FI890946A - Framstaellning av starkt exprimerande rekombinanta eukaryotiska celler. - Google Patents

Framstaellning av starkt exprimerande rekombinanta eukaryotiska celler. Download PDF

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Publication number
FI890946A
FI890946A FI890946A FI890946A FI890946A FI 890946 A FI890946 A FI 890946A FI 890946 A FI890946 A FI 890946A FI 890946 A FI890946 A FI 890946A FI 890946 A FI890946 A FI 890946A
Authority
FI
Finland
Prior art keywords
starkt
rekombinanta
exprimerande
eukaryotiska
celler
Prior art date
Application number
FI890946A
Other languages
English (en)
Other versions
FI890946A0 (fi
FI108729B (fi
Inventor
Gerd Zettlmeissl
Klaus-Dieter Langner
Manfred Wirth
Hansjoerg Hauser
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of FI890946A0 publication Critical patent/FI890946A0/fi
Publication of FI890946A publication Critical patent/FI890946A/fi
Application granted granted Critical
Publication of FI108729B publication Critical patent/FI108729B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI890946A 1988-03-02 1989-02-28 Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja FI108729B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3806617 1988-03-02
DE3806617A DE3806617A1 (de) 1988-03-02 1988-03-02 Erzeugung hochexprimierender, rekombinanter, eukaryotischer zellen

Publications (3)

Publication Number Publication Date
FI890946A0 FI890946A0 (fi) 1989-02-28
FI890946A true FI890946A (fi) 1989-09-03
FI108729B FI108729B (fi) 2002-03-15

Family

ID=6348554

Family Applications (1)

Application Number Title Priority Date Filing Date
FI890946A FI108729B (fi) 1988-03-02 1989-02-28 Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja

Country Status (10)

Country Link
EP (1) EP0330977A3 (fi)
JP (1) JPH0223873A (fi)
KR (1) KR0136909B1 (fi)
AU (1) AU617438B2 (fi)
CA (1) CA1339207C (fi)
DE (1) DE3806617A1 (fi)
DK (1) DK175625B1 (fi)
FI (1) FI108729B (fi)
PT (1) PT89880B (fi)
YU (1) YU44789A (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612205A (en) * 1990-08-29 1997-03-18 Genpharm International, Incorporated Homologous recombination in mammalian cells
DE4037837A1 (de) * 1990-11-28 1992-06-04 Behringwerke Ag Zellfreie rezeptorbindungsteste, ihre herstellung und verwendung
DE4322330A1 (de) 1992-08-31 1994-03-03 Behringwerke Ag Verwendung des IL-4-Rezeptors zur Therapie, Prophylaxe und Diagnose von allergischen, viralen, parasitären und bakteriellen Erkrankungen sowie von Pilzinfektionen
DE4228839A1 (de) 1992-08-29 1994-03-03 Behringwerke Ag Verfahren zum Nachweis und zur Bestimmung von Mediatoren
US8765370B2 (en) * 2009-06-11 2014-07-01 Scinopharm Taiwan, Ltd Inhibition-based high-throughput screen strategy for cell clones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244471A4 (en) * 1985-10-24 1988-01-28 Siska Diagnostics Inc NUCLEIC ACID SAMPLES MARKED WITH LANTHANIDE CHELATE.
WO1987002707A1 (en) * 1985-11-05 1987-05-07 Genetics Institute, Inc. Multiply-amplifiable vectors for high level expression of exogenous dna

Also Published As

Publication number Publication date
AU3085889A (en) 1989-09-07
FI890946A0 (fi) 1989-02-28
KR0136909B1 (ko) 1998-04-25
DK175625B1 (da) 2004-12-27
DK99289A (da) 1989-09-03
PT89880A (pt) 1989-11-10
EP0330977A3 (de) 1991-01-23
AU617438B2 (en) 1991-11-28
JPH0223873A (ja) 1990-01-26
EP0330977A2 (de) 1989-09-06
DK99289D0 (da) 1989-03-01
PT89880B (pt) 1994-05-31
FI108729B (fi) 2002-03-15
DE3806617A1 (de) 1989-09-14
KR890014733A (ko) 1989-10-25
CA1339207C (en) 1997-08-05
YU44789A (en) 1990-06-30

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: BEHRINGWERKE AKTIENGESELLSCHAFT

MA Patent expired