FI913427A0 - Molecules with antibody joining sites exhibiting stereospecific catalysis - Google Patents

Molecules with antibody joining sites exhibiting stereospecific catalysis

Info

Publication number
FI913427A0
FI913427A0 FI913427A FI913427A FI913427A0 FI 913427 A0 FI913427 A0 FI 913427A0 FI 913427 A FI913427 A FI 913427A FI 913427 A FI913427 A FI 913427A FI 913427 A0 FI913427 A0 FI 913427A0
Authority
FI
Finland
Prior art keywords
molecules
joining sites
sites exhibiting
antibody joining
stereospecific catalysis
Prior art date
Application number
FI913427A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI95928C (en
FI95928B (en
Inventor
Richard A Lerner
Kim Janda
Stephen Benkovic
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of FI913427A0 publication Critical patent/FI913427A0/en
Application granted granted Critical
Publication of FI95928B publication Critical patent/FI95928B/en
Publication of FI95928C publication Critical patent/FI95928C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4087—Esters with arylalkanols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/42—Halides thereof
    • C07F9/425—Acid or estermonohalides thereof, e.g. RP(=X)(YR)(Hal) (X, Y = O, S; R = H, or hydrocarbon group)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI913427A 1989-01-17 1991-07-16 Molecules with antibody binding sites and stereospecific catalysis FI95928C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US29779889A 1989-01-17 1989-01-17
US29779889 1989-01-17
PCT/US1990/000269 WO1990008185A1 (en) 1989-01-17 1990-01-12 Molecules with antibody combining sites that exhibit stereospecific catalysis
US9000269 1990-01-12

Publications (3)

Publication Number Publication Date
FI913427A0 true FI913427A0 (en) 1991-07-16
FI95928B FI95928B (en) 1995-12-29
FI95928C FI95928C (en) 1996-04-10

Family

ID=23147792

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913427A FI95928C (en) 1989-01-17 1991-07-16 Molecules with antibody binding sites and stereospecific catalysis

Country Status (10)

Country Link
EP (1) EP0454778A4 (en)
JP (1) JPH04502708A (en)
KR (1) KR910700334A (en)
AU (1) AU650846B2 (en)
CA (1) CA2007816A1 (en)
FI (1) FI95928C (en)
GR (1) GR900100025A (en)
IE (1) IE63274B1 (en)
PT (1) PT92884B (en)
WO (1) WO1990008185A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229272A (en) * 1989-04-25 1993-07-20 Igen, Inc. Catalytic antibody components
US5236825A (en) * 1989-01-17 1993-08-17 Scripps Clinic And Research Foundation Polyvalent metal ion-containing antibody combining site catalysts
KR101159061B1 (en) * 2001-10-22 2012-06-22 더 스크립스 리서치 인스티튜트 Antibody targeting compounds
CN110950960B (en) * 2019-11-26 2021-05-14 中国农业大学 Preparation method of small molecule compound antibody based on high-throughput sequencing and hybrid hybridoma technology

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659567A (en) * 1984-09-07 1987-04-21 Scripps Clinic & Research Foundation Molecules with antibody combining sites that bind to hydrolytic transition states
US4963355A (en) * 1986-06-23 1990-10-16 Igen, Inc. Production of antibody catalysts
US4792446A (en) * 1986-06-23 1988-12-20 Igen, Inc. Production of antibody catalysts
US5079152A (en) * 1987-05-28 1992-01-07 Scripps Clinic And Research Foundation Antibody combining sites that exhibit stereoselective synthase activity, and methods using the same

Also Published As

Publication number Publication date
EP0454778A4 (en) 1993-10-06
PT92884A (en) 1990-07-31
AU5038290A (en) 1990-08-13
GR900100025A (en) 1991-06-07
JPH04502708A (en) 1992-05-21
EP0454778A1 (en) 1991-11-06
FI95928C (en) 1996-04-10
AU650846B2 (en) 1994-07-07
CA2007816A1 (en) 1990-07-17
FI95928B (en) 1995-12-29
KR910700334A (en) 1991-03-14
IE63274B1 (en) 1995-04-05
PT92884B (en) 1995-12-29
IE900174L (en) 1990-07-17
WO1990008185A1 (en) 1990-07-26

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed