FI892948A - Process for the preparation of therapeutically useful chromane derivatives - Google Patents

Process for the preparation of therapeutically useful chromane derivatives Download PDF

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Publication number
FI892948A
FI892948A FI892948A FI892948A FI892948A FI 892948 A FI892948 A FI 892948A FI 892948 A FI892948 A FI 892948A FI 892948 A FI892948 A FI 892948A FI 892948 A FI892948 A FI 892948A
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
chromane derivatives
chromane
derivatives
Prior art date
Application number
FI892948A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI92824C (en
FI92824B (en
FI892948A0 (en
Inventor
Guenther Haeusler
Rolf Gericke
Hanns Wurziger
Manfred Baumgarth
Ingeborg Lues
Rolf Bergmann
Peyer Jacques De
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3820506A external-priority patent/DE3820506A1/en
Priority claimed from DE3835011A external-priority patent/DE3835011A1/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of FI892948A0 publication Critical patent/FI892948A0/en
Publication of FI892948A publication Critical patent/FI892948A/en
Application granted granted Critical
Publication of FI92824B publication Critical patent/FI92824B/en
Publication of FI92824C publication Critical patent/FI92824C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cosmetics (AREA)
FI892948A 1988-06-16 1989-06-15 Process for the preparation of therapeutically useful chromane derivatives FI92824C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3820506 1988-06-16
DE3820506A DE3820506A1 (en) 1988-06-16 1988-06-16 N-Heterocyclically substituted chroman derivatives and their use as medicaments
DE3835011A DE3835011A1 (en) 1988-10-14 1988-10-14 CHROME DERIVATIVES
DE3835011 1988-10-14

Publications (4)

Publication Number Publication Date
FI892948A0 FI892948A0 (en) 1989-06-15
FI892948A true FI892948A (en) 1989-12-17
FI92824B FI92824B (en) 1994-09-30
FI92824C FI92824C (en) 1995-01-10

Family

ID=25869185

Family Applications (1)

Application Number Title Priority Date Filing Date
FI892948A FI92824C (en) 1988-06-16 1989-06-15 Process for the preparation of therapeutically useful chromane derivatives

Country Status (11)

Country Link
EP (1) EP0346724A1 (en)
JP (1) JPH0240375A (en)
KR (1) KR910000711A (en)
AU (1) AU626549B2 (en)
DK (1) DK296789A (en)
FI (1) FI92824C (en)
HU (1) HUT56096A (en)
IL (1) IL90613A0 (en)
NO (1) NO174391C (en)
NZ (1) NZ229540A (en)
PT (1) PT90864B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835011A1 (en) * 1988-10-14 1990-04-19 Merck Patent Gmbh CHROME DERIVATIVES
FR2621587B1 (en) * 1987-10-12 1990-02-09 Sanofi Sa 2,2-DIMETHYL CHROMENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
DE3918041A1 (en) * 1989-06-02 1990-12-06 Merck Patent Gmbh CHROME DERIVATIVES
GB8924376D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
EP0430621A3 (en) * 1989-11-29 1992-03-04 Beecham Group P.L.C. Process for the preparation of chiral 3,4-epoxy benzopyrans
JP2575226B2 (en) * 1990-05-11 1997-01-22 吉富製薬株式会社 Process for producing optically active 3,4-dihydro-3,4-epoxy-2H-1 benzopyran compound and synthetic intermediate thereof
CA2070243A1 (en) * 1991-06-14 1992-12-15 Akira Shiozawa Chroman derivatives
CA2122494A1 (en) * 1992-11-25 1994-06-09 Paul W. Manley 2,2-dialkyl- and 2,2-dialkyl-3,4-dihydro-3-hydroxy-2h-1- benzopyrans
WO1994012493A1 (en) * 1992-11-25 1994-06-09 Sandoz, Ltd. 2,2-dialkyl- and 2,2-dialkyl-3,4-dihydro-3-hydroxy-2h-1-benzopyr ans, their use as pharmaceuticals
IL108841A0 (en) * 1993-03-10 1994-06-24 Pfizer Res & Dev Benzopyrans
GB9316111D0 (en) * 1993-08-04 1993-09-22 Pfizer Ltd Benzopyrans
US5574049A (en) * 1994-07-22 1996-11-12 Sandoz Ltd. 2,2-dialkyl- and 2,2-dialkyl-3,4-dihydro-3-hydroxy-2H-1-benzopyrans
JP2007000772A (en) * 2005-06-23 2007-01-11 Casio Electronics Co Ltd Dual microcapsule, method for preparing the same, and method for surface treatment of microcapsule

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107706A (en) * 1981-09-25 1983-05-05 Beecham Group Plc Benzopyrans
EP0107423B1 (en) * 1982-10-19 1986-07-23 Beecham Group Plc Novel chromans and chromenes
PT84806B (en) * 1986-05-03 1989-12-29 Beecham Group Plc PROCESS FOR THE PREPARATION OF BENZOPYRANES
DE3726261A1 (en) * 1986-12-23 1988-07-07 Merck Patent Gmbh CHROME DERIVATIVES
FR2615191B1 (en) * 1987-05-16 1991-01-11 Sandoz Sa NOVEL BENZO (B) PYRANS AND PYRANNOPYRIDINES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2621587B1 (en) * 1987-10-12 1990-02-09 Sanofi Sa 2,2-DIMETHYL CHROMENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives

Also Published As

Publication number Publication date
KR910000711A (en) 1991-01-30
PT90864B (en) 1994-11-30
HUT56096A (en) 1991-07-29
IL90613A0 (en) 1990-01-18
AU3644089A (en) 1989-12-21
FI92824C (en) 1995-01-10
DK296789D0 (en) 1989-06-15
EP0346724A1 (en) 1989-12-20
DK296789A (en) 1989-12-17
FI92824B (en) 1994-09-30
NO892494L (en) 1989-12-18
NO174391B (en) 1994-01-17
FI892948A0 (en) 1989-06-15
PT90864A (en) 1989-12-29
NZ229540A (en) 1991-03-26
AU626549B2 (en) 1992-08-06
NO892494D0 (en) 1989-06-15
JPH0240375A (en) 1990-02-09
NO174391C (en) 1994-04-27

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUN