FI862801A - NYA KEMISKA FOERENINGAR. - Google Patents

NYA KEMISKA FOERENINGAR. Download PDF

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Publication number
FI862801A
FI862801A FI862801A FI862801A FI862801A FI 862801 A FI862801 A FI 862801A FI 862801 A FI862801 A FI 862801A FI 862801 A FI862801 A FI 862801A FI 862801 A FI862801 A FI 862801A
Authority
FI
Finland
Prior art keywords
kemiska
foereningar
nya
nya kemiska
kemiska foereningar
Prior art date
Application number
FI862801A
Other languages
Finnish (fi)
Other versions
FI862801A0 (en
FI84474C (en
FI84474B (en
Inventor
Albert A Carr
Norbert L Wiech
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of FI862801A0 publication Critical patent/FI862801A0/en
Publication of FI862801A publication Critical patent/FI862801A/en
Application granted granted Critical
Publication of FI84474B publication Critical patent/FI84474B/en
Publication of FI84474C publication Critical patent/FI84474C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI862801A 1985-07-02 1986-07-01 Process for the preparation of therapeutically active -phenyl- (N-phenylalkyl-4-piperidyl) methanol derivatives FI84474C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75141985A 1985-07-02 1985-07-02
US75141985 1985-07-02

Publications (4)

Publication Number Publication Date
FI862801A0 FI862801A0 (en) 1986-07-01
FI862801A true FI862801A (en) 1987-01-03
FI84474B FI84474B (en) 1991-08-30
FI84474C FI84474C (en) 1991-12-10

Family

ID=25021900

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862801A FI84474C (en) 1985-07-02 1986-07-01 Process for the preparation of therapeutically active -phenyl- (N-phenylalkyl-4-piperidyl) methanol derivatives

Country Status (21)

Country Link
EP (1) EP0208235B1 (en)
JP (1) JPH0655720B2 (en)
KR (1) KR900001184B1 (en)
CN (1) CN1023895C (en)
AR (2) AR241904A1 (en)
AT (1) ATE49403T1 (en)
AU (1) AU590582B2 (en)
CA (1) CA1280421C (en)
DE (1) DE3668167D1 (en)
DK (1) DK174153B1 (en)
ES (1) ES2000299A6 (en)
FI (1) FI84474C (en)
GR (1) GR861699B (en)
HU (1) HU196058B (en)
IE (1) IE58460B1 (en)
IL (1) IL79266A (en)
NO (1) NO167384C (en)
NZ (1) NZ216689A (en)
PH (1) PH22141A (en)
PT (1) PT82890B (en)
ZA (1) ZA864772B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910006138B1 (en) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 Cyclic amine derivatives
ZA888572B (en) * 1987-11-23 1989-08-30 Merrell Dow Pharma Treatment of fibromyalgia
JPH02138214A (en) * 1987-12-10 1990-05-28 Merrell Dow Pharmaceut Inc Therapeutic method of anxiety
US5093341A (en) * 1987-12-17 1992-03-03 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine derivatives useful as antithrombolytic agents
ATE102482T1 (en) * 1988-01-21 1994-03-15 Merrell Dow Pharma USE OF 1,4-DISUBSTITUTED PIPERIDINYL COMPOUNDS IN THE MANUFACTURE OF A MEDICATION FOR THE TREATMENT OF INSOMNIA.
ZA891901B (en) * 1988-03-17 1989-11-29 Merrell Dow Pharma Method for the treatment of the extrapyramidal side effects associated with neuroleptic therapy
JP2969359B2 (en) * 1989-01-13 1999-11-02 武田薬品工業株式会社 Cyclic amine compounds
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
ZA9010081B (en) * 1989-12-20 1991-10-30 Merrell Dow Pharma Method for the treatment of glaucoma
JP2758050B2 (en) * 1989-12-27 1998-05-25 株式会社トクヤマ Chemical solution for soil stabilization and its injection method
AU652759B2 (en) * 1990-06-01 1994-09-08 Aventisub Ii Inc. (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)- 4-piperidinemethanol
US6004980A (en) * 1990-06-01 1999-12-21 Merrell Pharmaceuticals, Inc. (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
JPH07111050B2 (en) * 1990-12-12 1995-11-29 株式会社親和テクノ Ground injection method using cement grout
FR2672286B1 (en) * 1991-01-31 1994-11-18 Synthelabo DERIVATIVES OF 1- (4-CHLOROPHENYL) -2- [4- (PHENYLMETHYL) PIPERIDIN-1-YL] ETHANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
ZA929008B (en) * 1991-12-13 1993-05-21 Bristol Myers Squibb Co Piperazinyl- and piperidinyl-cyclohexanols.
WO1994000432A1 (en) * 1992-06-30 1994-01-06 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Anorectic epinephrine derivatives
FR2696741B1 (en) * 1992-10-12 1994-11-25 Synthelabo 1- (4-Chlorophenyl) -2- [4 - [(4-fluorophenyl) methyl] piperidin-1-yl] ethanol derivatives, their preparation and their therapeutic use.
CA2108245A1 (en) * 1992-11-04 1994-05-05 Gary J. Grover Method for treating myocardial ischemia employing serotonin receptor antagonists
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
WO1997022583A1 (en) * 1995-12-20 1997-06-26 Eckhart Pein Novel 1-phenylalkyl/alkylene-4-(.alpha.-hydroxydiphenylmethyl)-piperidine derivatives and their use as serotonin antagonists
US6028083A (en) * 1997-07-25 2000-02-22 Hoechst Marion Roussel, Inc. Esters of (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol
US6713627B2 (en) 1998-03-13 2004-03-30 Aventis Pharmaceuticals Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
TWI249526B (en) * 1998-03-13 2006-02-21 Aventis Pharma Inc Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
SE9801516D0 (en) * 1998-04-30 1998-04-30 Maria Carlsson M100907 / 4-Piperidine methanol derivatives for autism
DE19934432A1 (en) 1999-07-22 2001-02-01 Merck Patent Gmbh Indole derivatives
DE19939756A1 (en) * 1999-08-21 2001-02-22 Merck Patent Gmbh New 1-(1-ethyl-piperidin-4-yl)-1-(phenyl or heterocyclyl)-alkanol derivatives, are 5-HT(2A) receptor antagonists useful e.g. for treating schizophrenia, depression, memory disorders or eating disorders
US7345096B2 (en) 2002-10-15 2008-03-18 Wyeth Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
US7531543B2 (en) 2003-10-14 2009-05-12 Wyeth Phenylpiperazine cycloalkanol derivatives and methods of their use
US7402698B2 (en) 2003-10-14 2008-07-22 Wyeth Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
US7491723B2 (en) 2003-10-14 2009-02-17 Wyeth Alkanol and cycloalkanol-amine derivatives and methods of their use
US7524846B2 (en) 2003-10-14 2009-04-28 Wyeth Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use
US7365076B2 (en) 2003-10-14 2008-04-29 Wyeth Substituted aryl cycloalkanol derivatives and methods of their use
US7550485B2 (en) 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
US7419980B2 (en) 2003-10-14 2008-09-02 Wyeth Fused-aryl and heteroaryl derivatives and methods of their use
ES2515092T3 (en) 2003-12-11 2014-10-29 Sunovion Pharmaceuticals Inc. Combination of a sedative and a neurotransmitter modulator and methods of improving sleep quality and treating depression
DE102004010132A1 (en) 2004-02-27 2005-09-15 Merck Patent Gmbh piperidine
US7414052B2 (en) 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en) 2004-03-30 2009-04-14 Wyeth Phenylaminopropanol derivatives and methods of their use
US20060069124A1 (en) * 2004-09-07 2006-03-30 Rao P S Use of MDL-100,907 for treatment of allergic and eosinophil mediated diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3100775A (en) * 1959-04-01 1963-08-13 Searle & Co alpha-phenyl(pyridyl or piperidyl)alkyl esters of (chloro or lower alkoxy)-benzoic acids and congeners
ZA717147B (en) * 1970-11-27 1972-07-26 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives
SE7409245L (en) * 1973-07-19 1975-01-20 Robins Co Inc A H
FR2534580A1 (en) * 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
KR910006138B1 (en) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 Cyclic amine derivatives

