FI873365A - FOERFARANDE FOER FRAMSTAELLNING AV NYA FOSFO-FOERENINGAR. - Google Patents
FOERFARANDE FOER FRAMSTAELLNING AV NYA FOSFO-FOERENINGAR. Download PDFInfo
- Publication number
- FI873365A FI873365A FI873365A FI873365A FI873365A FI 873365 A FI873365 A FI 873365A FI 873365 A FI873365 A FI 873365A FI 873365 A FI873365 A FI 873365A FI 873365 A FI873365 A FI 873365A
- Authority
- FI
- Finland
- Prior art keywords
- group
- alkylamino
- denotes
- alkyl group
- unsaturated
- Prior art date
Links
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- -1 2-tert-butyloxycarbonylaminoethyl Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
The invention relates to cytostatically active compounds of the formula I <IMAGE> in which R denotes an unsaturated or saturated hydrocarbon radical having 12-14 C atoms, and which can additionally be substituted by halogen, X is an oxygen atom, NH or NR2, n denotes the integer 0-10, R1 is a C1-C8-alkyl group or R1 denotes a C2-C8-alkyl group which is unsaturated or substituted by halogen, amino, C1-C6-alkylamino, di-C1-C6 alkylamino, tri-C1-C6-alkylamino, hydroxyl, carboxyl, C3-C8- cycloalkyl or phenyl and in which formula R1 can additionally denote 2-tert-butyloxycarbonylaminoethyl, 2tert- butyloxycarbonylethyl, a 2,3-isopropylidenedioxypropyl-(1)- group, a 2,3-dibenzyloxypropyl-(1)-group, a 1,3- dibenzyloxypropyl-(2)-group or NC1-C6-alkylamino-C2-C6- alkyl, when X is an oxygen atom, and in which formula R1 can additionally denote a 2,3-dihydroxypropyl-(1)-group, where X is an NH group, and R2 denotes a 2,3-dihydroxypropyl-(1)- group, a C1-C8-alkyl group or a C2-C8-alkyl group which is unsaturated and/or substituted by halogen, amino, C1-C6 alkylamino, di-C1-C6-alkylamino, tri-C1-C6-alkylamino, hydroxyl, carboxyl, C3-C8-cycloalkyl or phenyl, and also to physiologically acceptable salts of these compounds and to a process for preparing them.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3542894 | 1985-12-04 | ||
DE3542894 | 1985-12-04 | ||
DE19863606633 DE3606633A1 (en) | 1986-02-28 | 1986-02-28 | Novel phospho compounds and medicaments containing them |
DE3606633 | 1986-02-28 | ||
PCT/EP1986/000707 WO1987003596A2 (en) | 1985-12-04 | 1986-12-04 | Novel phospho-compounds and medicaments containing these |
EP8600707 | 1986-12-04 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI873365A true FI873365A (en) | 1987-08-03 |
FI873365A0 FI873365A0 (en) | 1987-08-03 |
FI84832B FI84832B (en) | 1991-10-15 |
FI84832C FI84832C (en) | 1992-01-27 |
Family
ID=25838511
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI873365A FI84832C (en) | 1985-12-04 | 1987-08-03 | FOERFARANDE FOER FRAMSTAELLNING AV NYA FOSFO-FOERENINGAR. |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0224925A3 (en) |
JP (1) | JPS63502824A (en) |
DE (1) | DE3669161D1 (en) |
ES (1) | ES2018578B3 (en) |
FI (1) | FI84832C (en) |
HU (1) | HU203359B (en) |
IE (1) | IE59664B1 (en) |
PT (1) | PT83874B (en) |
WO (1) | WO1987003596A2 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0061872B1 (en) * | 1981-03-30 | 1985-08-07 | Takeda Chemical Industries, Ltd. | Ethyleneglycol derivatives, their production and use |
DE3307925A1 (en) * | 1983-03-05 | 1984-09-06 | A. Nattermann & Cie GmbH, 5000 Köln | NEW 0-ACYL-ALKANDIOL PHOSPHOLIPIDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
-
1986
- 1986-12-03 IE IE317586A patent/IE59664B1/en not_active IP Right Cessation
- 1986-12-04 ES ES87900102T patent/ES2018578B3/en not_active Expired - Lifetime
- 1986-12-04 JP JP62500471A patent/JPS63502824A/en active Pending
- 1986-12-04 HU HU87829A patent/HU203359B/en not_active IP Right Cessation
- 1986-12-04 EP EP86116861A patent/EP0224925A3/en active Pending
- 1986-12-04 DE DE8787900102T patent/DE3669161D1/en not_active Expired - Lifetime
- 1986-12-04 PT PT83874A patent/PT83874B/en not_active IP Right Cessation
- 1986-12-04 EP EP87900102A patent/EP0248858B1/en not_active Expired - Lifetime
- 1986-12-04 WO PCT/EP1986/000707 patent/WO1987003596A2/en active IP Right Grant
-
1987
- 1987-08-03 FI FI873365A patent/FI84832C/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE863175L (en) | 1987-06-04 |
EP0248858B1 (en) | 1990-02-28 |
EP0224925A3 (en) | 1987-10-21 |
PT83874B (en) | 1989-01-17 |
WO1987003596A2 (en) | 1987-06-18 |
HUT47298A (en) | 1989-02-28 |
ES2018578B3 (en) | 1991-04-16 |
EP0248858A1 (en) | 1987-12-16 |
HU203359B (en) | 1991-07-29 |
JPS63502824A (en) | 1988-10-20 |
FI84832C (en) | 1992-01-27 |
PT83874A (en) | 1987-01-01 |
DE3669161D1 (en) | 1990-04-05 |
WO1987003596A3 (en) | 1987-09-24 |
FI84832B (en) | 1991-10-15 |
FI873365A0 (en) | 1987-08-03 |
IE59664B1 (en) | 1994-03-09 |
EP0224925A2 (en) | 1987-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENS |