FI840261A - SUBSTITUTE PYRROLIDINONDERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING. - Google Patents

SUBSTITUTE PYRROLIDINONDERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING. Download PDF

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Publication number
FI840261A
FI840261A FI840261A FI840261A FI840261A FI 840261 A FI840261 A FI 840261A FI 840261 A FI840261 A FI 840261A FI 840261 A FI840261 A FI 840261A FI 840261 A FI840261 A FI 840261A
Authority
FI
Finland
Prior art keywords
pyrrolidinonderivat
substitute
foerfarande foer
och foerfarande
deras framstaellning
Prior art date
Application number
FI840261A
Other languages
Finnish (fi)
Other versions
FI840261A0 (en
Inventor
William Bencze
Bruno Kamber
Angelo Storni
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI840261A0 publication Critical patent/FI840261A0/en
Publication of FI840261A publication Critical patent/FI840261A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI840261A 1983-01-27 1984-01-23 SUBSTITUTE PYRROLIDINONDERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING. FI840261A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH45483 1983-01-27

Publications (2)

Publication Number Publication Date
FI840261A0 FI840261A0 (en) 1984-01-23
FI840261A true FI840261A (en) 1984-07-28

Family

ID=4187392

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840261A FI840261A (en) 1983-01-27 1984-01-23 SUBSTITUTE PYRROLIDINONDERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING.

Country Status (12)

Country Link
EP (1) EP0115473A3 (en)
JP (1) JPS59141544A (en)
KR (1) KR840007570A (en)
AU (1) AU2383984A (en)
DD (1) DD215539A5 (en)
DK (1) DK35984A (en)
FI (1) FI840261A (en)
GR (1) GR81747B (en)
IL (1) IL70791A0 (en)
NO (1) NO840311L (en)
PT (1) PT78008B (en)
ZA (1) ZA84595B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190378B (en) * 1985-06-21 1988-02-16 Isf Spa PYROLIDONIC DERIVATIVES
WO1989010359A1 (en) * 1988-04-22 1989-11-02 2 Moskovsky Gosudarstvenny Meditsinsky Institut Im Carbalkoxymethyl ethers of lactam-1-acetic acid and method of obtaining them
JP2997488B2 (en) * 1989-12-25 2000-01-11 興研株式会社 Tumor cell growth inhibitor
CA3231236A1 (en) * 2021-09-30 2023-04-06 Protinhi B.V. Protease inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT360980B (en) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works METHOD FOR PRODUCING N-ALKYLAMIDES OF 2-OXO-1-PYRROLIDINE
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
US4254107A (en) * 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin

Also Published As

Publication number Publication date
AU2383984A (en) 1984-08-02
GR81747B (en) 1984-12-12
EP0115473A2 (en) 1984-08-08
EP0115473A3 (en) 1987-01-21
DD215539A5 (en) 1984-11-14
ZA84595B (en) 1984-11-28
PT78008A (en) 1984-02-01
JPS59141544A (en) 1984-08-14
PT78008B (en) 1986-06-18
NO840311L (en) 1984-07-30
DK35984D0 (en) 1984-01-26
DK35984A (en) 1984-07-28
KR840007570A (en) 1984-12-08
IL70791A0 (en) 1984-04-30
FI840261A0 (en) 1984-01-23

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: CIBA-GEIGY AG