FI882019A - Monoclonal antibodies for selective, immunological determination of intact procollagen peptide (type III) and procollagen (type III) from body fluids - Google Patents

Monoclonal antibodies for selective, immunological determination of intact procollagen peptide (type III) and procollagen (type III) from body fluids Download PDF

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Publication number
FI882019A
FI882019A FI882019A FI882019A FI882019A FI 882019 A FI882019 A FI 882019A FI 882019 A FI882019 A FI 882019A FI 882019 A FI882019 A FI 882019A FI 882019 A FI882019 A FI 882019A
Authority
FI
Finland
Prior art keywords
type iii
procollagen
body fluids
selective
monoclonal antibodies
Prior art date
Application number
FI882019A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI96433B (en
FI96433C (en
FI882019A0 (en
Inventor
Dietrich Brocks
Juergen Puenter
Helmut Strecker
Rupert Timpl
Original Assignee
Hoechst Ag
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Max Planck Gesellschaft filed Critical Hoechst Ag
Publication of FI882019A0 publication Critical patent/FI882019A0/en
Publication of FI882019A publication Critical patent/FI882019A/en
Publication of FI96433B publication Critical patent/FI96433B/en
Application granted granted Critical
Publication of FI96433C publication Critical patent/FI96433C/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Pressure Welding/Diffusion-Bonding (AREA)

Abstract

Procollagen peptide can be determined with great accuracy in body fluids with the aid of a monoclonal antibody which is specifically directed against an epitope of the amino-terminal procollagen peptide (type III) which is not present in Col 1.
FI882019A 1987-05-02 1988-04-29 Monoclonal antibodies for selective, immunological determination of intact procollagen peptide (type III) and procollagen (type III) from body fluids FI96433C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3714633 1987-05-02
DE3714633 1987-05-02

Publications (4)

Publication Number Publication Date
FI882019A0 FI882019A0 (en) 1988-04-29
FI882019A true FI882019A (en) 1988-11-03
FI96433B FI96433B (en) 1996-03-15
FI96433C FI96433C (en) 1996-06-25

Family

ID=6326685

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882019A FI96433C (en) 1987-05-02 1988-04-29 Monoclonal antibodies for selective, immunological determination of intact procollagen peptide (type III) and procollagen (type III) from body fluids

Country Status (10)

Country Link
EP (1) EP0289930B1 (en)
JP (1) JPH07110879B2 (en)
AT (1) ATE89862T1 (en)
DE (1) DE3881275D1 (en)
DK (1) DK169583B1 (en)
ES (1) ES2056850T3 (en)
FI (1) FI96433C (en)
IE (1) IE63371B1 (en)
NO (1) NO173104C (en)
PT (1) PT87376B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679583A (en) * 1987-05-02 1997-10-21 Hoechst Aktiengesellschaft Monoclonal antibodies for the selective immunological determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids
GB2208865B (en) * 1987-08-19 1991-12-11 Farmos Group Ltd Purified propeptide of procollagen type iii, antibody to the propeptide and assay method using the antibody.
US6010862A (en) * 1987-11-06 2000-01-04 Washington Research Foundation Methods of detecting collagen type III degradation in vivo
AU4362399A (en) * 1998-05-28 1999-12-13 Bayer Aktiengesellschaft Monoclonal antibody and assay for detecting piiinp
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209149A1 (en) * 1982-03-13 1983-10-06 Hoechst Ag METHOD FOR THE COMMON IMMUNOLOGICAL DETERMINATION OF PROCOLLAGEN PEPTIDE (TYPE III) AND PROCOLLAGEN PEPTIDE COL 1 (TYPE III) AND METHOD FOR THE PRODUCTION OF ANTI-PROCOLLAGEN PEPTIDE COL 1 (TYPE III) SERUM

Also Published As

Publication number Publication date
EP0289930B1 (en) 1993-05-26
FI96433B (en) 1996-03-15
PT87376A (en) 1989-05-31
EP0289930A2 (en) 1988-11-09
FI96433C (en) 1996-06-25
ATE89862T1 (en) 1993-06-15
ES2056850T3 (en) 1994-10-16
NO173104C (en) 1993-10-27
FI882019A0 (en) 1988-04-29
NO881905D0 (en) 1988-04-29
IE881290L (en) 1988-11-02
JPS63296695A (en) 1988-12-02
JPH07110879B2 (en) 1995-11-29
DK232888D0 (en) 1988-04-28
DK169583B1 (en) 1994-12-12
PT87376B (en) 1992-08-31
NO881905L (en) 1988-11-03
DK232888A (en) 1988-11-03
IE63371B1 (en) 1995-04-19
DE3881275D1 (en) 1993-07-01
EP0289930A3 (en) 1991-06-12
NO173104B (en) 1993-07-19

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed

Owner name: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENS

Owner name: HOECHST AKTIENGESELLSCHAFT