound dressing for the treatment of wounds
WO2002050099A2 (en) * 2000-11-27 2002-06-27 Rmf Dictagene S.A. Process for folding chemically synthesized polypeptides
WO2006012154A1 (en) 2004-06-28 2006-02-02 Janssen Pharmaceutica, N.V. A method for detecting reactive metabolites using stable-isotope trapping and mass spectroscopy
US7884186B2 (en) 2006-09-29 2011-02-08 Janssen Pharmaceutica Nv Isotopically labeled trapping agent and method for identifying reactive metabolites

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769328A (en) * 1984-10-12 1988-09-06 Zymogenetics Inc. Expression of biologically active PDGF analogs in yeast
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4849407A (en) * 1986-08-13 1989-07-18 Zymogenetics, Inc. Biologically active mosaic proteins
US5045633A (en) * 1985-02-25 1991-09-03 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4766205A (en) * 1985-11-13 1988-08-23 Beatrice Companies, Inc. Method for isolation of recombinant polypeptides in biologically active forms
DE3751632T2 (de) * 1986-08-13 1996-06-13 Zymogenetics Inc Expression von biologisch-aktiven PDGF-Analogen in eukaryotischen Zellen
WO1988007057A1 (en) * 1987-03-13 1988-09-22 Amgen Inc. Purified platelet-derived growth factor and methods for purification thereof
US5034375A (en) * 1988-08-10 1991-07-23 Institute Of Molecular Biology, Inc. Process of wound healing using PDGF and EGF
DE3834079A1 (de) * 1988-10-06 1990-04-12 Biotechnolog Forschung Gmbh Wachstumstimulierendes pdgf-bb und dessen verwendung sowie ein verfahren zu seiner herstellung und der des monomeren
DE3900770A1 (de) * 1989-01-12 1990-07-26 Juergen Prof Dr Hoppe Verfahren zur herstellung von pdgf-a und pdgf-aa
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems
US5149792A (en) * 1989-12-19 1992-09-22 Amgen Inc. Platelet-derived growth factor B chain analogs

Also Published As

Publication number Publication date
NZ236493A (en) 1993-10-26
US5428135A (en) 1995-06-27
NO913178L (no) 1991-08-14
NO913178D0 (no) 1991-08-14
EP0460189A4 (en) 1993-05-26
EP0460189A1 (en) 1991-12-11
IE904550A1 (en) 1991-06-19
AU7163891A (en) 1991-07-18
JPH04503960A (ja) 1992-07-16
AU651083B2 (en) 1994-07-14
WO1991008762A1 (en) 1991-06-27
IL96682A0 (en) 1991-09-16
PT96224A (pt) 1991-10-15

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Legal Events

Date Code Title Description
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