FI853574L - DIHYDROPYRIDINE -3,5-DICARBOXYLSYRAESTER DERIVATIVES. - Google Patents

DIHYDROPYRIDINE -3,5-DICARBOXYLSYRAESTER DERIVATIVES.

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Publication number
FI853574L
FI853574L FI853574A FI853574A FI853574L FI 853574 L FI853574 L FI 853574L FI 853574 A FI853574 A FI 853574A FI 853574 A FI853574 A FI 853574A FI 853574 L FI853574 L FI 853574L
Authority
FI
Finland
Prior art keywords
dihydropyridine
diastereoisomer
dicarboxylsyraester
derivatives
compounds
Prior art date
Application number
FI853574A
Other languages
Finnish (fi)
Other versions
FI83516B (en
FI853574A0 (en
FI83516C (en
Inventor
Kazuharu Tamazawa
Tadao Kojima
Hideki Arima
Yukiyasu Murakami
Yasuo Isomura
Minoru Okada
Kiyoshi Takanobu
Toichi Takenaka
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Priority to FI853574A priority Critical patent/FI83516C/en
Publication of FI853574A0 publication Critical patent/FI853574A0/en
Publication of FI853574L publication Critical patent/FI853574L/en
Publication of FI83516B publication Critical patent/FI83516B/en
Application granted granted Critical
Publication of FI83516C publication Critical patent/FI83516C/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention refers to new pharmaceutical compositions with both excellent vasodilatory activity on the coronary arteries and time of action. These are 2,6-dimethyl-4-(3- nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3- (benzylpyrrolidine-3-yl) ester 5-methylester's A- diastereoisomer, the hydrochloride of which has a melting point of 200 - 206 degree C (breaks up); the A-diastereoisomer's dextrorotatory isomer and pharmaceutically acceptable acid addition salts of these compounds. Pharmaceutical compounds according to the invention may be separated from mixtures containing other isomers with various methods, including chromatograph and fractional crystallization.
FI853574A 1985-09-18 1985-09-18 PHARMACEUTICAL FORM OF PHARMACOLOGICAL PROPERTIES 2,6-DIMETHYL-4- (3-NITROPHENYL) -1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLSYRA-3- (1-BENZYLPYRROLIDIN-3-YLMETH-3-YL) -ES-3-YL) -DIASTEREOISOMER. FI83516C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI853574A FI83516C (en) 1985-09-18 1985-09-18 PHARMACEUTICAL FORM OF PHARMACOLOGICAL PROPERTIES 2,6-DIMETHYL-4- (3-NITROPHENYL) -1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLSYRA-3- (1-BENZYLPYRROLIDIN-3-YLMETH-3-YL) -ES-3-YL) -DIASTEREOISOMER.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI853574A FI83516C (en) 1985-09-18 1985-09-18 PHARMACEUTICAL FORM OF PHARMACOLOGICAL PROPERTIES 2,6-DIMETHYL-4- (3-NITROPHENYL) -1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLSYRA-3- (1-BENZYLPYRROLIDIN-3-YLMETH-3-YL) -ES-3-YL) -DIASTEREOISOMER.
FI853574 1985-09-18

Publications (4)

Publication Number Publication Date
FI853574A0 FI853574A0 (en) 1985-09-18
FI853574L true FI853574L (en) 1987-03-19
FI83516B FI83516B (en) 1991-04-15
FI83516C FI83516C (en) 1991-07-25

Family

ID=8521370

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853574A FI83516C (en) 1985-09-18 1985-09-18 PHARMACEUTICAL FORM OF PHARMACOLOGICAL PROPERTIES 2,6-DIMETHYL-4- (3-NITROPHENYL) -1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLSYRA-3- (1-BENZYLPYRROLIDIN-3-YLMETH-3-YL) -ES-3-YL) -DIASTEREOISOMER.

Country Status (1)

Country Link
FI (1) FI83516C (en)

Also Published As

Publication number Publication date
FI83516B (en) 1991-04-15
FI853574A0 (en) 1985-09-18
FI83516C (en) 1991-07-25

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: YAMANOUCHI PHARMACEUTICAL CO., LTD

MA Patent expired