Also Published As

Publication number Publication date
FI862801A0 (en) 1986-07-01
CA1280421C (en) 1991-02-19
CN1023895C (en) 1994-03-02
DK312386A (en) 1987-01-03
KR900001184B1 (en) 1990-02-27
NO862661L (en) 1987-01-05
HUT41387A (en) 1987-04-28
NO862661D0 (en) 1986-07-01
JPS625955A (en) 1987-01-12
ATE49403T1 (en) 1990-01-15
AU590582B2 (en) 1989-11-09
NO167384C (en) 1991-10-30
JPH0655720B2 (en) 1994-07-27
ZA864772B (en) 1987-02-25
IE861771L (en) 1987-01-02
CN86104408A (en) 1987-05-20
DK312386D0 (en) 1986-07-01
FI84474C (en) 1991-12-10
DE3668167D1 (en) 1990-02-15
PT82890B (en) 1988-05-27
GR861699B (en) 1986-10-31
EP0208235B1 (en) 1990-01-10
DK174153B1 (en) 2002-07-29
ES2000299A6 (en) 1988-02-16
HU196058B (en) 1988-09-28
EP0208235A1 (en) 1987-01-14
AR241904A1 (en) 1993-01-29
AU5931886A (en) 1987-01-08
IL79266A (en) 1990-04-29
NZ216689A (en) 1989-07-27
PH22141A (en) 1988-06-01
IE58460B1 (en) 1993-09-22
AR242184A1 (en) 1993-03-31
NO167384B (en) 1991-07-22
PT82890A (en) 1986-08-01
FI84474B (en) 1991-08-30
KR870001164A (en) 1987-03-11

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: MERRELL DOW PHARMACEUTICALS INC.

PC Transfer of assignment of patent

Owner name: AVENTIS INC.

Free format text: AVENTIS INC.

MA Patent expired