FI882018A - Method for selective immunologic determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids and agents for carrying out this - Google Patents

Method for selective immunologic determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids and agents for carrying out this Download PDF

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Publication number
FI882018A
FI882018A FI882018A FI882018A FI882018A FI 882018 A FI882018 A FI 882018A FI 882018 A FI882018 A FI 882018A FI 882018 A FI882018 A FI 882018A FI 882018 A FI882018 A FI 882018A
Authority
FI
Finland
Prior art keywords
type iii
procollagen
body fluids
selective
agents
Prior art date
Application number
FI882018A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI95579B (en
FI882018A0 (en
FI95579C (en
Inventor
Dietrich Brocks
Rubert Timpl
Original Assignee
Hoechst Ag
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Max Planck Gesellschaft filed Critical Hoechst Ag
Publication of FI882018A0 publication Critical patent/FI882018A0/en
Publication of FI882018A publication Critical patent/FI882018A/en
Publication of FI95579B publication Critical patent/FI95579B/en
Application granted granted Critical
Publication of FI95579C publication Critical patent/FI95579C/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lifting Devices For Agricultural Implements (AREA)
  • Tires In General (AREA)
  • Agricultural Machines (AREA)

Abstract

It is possible by immunising animals with a peptide of the sequence I-C-E-S-C-P-T-G-G-Q-N-Y-S-P bound to an immunogenic protein to raise antibodies which can be used to determine procollagen peptide (type III) and procollagen type III selectively in body fluids.
FI882018A 1987-05-02 1988-04-29 Method for selective immunologic determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids and agents for carrying out this FI95579C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873714634 DE3714634A1 (en) 1987-05-02 1987-05-02 METHOD FOR SELECTIVE IMMUNOLOGICAL DETERMINATION OF INTACT PROCOLLAGEN PEPTIDE (TYPE III) AND PROCOLLAGEN (TYPE III) IN BODY LIQUIDS AND MEANS TO IMPLEMENT IT
DE3714634 1987-05-02

Publications (4)

Publication Number Publication Date
FI882018A0 FI882018A0 (en) 1988-04-29
FI882018A true FI882018A (en) 1988-11-03
FI95579B FI95579B (en) 1995-11-15
FI95579C FI95579C (en) 1996-02-26

Family

ID=6326686

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882018A FI95579C (en) 1987-05-02 1988-04-29 Method for selective immunologic determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids and agents for carrying out this

Country Status (10)

Country Link
EP (1) EP0298210B1 (en)
JP (1) JPH0780913B2 (en)
AT (1) ATE98377T1 (en)
DE (2) DE3714634A1 (en)
DK (1) DK168872B1 (en)
ES (1) ES2061545T3 (en)
FI (1) FI95579C (en)
IE (1) IE63385B1 (en)
NO (1) NO175639C (en)
PT (1) PT87375B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010862A (en) * 1987-11-06 2000-01-04 Washington Research Foundation Methods of detecting collagen type III degradation in vivo
DE4225038C2 (en) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Production and use of antibodies against collagen
CA2167496A1 (en) * 1993-07-28 1995-02-09 Werner Naser Immunoassay for the detection of collagen or collagen fragments
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
EP0787301B1 (en) 1994-10-17 2001-02-14 Osteometer Biotech AS Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
WO1998026286A2 (en) 1996-12-09 1998-06-18 Osteometer Biotech A/S Sandwich assays for collagen type i fragments
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
DE69915059T2 (en) * 1998-05-28 2004-08-26 Bayer Healthcare Ag MONOCLONAL ANTIBODY AND ASSAY FOR DETERMINING N-TERMINAL PROCOLLAGEN PROPEPTIDE TYPE III (PIIINP)
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816841A1 (en) * 1978-04-18 1979-10-31 Max Planck Gesellschaft RADIOIMMUNOLOGICAL DETERMINATION OF PROCOLLAGEN (TYPE III) AND PROCOLLAGEN PEPTIDE (TYPE III)
DE3209149A1 (en) * 1982-03-13 1983-10-06 Hoechst Ag METHOD FOR THE COMMON IMMUNOLOGICAL DETERMINATION OF PROCOLLAGEN PEPTIDE (TYPE III) AND PROCOLLAGEN PEPTIDE COL 1 (TYPE III) AND METHOD FOR THE PRODUCTION OF ANTI-PROCOLLAGEN PEPTIDE COL 1 (TYPE III) SERUM

Also Published As

Publication number Publication date
EP0298210A2 (en) 1989-01-11
ATE98377T1 (en) 1993-12-15
JPH0780913B2 (en) 1995-08-30
DK168872B1 (en) 1994-06-27
FI95579B (en) 1995-11-15
IE881289L (en) 1988-11-02
JPS63292061A (en) 1988-11-29
NO175639B (en) 1994-08-01
EP0298210B1 (en) 1993-12-08
PT87375A (en) 1989-05-31
DE3886109D1 (en) 1994-01-20
NO881904L (en) 1988-11-03
FI882018A0 (en) 1988-04-29
ES2061545T3 (en) 1994-12-16
DK232988A (en) 1988-11-03
NO881904D0 (en) 1988-04-29
EP0298210A3 (en) 1991-05-15
PT87375B (en) 1992-08-31
FI95579C (en) 1996-02-26
DE3714634A1 (en) 1988-11-17
NO175639C (en) 1994-11-09
IE63385B1 (en) 1995-04-19
DK232988D0 (en) 1988-04-28

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BB Publication of examined application
MM Patent lapsed

Owner name: HOECHST AKTIENGESELLSCHAFT

Owner name: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENS