FI885424A0 - Diacylderivat av 4-(trialkylbensyl) -piperazinylfoereningar. - Google Patents

Diacylderivat av 4-(trialkylbensyl) -piperazinylfoereningar.

Info

Publication number
FI885424A0
FI885424A0 FI885424A FI885424A FI885424A0 FI 885424 A0 FI885424 A0 FI 885424A0 FI 885424 A FI885424 A FI 885424A FI 885424 A FI885424 A FI 885424A FI 885424 A0 FI885424 A0 FI 885424A0
Authority
FI
Finland
Prior art keywords
trialkylbensyl
piperazinylfoereningar
diacylderivat
Prior art date
Application number
FI885424A
Other languages
English (en)
Other versions
FI87567B (fi
FI885424A (fi
FI87567C (fi
Inventor
Peter Traxler
Klaus Mueller
Wilhelm Kump
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI885424A0 publication Critical patent/FI885424A0/fi
Publication of FI885424A publication Critical patent/FI885424A/fi
Publication of FI87567B publication Critical patent/FI87567B/fi
Application granted granted Critical
Publication of FI87567C publication Critical patent/FI87567C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI885424A 1987-09-25 1988-11-23 Foerfarande foer framstaellning av terapeutiskt verkande 8-o,n- och 8-o,21-diacyl-4-(trialkylbensyl)-piperazin-1-ylderivat av rifamycin s FI87567C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CH1987/000123 WO1989002894A1 (en) 1987-09-25 1987-09-25 Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds
CH8700123 1987-09-25

Publications (4)

Publication Number Publication Date
FI885424A0 true FI885424A0 (fi) 1988-11-23
FI885424A FI885424A (fi) 1989-03-26
FI87567B FI87567B (fi) 1992-10-15
FI87567C FI87567C (fi) 1993-01-25

Family

ID=4543936

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885424A FI87567C (fi) 1987-09-25 1988-11-23 Foerfarande foer framstaellning av terapeutiskt verkande 8-o,n- och 8-o,21-diacyl-4-(trialkylbensyl)-piperazin-1-ylderivat av rifamycin s

Country Status (8)

Country Link
US (1) US4916126A (fi)
JP (1) JPH02501301A (fi)
KR (1) KR890701591A (fi)
AU (1) AU621811B2 (fi)
DK (1) DK81089A (fi)
FI (1) FI87567C (fi)
NO (1) NO167204C (fi)
WO (1) WO1989002894A1 (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314624A1 (de) * 1987-10-27 1989-05-03 Ciba-Geigy Ag Substituierte Azacyclohexyl-Derivate
GB8725118D0 (en) * 1987-10-27 1987-12-02 Ciba Geigy Ag Rifamycin derivatives
GB8816620D0 (en) * 1988-07-13 1988-08-17 Lepetit Spa Rifapentine hydrohalides
US5180718A (en) * 1989-03-02 1993-01-19 Ciba-Geigy Corporation Acyl derivatives of oxazolorifamycins
CA2214072C (en) * 1996-08-29 2006-11-14 Eli Lilly And Company Benzo [b] thiophene compounds, intermediates, processes, compositions, and methods
CA2214070C (en) * 1996-08-29 2006-03-14 Eli Lilly And Company Dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods
IN183239B (fi) * 1996-09-25 1999-10-09 Lilly Co Eli
CA2214931A1 (en) * 1996-09-26 1998-03-26 Henry Uhlman Bryant Tetrahydrobenzo-a-fluorene compounds and method of use
CA2214922A1 (en) * 1996-09-27 1998-03-27 Eli Lilly And Company Benzothiophene compounds, compositions, and methods
CA2214872C (en) * 1996-10-24 2002-01-22 Eli Lilly And Company Benzothiophene compounds, compositions and methods
CA2215647A1 (en) * 1996-10-24 1998-04-24 Eli Lilly And Company Naphthyl compounds, compositions, and methods
CA2216592C (en) * 1996-10-24 2006-07-18 Brian Stephen Muehl Benzothiophene compounds, intermediates, compositions, and methods
WO1998048806A1 (en) * 1997-04-25 1998-11-05 Eli Lilly And Company Indene compounds having activity as serms
JP2001524114A (ja) * 1997-04-30 2001-11-27 イーライ・リリー・アンド・カンパニー ベンゾ［ｂ］チオフェン類の製造における中間体および方法
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
WO2004054548A1 (en) * 2002-12-12 2004-07-01 Activbiotics,Inc. Method and reagents for treating or preventing atherosclerosis and diseases associated therewith

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR208F (fi) * 1964-07-31
US4261891A (en) * 1965-08-24 1981-04-14 Ciba-Geigy Corporation Antibiotically active rifamycin derivatives
US4005077A (en) * 1965-08-24 1977-01-25 Ciba-Geigy Corporation Antibiotically active compounds
CH484898A (de) * 1967-05-29 1970-01-31 Ciba Geigy Verfahren zur Herstellung von 3-Formylrifamycin SV
CH507977A (de) * 1967-06-16 1971-05-31 Ciba Geigy Ag Verfahren zur Herstellung von 3-Formylrifamycin-SV
IT1046627B (it) * 1970-06-01 1980-07-31 Lepetit Spa Composizioni antivirali contenenti derivati della rifaumicina sv
GB1486118A (en) * 1975-03-05 1977-09-21 Lepetit Spa Rifamycin derivatives
GB1478563A (en) * 1975-03-05 1977-07-06 Lepetit Spa Rifamycin derivatives
GR64108B (en) * 1977-04-15 1980-01-24 Dso Pharmachim Method for the preparation of azomethine-derivatives of rifamycin s.v
GB8308166D0 (en) * 1983-03-24 1983-05-05 Erba Farmitalia Preparation of azinomethyl-rifamycins
GB8318072D0 (en) * 1983-07-04 1983-08-03 Lepetit Spa Water-soluble rifampicin derivatives
US4551450A (en) * 1984-08-27 1985-11-05 Ciba-Geigy Corporation Rifamycin hydrazones, pharmaceutical compositions containing them and their use
US4681938A (en) * 1984-08-27 1987-07-21 Ciba-Geigy Corporation Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis
US4631290A (en) * 1985-08-29 1986-12-23 American Home Products Corporation Method of treating hepatitis
WO1987002361A1 (en) * 1985-10-18 1987-04-23 Ciba-Geigy Ag Substituted 4-benzyl-piperazinyl compounds
AU582799B2 (en) * 1985-10-18 1989-04-13 Ciba-Geigy Ag Substituted 4-benzyl-piperazinyl compounds
US4774237A (en) * 1986-02-14 1988-09-27 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Expellants of phytopathogenic microbes

Also Published As

Publication number Publication date
DK81089D0 (da) 1989-02-22
WO1989002894A1 (en) 1989-04-06
AU621811B2 (en) 1992-03-26
NO167204B (no) 1991-07-08
NO885806D0 (no) 1988-12-29
FI87567B (fi) 1992-10-15
NO885806L (no) 1989-03-06
NO167204C (no) 1991-10-23
DK81089A (da) 1989-04-06
US4916126A (en) 1990-04-10
KR890701591A (ko) 1989-12-21
FI885424A (fi) 1989-03-26
JPH02501301A (ja) 1990-05-10
FI87567C (fi) 1993-01-25
AU7917687A (en) 1989-04-18

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: CIBA-GEIGY AG