FI890946A - Framstaellning av starkt exprimerande rekombinanta eukaryotiska celler. - Google Patents

Framstaellning av starkt exprimerande rekombinanta eukaryotiska celler. Download PDF

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Publication number
FI890946A
FI890946A FI890946A FI890946A FI890946A FI 890946 A FI890946 A FI 890946A FI 890946 A FI890946 A FI 890946A FI 890946 A FI890946 A FI 890946A FI 890946 A FI890946 A FI 890946A
Authority
FI
Finland
Prior art keywords
starkt
rekombinanta
exprimerande
eukaryotiska
celler
Prior art date
Application number
FI890946A
Other languages
English (en)
Other versions
FI108729B (fi
FI890946A0 (fi
Inventor
Gerd Zettlmeissl
Klaus-Dieter Langner
Manfred Wirth
Hansjoerg Hauser
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of FI890946A0 publication Critical patent/FI890946A0/fi
Publication of FI890946A publication Critical patent/FI890946A/fi
Application granted granted Critical
Publication of FI108729B publication Critical patent/FI108729B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121Serpins
    • C07K14/8128Antithrombin III
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI890946A 1988-03-02 1989-02-28 Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja FI108729B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3806617 1988-03-02
DE3806617A DE3806617A1 (de) 1988-03-02 1988-03-02 Erzeugung hochexprimierender, rekombinanter, eukaryotischer zellen

Publications (3)

Publication Number Publication Date
FI890946A0 FI890946A0 (fi) 1989-02-28
FI890946A true FI890946A (fi) 1989-09-03
FI108729B FI108729B (fi) 2002-03-15

Family

ID=6348554

Family Applications (1)

Application Number Title Priority Date Filing Date
FI890946A FI108729B (fi) 1988-03-02 1989-02-28 Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja

Country Status (10)

Country Link
EP (1) EP0330977A3 (fi)
JP (1) JPH0223873A (fi)
KR (1) KR0136909B1 (fi)
AU (1) AU617438B2 (fi)
CA (1) CA1339207C (fi)
DE (1) DE3806617A1 (fi)
DK (1) DK175625B1 (fi)
FI (1) FI108729B (fi)
PT (1) PT89880B (fi)
YU (1) YU44789A (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2090473A1 (en) * 1990-08-29 1992-03-01 Robert M. Kay Homologous recombinatin in mammalian cells
DE4037837A1 (de) * 1990-11-28 1992-06-04 Behringwerke Ag Zellfreie rezeptorbindungsteste, ihre herstellung und verwendung
DE4322330A1 (de) 1992-08-31 1994-03-03 Behringwerke Ag Verwendung des IL-4-Rezeptors zur Therapie, Prophylaxe und Diagnose von allergischen, viralen, parasitären und bakteriellen Erkrankungen sowie von Pilzinfektionen
DE4228839A1 (de) 1992-08-29 1994-03-03 Behringwerke Ag Verfahren zum Nachweis und zur Bestimmung von Mediatoren
US8765370B2 (en) * 2009-06-11 2014-07-01 Scinopharm Taiwan, Ltd Inhibition-based high-throughput screen strategy for cell clones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002708A1 (en) * 1985-10-24 1987-05-07 Siska Diagnostics, Inc. Lanthanide chelate-tagged nucleic acid probes
WO1987002707A1 (en) * 1985-11-05 1987-05-07 Genetics Institute, Inc. Multiply-amplifiable vectors for high level expression of exogenous dna

Also Published As

Publication number Publication date
AU617438B2 (en) 1991-11-28
DE3806617A1 (de) 1989-09-14
JPH0223873A (ja) 1990-01-26
KR0136909B1 (ko) 1998-04-25
EP0330977A3 (de) 1991-01-23
KR890014733A (ko) 1989-10-25
EP0330977A2 (de) 1989-09-06
DK99289D0 (da) 1989-03-01
FI108729B (fi) 2002-03-15
FI890946A0 (fi) 1989-02-28
CA1339207C (en) 1997-08-05
AU3085889A (en) 1989-09-07
PT89880A (pt) 1989-11-10
DK175625B1 (da) 2004-12-27
PT89880B (pt) 1994-05-31
YU44789A (en) 1990-06-30
DK99289A (da) 1989-09-03

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: BEHRINGWERKE AKTIENGESELLSCHAFT

MA Patent expired