FI890419A - Foerfarande foer framstaellning av terapeutiskt anvaendbara pyrazin-, pyrimidin- och pyridazinderivat. - Google Patents
Foerfarande foer framstaellning av terapeutiskt anvaendbara pyrazin-, pyrimidin- och pyridazinderivat. Download PDFInfo
- Publication number
- FI890419A FI890419A FI890419A FI890419A FI890419A FI 890419 A FI890419 A FI 890419A FI 890419 A FI890419 A FI 890419A FI 890419 A FI890419 A FI 890419A FI 890419 A FI890419 A FI 890419A
- Authority
- FI
- Finland
- Prior art keywords
- pyridazinderivat
- pyrazin
- pyrimidin
- och
- foerfarande foer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888802101A GB8802101D0 (en) | 1988-01-30 | 1988-01-30 | Therapeutic agents |
| GB888815225A GB8815225D0 (en) | 1988-06-27 | 1988-06-27 | Therapeutic agents |
| GB888817812A GB8817812D0 (en) | 1988-07-26 | 1988-07-26 | Therapeutic agents |
| GB888821088A GB8821088D0 (en) | 1988-09-08 | 1988-09-08 | Therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI890419A0 FI890419A0 (fi) | 1989-01-27 |
| FI890419A true FI890419A (fi) | 1989-07-31 |
Family
ID=27450036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI890419A FI890419A (fi) | 1988-01-30 | 1989-01-27 | Foerfarande foer framstaellning av terapeutiskt anvaendbara pyrazin-, pyrimidin- och pyridazinderivat. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0327155A3 (fi) |
| JP (1) | JPH02111768A (fi) |
| KR (1) | KR890011860A (fi) |
| AU (1) | AU622141B2 (fi) |
| DK (1) | DK35389A (fi) |
| FI (1) | FI890419A (fi) |
| IL (1) | IL89034A0 (fi) |
| NO (1) | NO890364L (fi) |
| NZ (1) | NZ227684A (fi) |
| PT (1) | PT89523B (fi) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8808433D0 (en) * | 1988-04-11 | 1988-05-11 | Merck Sharp & Dohme | Therapeutic agents |
| US5177084A (en) * | 1989-08-08 | 1993-01-05 | Merck Sharp & Dohme Ltd. | Therapeutic use of substituted benzenes, formulations thereof and novel substituted benzenes |
| GB8918060D0 (en) * | 1989-08-08 | 1989-09-20 | Merck Sharp & Dohme | Therapeutic agents |
| EP0413545B1 (en) * | 1989-08-16 | 1997-05-14 | Beecham Group Plc | Azabicyclic compounds |
| GB9005737D0 (en) * | 1990-03-14 | 1990-05-09 | Beecham Group Plc | Novel compounds |
| DK72790D0 (da) * | 1990-03-21 | 1990-03-21 | Ferrosan As | Heterocycliske forbindelser, deres fremstilling og anvendelse |
| GB9017353D0 (en) * | 1990-08-08 | 1990-09-19 | Merck Sharp & Dohme | Chemical process |
| CA2050264A1 (en) * | 1990-08-30 | 1992-03-01 | Raymond Baker | Substituted pyrazine and its salts, compositions containing them and their use in medicine |
| EP0492902A1 (en) * | 1990-12-21 | 1992-07-01 | MERCK SHARP & DOHME LTD. | Substituted pyridine derivatives for use in the treatment of glaucoma |
| EP0492903A1 (en) * | 1990-12-21 | 1992-07-01 | MERCK SHARP & DOHME LTD. | Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma |
| GB9201749D0 (en) * | 1992-01-28 | 1992-03-11 | Smithkline Beecham Plc | Medicaments |
| AU672644B2 (en) * | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
| AU672052B2 (en) * | 1992-12-23 | 1996-09-19 | Neurosearch A/S | Antidepressant and antiparkinsonian compounds |
| AU671163B2 (en) * | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
| CA2238555A1 (en) * | 1995-11-29 | 1997-06-05 | Charles Howard Mitch | Heterocyclic compounds and their use |
| US5889019A (en) * | 1995-11-29 | 1999-03-30 | Eli Lilly And Company | Heterocyclic compounds and their use |
| US5834458A (en) * | 1996-10-09 | 1998-11-10 | Eli Lilly And Company | Heterocyclic compounds and their use |
| US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
| CA2287223A1 (en) * | 1997-04-26 | 1998-11-05 | Tomohiro Toyoda | 2-azabicyclo compounds |
| EE200200453A (et) * | 2000-02-16 | 2003-12-15 | Neurogen Corporation | Asendatud arüülpürasiinid |
| US20060025468A1 (en) * | 2004-07-29 | 2006-02-02 | Whitten Jeffrey P | Chiral pyrrolidine derivatives, and methods for preparing compounds thereof |
| JP2007032031A (ja) * | 2005-07-25 | 2007-02-08 | Sanyo Industries Ltd | 持出し手摺構造及びその取付け方法 |
| BR122020005073A2 (pt) | 2017-08-04 | 2020-10-13 | Skyhawk Therapeutics, Inc. | Composto, composição farmacêutica e uso do composto |
| JP2022519636A (ja) * | 2019-02-04 | 2022-03-24 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| CN114007611A (zh) * | 2019-02-04 | 2022-02-01 | 斯基霍克疗法公司 | 用于调节剪接的方法和组合物 |
| KR20210135241A (ko) | 2019-02-05 | 2021-11-12 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
| KR20210135507A (ko) | 2019-02-06 | 2021-11-15 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4911710B1 (fi) * | 1970-12-30 | 1974-03-19 | ||
| JPS4911710A (fi) * | 1972-05-15 | 1974-02-01 | ||
| CA1244028A (en) * | 1983-04-14 | 1988-11-01 | Hans Maag | Pyrimidine derivatives |
| ZA842595B (en) * | 1983-04-14 | 1985-11-27 | Hoffmann La Roche | Pyrimidine derivatives |
| NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
| ATE133415T1 (de) * | 1987-04-15 | 1996-02-15 | Beecham Group Plc | Am brückenkopf substituierte azabicyclenderivate |
| CA2000041A1 (en) * | 1988-10-13 | 1990-04-13 | Barry S. Orlek | Compounds |
-
1989
- 1989-01-20 NZ NZ227684A patent/NZ227684A/en unknown
- 1989-01-23 EP EP19890200147 patent/EP0327155A3/en not_active Withdrawn
- 1989-01-23 IL IL89034A patent/IL89034A0/xx unknown
- 1989-01-25 PT PT89523A patent/PT89523B/pt active IP Right Grant
- 1989-01-27 DK DK035389A patent/DK35389A/da not_active Application Discontinuation
- 1989-01-27 AU AU28834/89A patent/AU622141B2/en not_active Expired - Fee Related
- 1989-01-27 FI FI890419A patent/FI890419A/fi not_active Application Discontinuation
- 1989-01-27 NO NO89890364A patent/NO890364L/no unknown
- 1989-01-27 KR KR1019890000869A patent/KR890011860A/ko not_active Application Discontinuation
- 1989-01-30 JP JP1017823A patent/JPH02111768A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR890011860A (ko) | 1989-08-23 |
| AU2883489A (en) | 1989-08-03 |
| JPH02111768A (ja) | 1990-04-24 |
| FI890419A0 (fi) | 1989-01-27 |
| DK35389A (da) | 1989-07-31 |
| NO890364L (no) | 1989-07-31 |
| IL89034A0 (en) | 1989-08-15 |
| NZ227684A (en) | 1991-07-26 |
| PT89523A (pt) | 1989-10-04 |
| EP0327155A2 (en) | 1989-08-09 |
| AU622141B2 (en) | 1992-04-02 |
| PT89523B (pt) | 1994-02-28 |
| NO890364D0 (no) | 1989-01-27 |
| DK35389D0 (da) | 1989-01-27 |
| EP0327155A3 (en) | 1992-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: MERCK SHARP & DOHME LIMITED |